Pharmacokinetics and tumour drug metabolism of anti-cancer drugs
Professor Paul Loadman heads the drug
metabolism team at the Institute of Cancer Therapeutics, University of Bradford
and has >20years experience studying
the pharmacokinetics and metabolism of anti-cancer drugs. The team in Bradford have
studied a wide range of clinically available and novel small molecules
including antimetabolites, platinating and alkylating agents, peptides and
antivascular compounds. Prof Loadman is actively involved in the design,
analysis and reporting of pre-clinical and clinical pharmacokinetic studies and
acts as a pharmacokinetic and drug metabolism consultant for numerous
pharmaceutical and biotechnology companies.
Together
with Prof Twelves (Clinical
Director,) the DMPK team have established a Quality Management System within
the ICT which has enabled a strong involvement in the pharmacokinetic
monitoring of small molecules in major clinical trials. Other major clinical collaborations
include with Professor Mark Hull at the University of Leeds (The seAFOod Polyp Prevention Trial, www.seafood-trial.co.uk) where the laboratory in Bradford are analyzing a series of bioactive lipid
mediators such as ω-3 PUFAs, resolvin E1 and PGE-M in plasma, urine,
erythrocytes and rectal mucosa in order to gain insights into the mechanism of
action of EPA and aspirin.
Ge SunJohn, R Davies ,Tracey Mell, Mark Harland, Rasha M H Saleh, Amanda D Race, Paul M Loadman, Elizabeth A Williams, Anne Marie Minihane, Mark A Hull (2024) Prostaglandins Leukotrienes and Essential Fatty Acids. 201
Adam Throup;Manar Saleh Zraikat;Andrew Gordon;Shohreh Jafarinejad Soumehsaraei;Kathrin D Haase;Laurence H Patterson;Patricia A Cooper;Katherine Hanlon;Paul M Loadman;Mark Sutherland;Steven D Shnyder;Helen M Sheldrake (2024) Rsc Medicinal Chemistry.
Barnieh FM;Galuska SP;Loadman PM;Ward S;Falconer RA;El-Khamisy SF; (2023) Iscience. 26
Ge Sun, Harriett Fuller, Hayley Fenton, Amanda D. Race, Amy Downing, Elizabeth A. Williams, Colin J. Rees, Louise C. Brown, Paul M. Loadman, Mark A. Hull (2023) International Journal of Cancer. 00
Downing A;Fenton H;Nickerson C;Loadman PM;Williams EA;Rees CJ;Brown LC;Morris EJA;Hull MA; (2023) Alimentary Pharmacology and Therapeutics.
John R Davies, Tracey Mell, Harriett Fuller, Mark Harland, Rasha N M Saleh, Amanda D Race, Colin J Rees, Louise C Brown, Paul M Loadman, Amy Downing, Anne Marie Minihane, Elizabeth A Williams Mark A Hull (2023) Cancer Prevention Research. september
Fuller H;Race AD;Fenton H;Burke L;Downing A;Williams EA;Rees CJ;Brown LC;Loadman PM;Hull MA; (2023) Prostaglandins Leukotrienes and Essential Fatty Acids. 192
