Recovery of low volumes of wear debris from rat stifle joint tissues using a novel particle isolation method
Patel, J.; Lal, S.; Nuss, K.; Wilshaw, Stacy-Paul; von Rechenberg, B.; Hall, R.M.; Tipper, J.L. (2018)
Dr. Stacy-Paul Wilshaw
Research
Acellular biological scaffolds for tissue repair and regeneration.
A range of acellular biological scaffolds have been developed which may have clinical application for repair and regeneration, as in vitro models of disease or applied to in vitro drug screening. These biological scaffolds are devoid of cells and cell remnants and have demonstrated a capacity for regeneration however the role of the body’s immune system in the regenerative process is largely unknown. Current research focuses on the application of acellular scaffolds for cardiovascular repair and peripheral nerve replacement, alongside the development of liver grafts and the application of human amniotic membrane to restore damaged cornea and as a cell carrier. Elucidating the mechanisms though which acellular scaffolds regenerate in vivo and the role of the immune system in this process.
Publications
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Development and characterisation of a large diameter decellularised vascular allograft
Aldridge, A.; Desai, A.; Owston, H.; Jennings, L.M.; Fisher, J.; Rooney, P.; Kearney, J.N.; Ingham, E.; Wilshaw, Stacy-Paul (2018)
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Validation of a novel particle isolation procedure using particle doped tissue samples
Patel, J.; Lal, S.; Wilshaw, Stacy-Paul; Hall, R.M.; Tipper, J.L. (2018)
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Gamma-irradiated human amniotic membrane decellularised with sodium dodecyl sulfate is a more efficient substrate for the ex vivo expansion of limbal stem cells
Figueiredo, G.S.; Bojic, S.; Rooney, P.; Wilshaw, Stacy-Paul; Connon, C.J.; Gouveia, R.M.; Paterson, C.; Lepert, G.; Mudhar, H.S.; Figueiredo, F.C.; Lako, M. (2017)
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Decellularisation and histological characterisation of porcine peripheral nerves
Zilic, L.; Wilshaw, Stacy-Paul; Haycock, J.W. (2016)
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An anatomical study of porcine peripheral nerve and its potential use in nerve tissue engineering
Zilic, L.; Garner, P.E.; Yu, Tong; Roman, S.; Haycock, J.W.; Wilshaw, Stacy-Paul (2015)
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Development and Characterization of Acellular Porcine Pulmonary Valve Scaffolds for Tissue Engineering
Luo, J.; Korossis, S.A.; Wilshaw, Stacy-Paul; Jennings, L.M.; Fisher, J.; Ingham, E. (2014)
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Assessment of the antimicrobial activity of acellular vascular grafts
Owen K.;Wilshaw S.;Homer-Vanniasinkam S.;Bojar R.;Berry H.;Ingham E. (2012) European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery. 43, 573-581.
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The use of antithrombotic therapies in reducing synthetic small-diameter vascular graft thrombosis.
Tatterton M;Wilshaw SP;Ingham E;Homer-Vanniasinkam S; (2012) Vascular and Endovascular Surgery. 46
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Development and characterization of acellular allogeneic arterial matrices.
Wilshaw SP;Rooney P;Berry H;Kearney JN;Homer-Vanniasinkam S;Fisher J;Ingham E; (2012) Tissue Engineering - Part A.. 18
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Investigation of the antiadhesive properties of human mesothelial cells cultured in vitro on implantable surgical materials
Wilshaw S.;Burke D.;Fisher J.;Ingham E. (2009) Journal of Biomedical Materials Research - Part B Applied Biomaterials. 88, 49-60.
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Factors influencing the oxygen consumption rate of aortic valve interstitial cells: application to tissue engineering.
Wang L;Wilshaw SP;Korossis S;Fisher J;Jin Z;Ingham E; (2009) Tissue Engineering - Part C: Methods. 15
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The effect of amniotic membrane preparation method on its ability to serve as a substrate for the ex-vivo expansion of limbal epithelial cells.
Shortt AJ;Secker GA;Lomas RJ;Wilshaw SP;Kearney JN;Tuft SJ;Daniels JT; (2009) Biomaterials. 30
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Cytocompatibility of poly(1,2 propandiol methacrylate) copolymer hydrogels and conetworks with or without alkyl amine functionality
Rimmer S.;Wilshaw S.;Pickavance P.;Ingham E. (2009) Biomaterials. 30, 2468-2478.