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Dr Venu Vangala

Assistant Professor

Faculty/Dept/School School of Pharmacy and Medical Sciences
(Faculty of Life Sciences)
Telephone +441274 236116


Venu Vangala joined as Lecturer in Medicines Development and Pharmaceutical Sciences. His research work focuses on building strong capability in interdisciplinary areas of fundamental and applied solid-state pharmaceuticals and pharmaceutical technology. Currently, he is involved in industrial collaborative projects with Advanced Extrusion Technology and N4 Pharma Ltd., UK.


Crystal engineering for the development of functional pharmaceutical materials Solid state pharmaceuticals – cocrystals, polymorphs, salts and amorphous materials Physicochemical characterization of pharmaceutical solids Develop understanding of crystal structure vs pharmaceutical properties

Current Projects Screening and characterization of novel co-crystals involving active pharmaceutical ingredients.

Research Collaborations University of Minnesota, IISER Kolkata, University of Lucknow, University of Iowa.


TitleInterfacial Cocrystallization Using Oily Phase via Liquid−Liquid Phase Separation (2022)
AuthorsM. Asim Sajid Al-Hanafi, Mhd Bashir Alsirawan, Colin C. Seaton, Thomas Swift, Sudhir Pagire, Venu R. Vangala, Adrian L. Kelly, and Anant Paradkar
TitleCytochrome P450 Binding and Bioactivation of Tumor-targeted Duocarmycin Agents. (2021)
AuthorsBart AG;Morais G;Vangala VR;Loadman PM;Pors K;Scott EE;
JournalDrug Metabolism And Disposition: The Biological Fate Of Chemicals
TitleIsomorphism: 'Molecular similarity to crystal structure similarity' in multicomponent forms of analgesic drugs tolfenamic and mefenamic acid (2020)
AuthorsRanjan S.;Devarapalli R.;Kundu S.;Saha S.;Deolka S.;Vangala V.R.;Reddy C.M.
TitleStructural Basis for Mechanical Anisotropy in Polymorphs of Caffeine-Glutaric Acid Cocrystal (2020)
AuthorsManish Kumar Mishra,* Kamini Mishra, Aditya Narayan, C. Malla Reddy* and Venu R. Vangala*
PublisherAmerican Chemical Society
TitleIntriguing High Z″ Cocrystals of Emtricitabine (2020)
AuthorsPalanisamy V.;Sanphui P.;Bolla G.;Narayan A.;Seaton C.C.;Vangala V.R.
JournalCrystal Growth and Design
TitleSolid-State Competitive Destabilization of Caffeine Malonic Acid cocrystal: Mechanistic and Kinetic Investigation (2020)
AuthorsM. Bashir Alsirawan, Xiaojun Lai, Rafel Prohens, Venu Vangala, Sudhir Pagire, Petro Shelley, Thomas Bannan, David Topping, and Anant Paradkar
JournalCrystal Growth and Design
PublisherAmerican Chemical Society
DOIDOI: 10.1021/acs.cgd.0c01246
TitleMechanistic Understanding of Competitive Destabilization of Carbamazepine Cocrystals under Solvent Free Conditions (2020)
AuthorsMHD Bashir Alsirawan, Xiaojun Lai, Rafel Prohens, Venu R. Vangala, Petroc Shelley, Thomas J. Bannan, David O. Topping, and Anant Paradkar
TitleIntriguing High Z'' Cocrystals of Emtricitabine (2020)
AuthorsVasanthi Palanisamy, Palash Sanphui, Geetha Bolla, Aditya Narayan, Colin C. Seatond and Venu R. Vangala
PublisherCrystal Growth & Design
TitleStructural and reactivity analyses of nitrofurantoin 4 dimethylaminopyridine salt using spectroscopic and density functional theory calculations (2019)
AuthorsKhan E; Shukla A; Srivastava K; Gangopadhyay D; Assi K; Tandon P; Vangala V
TitleNitrofurantoin-melamine monohydrate (cocrystal hydrate): Probing the role of H-bonding on the structure and properties using quantum chemical calculations and vibrational spectroscopy (2019)
AuthorsKhan E.;Shukla A.;Jhariya A.;Tandon P.;Vangala V.
JournalSpectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
TitleStudy of molecular interactions and chemical reactivity of the nitrofurantoin-3-aminobenzoic acid cocrystal using quantum chemical and spectroscopic (IR, Raman,13C SS-NMR) approaches (2017)
AuthorsShukla A.;Khan E.;Srivastava K.;Sinha K.;Tandon P.;Vangala V.
TitleThree new hydrochlorothiazide cocrystals: Structural analyses and solubility studies (2017)
AuthorsRanjan, S.; Devarapalli, R.; Kundu, S.; Vangala, Venu R.; Ghosh, A.; Reddy, C.A.
TitleThermodynamic investigation of carbamazepine-saccharin co-crystal polymorphs (2017)
AuthorsPagire, Sudhir K.; Jadav, Niten B.; Vangala, Venu R.; Whiteside, Benjamin R.; Paradkar, Anant R.
TitleStudy of molecular structure, chemical reactivity and H-bonding interactions in the cocrystal of nitrofurantoin with urea (2017)
AuthorsKhan, E.; Shukla, A.; Jadav, Niten B.; Telford, Richard; Ayala, A.P.; Tandon, P.; Vangala, Venu R.
TitleThermal and in situ x-ray diffraction analysis of a dimorphic co-crystal 1:1 caffeine-glutaric acid (2015)
AuthorsVangala, Venu R.; Chow, P.S.; Schreyer, M.; Lau, G.; Tan, R.B.H.

Other typeReviews
TitlePharmaceutical Cocrystals: Molecules, Crystals, Formulations, Medicines (2019)
AuthorsYousef M.;Vangala V.
JournalCrystal Growth and Design