Mark A Hull , Pei Loo Ow, Sharon Ruddock, Tim Brend, Alexandra F Smith, Helen Marshall, Mingyang Song, Andrew T Chan, Wendy S Garrett, Omer Yilmaz, David A Drew, Fiona Collinson, Andrew J Cockbain, Robert Jones, Paul M Loadman , Peter S Hall, Catherine Moriarty, David A Cairns, Giles J Toogood (2023) BMJ Open. 13
Ingram N;McVeigh LE;Abou-Saleh RH;Batchelor DVB;Loadman PM;McLaughlan JR;Markham AF;Evans SD;Coletta PL; (2022) Pharmaceutics. 14
Eschweiler S;Ramírez-Suástegui C;Li Y;King E;Chudley L;Thomas J;Wood O;von Witzleben A;Jeffrey D;McCann K;Simon H;Mondal M;Wang A;Dicker M;Lopez-Guadamillas E;Chou TF;Dobbs NA;Essame L;Acton G;Kelly F;Halbert G;Sacco JJ;Schache AG;Shaw R;McCaul JA;Paterson C;Davies JH;Brennan PA;Singh RP;Loadman PM;Wilson W;Hackshaw A;Seumois G;Okkenhaug K;Thomas GJ;Jones TM;Ay F;Friberg G;Kronenberg M;Vanhaesebroeck B;Vijayanand P;Ottensmeier CH; (2022) Nature. 605
Ian S. Miller, Sonja Khan, Liam P. Shiels, Sudipto Das, Alice C. O' Farrell, Kate Connor, Adam Lafferty, Bruce Moran, Claudio Isella, Paul Loadman, Emer Conroy, Susan Cohrs, Roger Schibli, Robert S. Kerbel, William M. Gallagher, Elisabetta Marangoni, Kathleen Bennett, Darran P. O' Connor, Róisín M. Dwyer, Annette T. Byrne (2022) Cancer Medicine. 11
Spencer, H.L.M.; Shnyder, S.D.; Loadman, P.M.; Falconer, R.A. (2022) Journal of Cancer Metastasis and Treatment. 9
(2022) Biochemical Pharmacology.
Jukes Z;Morais GR;Loadman PM;Pors K; (2021) Drug Discovery Today. 26
Presa D;Khurram SA;Zubir AZA;Smarakan S;Cooper PA;Morais GR;Sadiq M;Sutherland M;Loadman PM;McCaul J;Shnyder SD;Patterson LH;Pors K; (2021) Scientific Reports. 11
Natalia Ortuzar, Kersti Karu, Daniela Presa, Goreti R. Morais, Helen M. Sheldrake, Steve D. Shnyder, Francis M. Barnieh, Paul M. Loadman, Laurence H. Patterson, Klaus Pors, Mark Searcey (2021) BIOORGANIC & MEDICINAL CHEMISTRY. 40
Gael Nana, Henry Watson, Suparna Mitra, Caroline Young, Henry M Wood, Sarah L Perry, Amanda D Race, Philip Quirke, Giles J Toogood, Paul M Loadman, Mark A Hull (2021) Journal of Nutrition. may24
Ortuzar N;Karu K;Presa D;Morais GR;Sheldrake HM;Shnyder SD;Barnieh FM;Loadman PM;Patterson LH;Pors K;Searcey M; (2021) Bioorganic and Medicinal Chemistry. 40
Charalambous A;Mico V;McVeigh LE;Marston G;Ingram N;Volpato M;Peyman SA;McLaughlan JR;Wierzbicki A;Loadman P;Bushby RJ;Markham AF;Evans SD;Coletta PL; (2021) Nanomedicine: Nanotechnology, Biology, and Medicine.
Guo, X.; Elkashef, S.M.; Patel, A.; Ribeiro Morais, G.; Shnyder S.D.; Loadman, P.M.; Patterson, L.H.; Falconer, R.A. (2021) Carbohydrate Polymers. 259
Barnieh, F.M.; Loadman, P.M.; Falconer, R.A. (2021) Current Research in Pharmacology and Drug Discovery. 2
Barnieh FM;Loadman PM;Falconer RA; (2021) Biochimica et Biophysica Acta - Reviews on Cancer. 1876
Bart AG;Morais G;Vangala VR;Loadman PM;Pors K;Scott EE; (2021) Drug Metabolism And Disposition: The Biological Fate Of Chemicals.
