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Cardiovascular Research Group

Welcome to the Cardiovascular Research Group

The Cardiovascular Research Group brings together highly complementary expertise, enabling collaborative multi- and interdisciplinary research. Expertise within the group includes the fundamental biology of cardiovascular health and the molecular mechanisms involved in cardiovascular disease. Specific areas of research interests encompass endothelial and smooth muscle cell biology, cellular signalling, membrane biology and electrophysiology. The group performs cutting-edge research into a range of diseases and conditions associated with the malfunction of the cardiovascular system, including atherosclerosis, cardiac and vascular fibrosis, arrhythmias, type 2 and gestational diabetes, as well as pulmonary hypertension. To increase the impact of our research we work with vascular surgeons, structural biologists, computational scientists, as well as members of the public.

Blood cells travelling through blood vessels

Recent news

Northern Cardiovascular Research Group Meeting 2022
The 2022 meeting of the Northern Cardiovascular Research Group was held at Bradford University on 24th May. It was organised by Dr Matt Hardy with the help of Dr Jacobo Elies, Dr Kirsten Riches-Suman and Dr Munir Hussain and attracted 102 registered delegates from across the UK. The 2022 meeting brought together researchers and clinicians with a common interest in cardiovascular physiology and pathology and included a fantastic programme of talks and posters. The keynote speaker of the meeting was Dr. Samantha Pitt from the University of St. Andrews who discussed how “Cellular zinc shapes calcium dynamics in the heart".

Public Event: Pint of Science
Three academics from the Cardiovascular Research Group are taking part in the inaugural 'Pint of Science' Bradford event - the first time that this national initiative has set up a programme in our city. On Monday 9th May, Dr Jacobo Elies will be talking at the Bradford Sweet Centre about the possible beneficial use of toxic gasses such as hydrogen sulphide in cardiovascular health. On Wednesday 11th May, Professor Anne Graham and Dr Kirsten Riches-Suman will be talking at Theatre in the Mill all about the heart and blood vessels, and how age impacts them.

UNIfy Festival 2022
The Cardiovascular Research Group was represented with a stand at the CommUNIty Open Day of the UNIfy Festival 2022 on Saturday 26th March. The research team worked together with Clinical Sciences to interact with the public on the topics of "Hearts and Blood Vessels" and the "Clinical Sciences Health Check". Visitors could see real blood vessel cells in a microscope, explore models of hearts and blood vessels, check their blood pressure and body fat, or check out blood flow using a hand-held ultrasound device.

Northern Vascular Biology Forum (NVBF) meeting
The NVBF is a consortium of nine regional universities focussing on cardiovascular development and disease. The recent meeting on 14 December 2021 was hosted by the in the Faculty of Life Sciences. It featured 36 talks from across the region and was organized by Dr Kirsten Riches-Suman.

Please also follow us on Twitter: @CardiovascBfd.

Our PhD students

The Cardiovascular Research Group has a vibrant PhD student population. The group currently includes 16 PhD students working on a range of cardiovascular research projects.

Recent publications

Identifying and targeting the molecular signature of smooth muscle cells undergoing early vascular ageing.
Riches-Suman K, Hussain A.
Biochim Biophys Acta Mol Basis Dis. 2022 Jul 1;1868(7):166403.
doi: 10.1016/j.bbadis.2022.166403

Downregulation of Vascular Hemeoxygenase-1 Leads to Vasculopathy in Systemic Sclerosis.
Ross RL, Mavria G, Del Galdo F, Elies J
Front Physiol. 2022 May 5;13:900631
doi: 10.3389/fphys.2022.900631

Efficacy of interval exercise training to improve vascular health in sedentary postmenopausal females.
Lyall GK, Birk GK, Harris E, Ferguson C, Riches-Suman K, Kearney MT, Porter KE, Birch KM.
Physiol Rep. 2022 Aug;10(16):e15441
doi: 10.14814/phy2.15441

Impact of Pharmacist-Led Interventions to Improve Clinical Outcomes for Adults With Type 2 Diabetes at Risk of Developing Cardiovascular Disease: A Systematic Review and Meta-analysis.
Alabkal RM, Medlinskiene K, Silcock J, Graham A.
J Pharm Pract. 2022 May 17:8971900211064459
doi: 10.1177/08971900211064459

Preservation of Smooth Muscle Cell Integrity and Function: A Target for Limiting Abdominal Aortic Aneurysm Expansion?
Clark ER, Helliwell RJ, Bailey MA, Hemmings KE, Bridge KI, Griffin KJ, Scott DJA, Jennings LM, Riches-Suman K, Porter KE.
Cells. 2022 Mar 19;11(6):1043
doi: 10.3390/cells11061043

Please follow this link for additional publications: Full list of our recent publications

Group members

The group currently consists of the following researchers that perform collaborative, multi-disciplinary work to advance cardiovascular research at the University of Bradford. To inquire about our research, please email the group lead, Jürgen Müller.