Skip to content

New strategies for Integrin Antagonism

The RGD binding integrins are involved in growth and metastasis of a number of cancers with significant unmet clinical need. Despite being the target of significant interest by the pharmaceutical industry, no effective integrin based anticancer agents have reached the clinic. We have developed a new integrin antagonist chemotype which can be applied to selective and polypharmacological antagonism or combination therapy involving integrin targeting.

IP position

UK Patent application was submitted in January 2023.

The opportunity

To progress selected compounds through lead optimisation.

For more information contact Dr. Jason Jones or the UoB Commercial Innovation Team

Integrin image