Nicola Ingram1*, Laura E. McVeigh1*, Radwa H. Abou-Saleh2,3, Juliana Maynard4, Sally A. Peyman2, James R. McLaughlan5, Michael Fairclough6, Gemma Marston1, Elizabeth M.A. Valleley 1, Jorge L. Jimenez-Macias1, Antonia Charalambous1, William Townley4, Malcolm Haddrick4, Antonia Wierzbicki7, Alexander Wright1, Milène Volpato1, Peter B. Simpson4, Darren E. Treanor1, Neil H. Thomson8, Paul M. Loadman7, Richard J. Bushby2,9, Benjamin R.G. Johnson2, Pamela F. Jones1, Tony Evans1, Steven Freear5, Alexander F. Markham1, Stephen D. Evans2,*, P. Louise Coletta1,* (2020) Theranostics. 10
Guo X; Malcolm J.R.; Ali M.M.; Ribeiro Morais G; Shnyder S.D.; Loadman P.M.; Patterson L.H.; Falconer R.A. (2020) ANALYST (PRINT). 145, 4512-4521.
Roger M. Phillips, Paul M. Loadman, Guru Reddy (2019) Cancer Chemotherapy and Pharmacology. 83
Wu, W.; Klockow, J.L.; Mohanty, S.; Ku, K.S.; Aghighi, M.; Melemenidis, S.; Chen, Z.; Li, K.; Ribeiro Morais, Goreti; Zhao, N.; Schlegel, J.; Graves, E.E.; Rao, J.; Loadman, Paul M.; Falconer, R.A.; Mukherjee, S.; Chin, F.T.; Daldrup-Link, H.E. (2019) Nanotheranostics. 3, 299-310.
Jove, M.; Spencer, Jade A.; Clench, M.; Loadman, Paul M.; Twelves, C. (2019) Critical Reviews in Oncology/Hematology. 141, 153-162.
Xiaoxiao Guo, Sara M. Elkashef, Mark Sutherland, Paul M. Loadman and Robert A. Falconer (2019) Carbohydrate Polymers. 16
Jove M;Spencer JA;Hubbard ME;Holden EC;O'Dea RD;Brook BS;Phillips RM;Smye SW;Loadman P;Twelves CJ; (2019) Journal of Pharmacology and Experimental Therapeutics. 371
Hull, M.A.; Sprange, K.; Hepburn, T.; Tan, W.; Shafayat, A.; Rees, C.J.; Clifford, G.; Logan, R.F.; Loadman, Paul M.; Williams, E.A.; Whitham, D.; Montgomery, A.A. (2018) Lancet. 392, 2583-2594.
Spriggs, S.; Cubberley, R.; Loadman, Paul M.; Sheffield, D.; Wierzbicki, Antonia (2018) Toxicology Letters. 292, 63-72.
Watson, H.; Mitra, S.; Croden, F.C.; Taylor, M.; Wood, H.M.; Perry, S.L.; Spencer, Jade A.; Quirke, P.; Toogood, G.J.; Lawton, C.L.; Dye, L.; Loadman, Paul M.; Hull, M.A. (2018) Gut. 67, 1974-1983.
Kamble, Sharad R.; Loadman, Paul M.; Abraham, M.H.; Liu, Xiangli (2018) Journal of Pharmaceutical and Biomedical Analysis. 149, 16-21.
Mohanty, S.; Chen, Z.; Li, K.; Ribeiro Morais, G.; Klockow, J.; Yerneni, K.; Pasani, L.; Chin, F.T.; Mitra, S.; Cheshier, S.; Chang, E.; Gambhir, S.S.; Rao, J.; Loadman, P.M.; Falconer, R.A.; Daldrup-Link, H.E. (2017) Molecular Cancer Therapeutics. 16, 1909-1921.
Hubbard, M.E.; Jove, M.; Loadman, Paul M.; Phillips, Roger M.; Twelves, Christopher J.; Smye, S.W. (2017) Royal Society Open Science. 4
Falconer, R.A.; Loadman, P.M. (2017) Journal of Cancer Metastasis and Treatment. 3, 315-327.
Jain, M.; Harburn, J.J.; Gill, J.H.; Loadman, P.M.; Falconer, R.A.; Mooney, C.A.; Cobb, S.L.; Berry, David J. (2017) Journal of Medicinal Chemistry. 60, 4496-4502.
Volpato, Milène; Spencer, Jade A.; Race, Amanda D.; Munarini, A.; Belluzzi, A.; Cockbain, A.; Hull, M.; Loadman, Paul M. (2017) J Chromatography B. 1055, 125-134.
Elkashef, Sara M.; Allison, Simon J.; Sadiq, Maria; Basheer, Haneen A.; Ribeiro Morais, Goreti; Loadman, Paul M.; Pors, Klaus; Falconer, Robert A. (2016) Scientific Reports. 6
Elkashef, Sara M.; Sutherland, Mark H.; Patterson, Laurence H.; Loadman, Paul M.; Falconer, Robert A. (2016) ANALYST (PRINT). 141, 5849-5856.
Watson, H.; Cockbain, A.J.; Spencer, Jade A.; Race, Amanda D.; Volpato, Milène; Loadman, Paul M.; Toogood, G.J.; Hull, M.A. (2016) Prostaglandins Leukotrienes and Essential Fatty Acids. 115
Vandooren, J.; Opdenakker, G.; Loadman, Paul M.; Edwards, D.R. (2016) Advanced Drug Delivery Reviews. 97, 144-145.
Vinader, Victoria; Sadiq, Maria; Sutherland, Mark H.; Huang, M.Y.; Loadman, Paul M.; Elsalem, Lina M.I.; Shnyder, Steven D.; Cui, H.J.; Afarinkia, Kamyar; Searcey, M.; Patterson, Laurence H.; Pors, Klaus (2015) MedChemComm. 6, 187-191.
Batubara, A.; Carolan, V.A.; Loadman, Paul M.; Sutton, Chris W.; Shnyder, Steven D.; Clench, M.R. (2015) Rapid Communications In Mass Spectrometry. 29, 1288-1296.
Wong, C.C.; Periasamy, Nagarajan; Sagineedu, S.R.; Sidik, S.; Sumon, S.H.; Loadman, Paul M.; Phillips, Roger M.; Lajis, N.H.; Stanslas, J. (2014) Investigational New Drugs. 32, 806-814.
Piazzi, G.; D'Argenio, G.; Prossomariti, A.; Lembo, V.; Mazzone, G.; Candela, M.; Biagi, E.; Brigidi, P.; Vitaglione, P.; Fogliano, V.; D'Angelo, L.; Fazio, C.; Munarini, A.; Belluzzi, A.; Ceccarelli, C.; Chieco, P.; Balbi, T.; Loadman, Paul M.; Hull, M.A.; Romano, M.; Bazzoli, F.; Ricciardiello, L. (2014) International Journal of Cancer. 135, 204-213.
Gill, Jason H.; Loadman, Paul M.; Shnyder, Steven D.; Cooper, Patricia A.; Atkinson, Jennifer M.; Ribeiro Morais, Goreti; Patterson, Laurence H.; Falconer, Robert A. (2014) Molecular Cancer Therapeutics. 11, 1294-1300.
Ansari, C.; Tikhomirov, G.A.; Hong, S.H.; Falconer, Robert A.; Loadman, Paul M.; Gill, Jason H.; Castaneda, R.; Hazard, F.K.; Tong, L.; Lenkov, O.D.; Felsher, D.W.; Rao, J.; Daldrup-Link, H.E. (2014) Small. 10, 565-575.
Cockbain, A.J.; Volpato, Milène; Race, Amanda D.; Munarini, A.; Fazio, C.; Belluzzi, A.; Loadman, Paul M.; Toogood, G.J.; Hull, M.A. (2014) Gut. 63, 1760-1768.
Kant, P.; Perry, S.L.; Dexter, S.P.; Race, Amanda D.; Loadman, Paul M. (2014) Bmc Obesity. 22, 202-210.
Groh, C.M.; Hubbard, M.E.; Jones, P.F.; Loadman, Paul M.; Periasamy, Nagarajan; Sleeman, B.D.; Smye, S.W.; Twelves, Christopher J.; Phillips, Roger M. (2014) Journal of the Royal Society Interface. 11
Sutherland, Mark H.; Gill, Jason H.; Loadman, Paul M.; Laye, Jonathan P.; Sheldrake, Helen M.; Illingworth, Nicola A.; Alandas, Mohammed N.; Cooper, Patricia A.; Searcey, M.; Pors, Klaus; Shnyder, Steven D.; Patterson, Laurence H. (2013)
Al-Saraireh, Yousef M.J.; Sutherland, Mark H.; Springett, Bradley R.; Freiberger, F.; Ribeiro Morais, Goreti; Loadman, Paul M.; Errington, R.J.; Smith, P.J.; Fukuda, M.; Gerardy-Schahn, R.; Patterson, Laurence H.; Shnyder, Steven D.; Falconer, Robert A. (2013) PLoS ONE. 8
Shaheed, Sadr-ul; Rustogi, Nitin; Scally, Andy J.; Wilson, J.; Thygesen, H.; Loizidou, M.A.; Hadjisavvas, A.; Hanby, A.; Speirs, V.; Loadman, Paul M.; Linforth, R.; Kyriacou, K.; Sutton, Chris W. (2013)
Hull M.;Sandell A.;Montgomery A.;Logan R.;Clifford G.;Rees C.;Loadman P.;Whitham D. (2013) Trials. 14
Hull, M.A.; Sandell, A.C.; Montgomery, A.A.; Logan, R.F.A.; Clifford, G.M.; Rees, C.J.; Loadman, Paul M.; Whitham, D. (2013)
Travica, S.; Pors, Klaus; Loadman, Paul M.; Shnyder, Steven D.; Johansson, I.; Alandas, Mohammed N.; Sheldrake, Helen M.; Mkrtchian, S.; Patterson, Laurence H.; Ingelman-Sundberg, M. (2013)
Djidja, M-C.; Francese, S.; Claude, E.; Loadman, Paul M.; Sutton, Chris W.; Shnyder, Steven D.; Cooper, Patricia A.; Patterson, Laurence H.; Carolan, V.A.; Clench, M.R. (2013)
Sheldrake, Helen M.; Travica, S.; Johansson, I.; Loadman, Paul M.; Sutherland, Mark H.; Elsalem, Lina M.I.; Illingworth, Nicola A.; Cresswell, Alexander J.; Reuillon, Tristan; Shnyder, Steven D.; Mkrtchian, S.; Searcey, M.; Ingelman-Sundberg, M.; Patterson, Laurence H.; Pors, Klaus (2013)
Cosentino L.;Redondo-Horcajo M.;Zhao Y.;Santos A.;Chowdury K.;Vinader V.;Abdallah Q.;Abdel-Rahman H.;Fournier-Dit-Chabert J.;Shnyder S.;Loadman P.;Fang W.;Díaz J.;Barasoain I.;Burns P.;Pors K. (2012) Journal of Medicinal Chemistry. 55, 11062-11066.
Fournier-Dit-Chabert J.;Vinader V.;Santos A.;Redondo-Horcajo M.;Dreneau A.;Basak R.;Cosentino L.;Marston G.;Abdel-Rahman H.;Loadman P.;Shnyder S.;Díaz J.;Barasoain I.;Falconer R.;Pors K. (2012) Bioorganic and Medicinal Chemistry Letters. 22, 7693-7696.
Hawcroft G.;Volpato M.;Marston G.;Ingram N.;Perry S.;Cockbain A.;Race A.;Munarini A.;Belluzzi A.;Loadman P.;Coletta P.;Hull M. (2012) British Journal of Pharmacology. 166, 1724-1737.
Tomlinson D.;Baxter E.;Loadman P.;Hull M.;Knowles M. (2012) PLoS ONE. 7
Pors, Klaus; Loadman, Paul M.; Shnyder, Steven D.; Sutherland, Mark H.; Sheldrake, Helen M.; Guino, M.; Kiakos, K.; Hartley, J.A.; Searcey, M.; Patterson, Laurence H. (2011)
Shnyder S.;Fu Y.;Habtemariam A.;Van Rijt S.;Cooper P.;Loadman P.;Sadler P. (2011) MedChemComm. 2, 666-668.
Al-Hasawi N.;Volapato M.;Loadman P. (2011) Kuwait Journal of Science and Engineering. 38, 107-130.
Benelkebir H.;Marie S.;Hayden A.;Lyle J.;Loadman P.;Crabb S.;Packham G.;Ganesan A. (2011) Bioorganic and Medicinal Chemistry. 19, 3650-3658.
Atkinson, Jennifer M.; Falconer, Robert A.; Edwards, D.R.; Pennington, C.J.; Siller, Catherine S.; Shnyder, Steven D.; Bibby, Michael C.; Patterson, Laurence H.; Loadman, Paul M.; Gill, Jason H. (2010)
Hawcroft, G.; Loadman, Paul M.; Belluzzi, A.; Hull, M.A. (2010)
Atkinson J.;Falconer R.;Edwards D.;Pennington C.;Siller C.;Shnyder S.;Bibby M.;Patterson L.;Loadman P.;Gill J. (2010) Cancer Research. 70, 6902-6912.
Hawcroft G.;Loadman P.;Belluzzi A.;Hull M. (2010) Neoplasia. 12, 618-627.
Isambert, N.; Campone, M.; Bourbouloux, E.; Drouin, M.; Major, A.; Yin, W.; Loadman, Paul M.; Capizzi, R.; Grieshaber, C.; Fumoleau, P. (2010)
Hochhauser, D.; Meyer, T.; Spanswick, V.J.; Wu, J.; Clingen, P.H.; Loadman, Paul M.; Cobb, M.; Gumbrell, L.; Begent, R.H.; Hartley, J.A.; Jodrell, D. (2009)
Williams K.;Albertella M.;Fitzpatrick B.;Loadman P.;Shnyder S.;Chinje E.;Telfer B.;Dunk C.;Harris P.;Stratford I. (2009) Molecular Cancer Therapeutics. 8, 3266-3275.
Steward, W.P.; Middleton, M.; Benghiat, A.; Loadman, Paul M.; Hayward, C.; Walter, S.; Ford, S.; Halbert, G.; Patterson, Laurence H.; Talbot, D. (2009)
Djidja, M-C.; Francese, S.; Loadman, Paul M.; Sutton, Chris W.; Scriven, P.; Claude, E.; Snel, M.F.; Franck, J.; Salzet, M.; Clench, M.R. (2009)
Djidja M.;Francese S.;Loadman P.;Sutton C.;Scriven P.;Claude E.;Snel M.;Franck J.;Salzet M.;Clench M. (2009) Proteomics. 9, 2750-2763.
Evans, C.J.; Phillips, Roger M.; Jones, P.F.; Loadman, Paul M.; Sleeman, B.D.; Twelves, Christopher J.; Smye, S.W. (2009)
Williams, K.J.; Albertella, M.R.; Fitzpatrick, B.; Loadman, Paul M.; Shnyder, Steven D.; Chinje, E.C.; Telfer, B.A.; Dunk, C.R.; Harris, P.A.; Stratford, I.J. (2009)
Djidja, M-C.; Carolan, V.A.; Loadman, Paul M.; Clench, M.R. (2008)
Albertella M.;Loadman P.;Jones P.;Phillips R.;Rampling R.;Burnet N.;Alcock C.;Anthoney A.;Vjaters E.;Dunk C.;Harris P.;Wong A.;Lalani A.;Twelves C. (2008) Clinical Cancer Research. 14, 1096-1104.
Albertella, M.R.; Loadman, Paul M.; Jones, P.H.; Phillips, Roger M.; Rampling, R.; Burnet, N.; Alcock, C.; Anthoney, Alan; Vjaters, E.; Dunk, C.R.; Harris, P.A.; Wong, A.; Lalani, A.S.; Twelves, Christopher J. (2008)
Wells, G.; Suggitt, Marie; Coffils, M.; Baig, M.A.H.; Howard, P.W.; Loadman, Paul M.; Hartley, J.A.; Jenkins, Terence C.; Thurston, D.E. (2008)
Burger, A.M.; Loadman, Paul M.; Thurston, D.E.; Schultz, R.; Fiebig, H.H.; Bibby, Michael C. (2007)
Volpato, Milène; Abou-Zeid, N.; Tanner, R.W.; Glassbrook, L.T.; Taylor, James P.; Stratford, I.J.; Loadman, Paul M.; Jaffar, M.; Phillips, Roger M. (2007)
Steward W.;Middleton M.;Benghiat A.;Loadman P.;Hayward C.;Waller S.;Ford S.;Halbert G.;Patterson L.;Talbot D. (2007) Annals of Oncology. 18, 1098-1103.
Atkinson J.;Pennington C.;Martin S.;Anikin V.;Mearns A.;Loadman P.;Edwards D.;Gill J. (2007) European Journal of Cancer. Part A. 43, 1764-1771.
Atkinson S.;Loadman P.;Sutton C.;Patterson L.;Clench M. (2007) Rapid Communications In Mass Spectrometry. 21, 1271-1276.
Atkinson, Jennifer M.; Gill, Jason H.; Loadman, Paul M.; Martin, Sandie W.; Pennington, J.; Anikin, V.A.; Mearns, A.J.; Edwards, D.R. (2007)
Puri, Rajiv; Palit, V.; Loadman, Paul M.; Flannigan, G. Michael; Shah, T.K.; Choudry, G.A.; Basu, Saurajyoti; Double, John A.; Lenaz, G.; Chawla, S.; Beer, M.; Kalken, C.V.; de Boer, R.; Beijnen, J.H.; Twelves, Christopher J.; Phillips, Roger M. (2006)
Wells G.;Martin C.;Howard P.;Sands Z.;Laughton C.;Tiberghien A.;Woo C.;Masterson L.;Stephenson M.;Hartley J.;Jenkins T.;Shnyder S.;Loadman P.;Waring M.;Thurston D. (2006) Journal of Medicinal Chemistry. 49, 5442-5461.
Volpato M.;Seargent J.;Loadman P.;Phillips R. (2005) European Journal of Cancer. Part A. 41, 1331-1338.
Seargent J.;Loadman P.;Martin S.;Naylor B.;Bibby M.;Gill J. (2005) Urology. 65, 815-820.
Phillips, Roger M.; Loadman, Paul M.; Maitland, Derek J.; Shnyder, Steven D.; Jaffar, M.; Steans, Gillian; Cooper, Patricia A.; Race, Amanda D.; Patterson, A.V.; Stratford, I.J. (2004)
Basu, Saurajyoti; Brown, John E.; Flannigan, G. Michael; Gill, Jason H.; Loadman, Paul M.; Martin, Sandie W.; Naylor, Brian; Puri, Rajiv; Scally, Andy J.; Seargent, Jill M.; Shah, Tariq K.; Phillips, Roger M. (2004)
Basu, Saurajyoti; Brown, John E.; Flannigan, G. Michael; Gill, Jason H.; Loadman, Paul M.; Naylor, Brian; Scally, Andy J.; Seargent, Jill M.; Shah, Tariq K.; Puri, Rajiv; Phillips, Roger M.; Martin, Sandie W. (2004)
Gill, Jason H.; Kirwan, Ian G.; Seargent, Jill M.; Martin, Sandie W.; Tijani, S.; Anikin, V.A.; Mearns, A.J.; Bibby, Michael C.; Anthoney, Alan; Loadman, Paul M. (2004)
Phillips R.;Basu S.;Brown J.;Flannigan G.;Loadman P.;Martin S.;Naylor B.;Puri R.;Shah T. (2004) International Journal of Oncology. 24, 1005-1010.
Wilkinson, Gary P.; Taylor, James P.; Shnyder, Steven D.; Loadman, Paul M.; Cooper, Patricia A.; Howard, P.W.; Thurston, D.E.; Jenkins, Terence C. (2004)
Kirwan, Ian G.; Loadman, Paul M.; Swaine, David J.; Anthoney, Alan; Pettit, G.R.; Lippert III, J.W.; Shnyder, Steven D.; Cooper, Patricia A.; Bibby, Michael C. (2004)
Suggitt M.;Fearnley J.;Swaine D.;Volpato M.;Phillips R.;Bibby M.;Loadman P.;Anderson D. (2003) Teratogenesis Carcinogenesis and Mutagenesis. Suppl 2, 13-29.
Rustin G.;Bradley C.;Galbraith S.;Stratford M.;Loadman P.;Waller S.;Bellenger K.;Gumbrell L.;Folkes L.;Halbert G. (2003) British Journal of Cancer. 88, 1160-1167.
Gibson, Paul; Gill, Jason H.; Khan, Parveen A.; Seargent, Jill M.; Martin, Sandie W.; Batman, Philip A.; Griffith, John; Bradley, C.; Double, John A.; Bibby, Michael C.; Loadman, Paul M. (2003)
Loadman P.;Bibby M.;Phillips R. (2002) British Journal of Pharmacology. 137, 701-709.
Loadman P.;Swaine D.;Bibby M.;Welham K.;Patterson L. (2001) Drug Metabolism and Disposition. 29, 422-426.
Phillips R.;Burger A.;Loadman P.;Jarrett C.;Swaine D.;Fiebig H. (2000) Cancer Research. 60, 6384-6390.
Swaine D.;Loadman P.;Bibby M.;Graham M.;Patterson L. (2000) Journal of Chromatography B: Biomedical Sciences and Applications. 742, 239-245.
Loadman P.;Phillips R.;Lim L.;Bibby M. (2000) Biochemical Pharmacology. 59, 831-837.
Grosios K.;Loadman P.;Swaine D.;Pettit G.;Bibby M. (2000) Anticancer Research. 20, 229-233.
Loadman P.;Bibby M.;Double J.;Al-Shakhaa W.;Duncan R. (1999) Clinical Cancer Research. 5, 3682-3688.
Calabrese C.;Loadman P.;Lim L.;Bibby M.;Double J.;Brown J.;Lamb J. (1999) Drug Metabolism and Disposition. 27, 240-245.
Moore A.;Loadman P.;Devine D.;Bibby M. (1995) Journal of Chromatography - Biomedical Applications. 672, 225-231.
Barnieh F.M.;Loadman P.M.;Falconer R.A. (2021) Current Research in Pharmacology and Drug Discovery.
Barnieh F.M.;Loadman P.M.;Falconer R.A. (2021) Biochimica et Biophysica Acta - Reviews on Cancer.
Jove M.;Spencer J.;Clench M.;Loadman P.;Twelves C. (2019) Critical Reviews in Oncology/Hematology.
Vandooren J.;Opdenakker G.;Loadman P.;Edwards D. (2016) Advanced Drug Delivery Reviews.
Bateson H.;Saleem S.;Loadman P.;Sutton C. (2011) Journal of Pharmacological and Toxicological Methods.
Loadman P.;Calabrese C. (2001) Journal of Chromatography B: Biomedical Sciences and Applications.
Picksley S.;Dart D.;Mansoor M.;Loadman P. (2001) Expert Opinion on Therapeutic Patents.