Preclinical Studies of Saponins for Tumor Therapy
Bachran C.;Bachran S.;Sutherland M.;Bachran D.;Fuchs H. (2015) Recent Advances in Medicinal Chemistry. 272-302.
Dr Mark Sutherland is a Lecturer in Biochemistry in the School of Chemistry and Biosciences, University of Bradford. After completing his MSc in Microbiology at the University of Stellenbosch, South Africa he worked for a few years as a school teacher and University Lecturer. He was offered a PhD at the Charite – Campus Benjamin Franklin, Berlin, Germany where he received his doctorate in Medical Biochemistry. He then worked for a number of years as a PDRA in Berlin in the field of immunotoxins. This work resulted in a number of publications, review articles and book chapters. In 2005 he moved to the Institute of Cancer Therapeutics at the University of Bradford. He carried out research for a number of projects within the Institute to generate proof-of-concept data for grant and patent applications. He also taught laboratory skills to MSc and PhD students, and lectured undergraduate and MSc students. His research was in the field of integrins as a target for new anti-cancer drugs in prostate cancer and melanoma, as well as the role of sialyltransferases in neuroblastoma. The research involves a wide range of methodologies including generating lentivirus knockout models (shRNA), development of an ELISA for biomarker analysis, protein expression/purification using GST-tagged protein in E.coli and luciferase reporter assays. This work has led to numerous publications, and successful grant applications. Dr Sutherland has vast experience in an array of Molecular Biology techniques including gene cloning, transformation/transfection, Western blotting, PCR and qPCR; as well as managing the Molecular Biology Laboratory. He started his current role as Lecturer in January 2019.
Bachran C.;Bachran S.;Sutherland M.;Bachran D.;Fuchs H. (2015) Recent Advances in Medicinal Chemistry. 272-302.
Asiye Busra Boz Er;Helen M Sheldrake;Mark Sutherland (2024) International Journal of Molecular Sciences. 25
Mark Sutherland, Andrew Gordon, Fatemah OFO Al-Shammari, Adam Throup, Amy Cilia La Corte, Helen Philippou, Steven D Shnyder, Laurence H Patterson, Helen M Sheldrake (2023) Cancers. 15
El-Tanani M;Platt-Higgins A;Lee YF;Al Khatib AO;Haggag Y;Sutherland M;Zhang SD;Aljabali AAA;Mishra V;Serrano-Aroca Á;Tambuwala MM;Rudland PS; (2022) Life Sciences. 310
Presa D;Khurram SA;Zubir AZA;Smarakan S;Cooper PA;Morais GR;Sadiq M;Sutherland M;Loadman PM;McCaul J;Shnyder SD;Patterson LH;Pors K; (2021) Scientific Reports. 11
Ehrit, J.; Keys, T.G.; Sutherland, Mark H.; Wolf, S.; Meier, C.; Falconer, R.A.; Gerardy-Schahn, R. (2017) ChemBioChem. 18, 1332-1337.
Elkashef, Sara M.; Sutherland, Mark H.; Patterson, Laurence H.; Loadman, Paul M.; Falconer, Robert A. (2016) ANALYST (PRINT). 141, 5849-5856.
Vinader, Victoria; Sadiq, Maria; Sutherland, Mark H.; Huang, M.Y.; Loadman, Paul M.; Elsalem, Lina M.I.; Shnyder, Steven D.; Cui, H.J.; Afarinkia, Kamyar; Searcey, M.; Patterson, Laurence H.; Pors, Klaus (2015) MedChemComm. 6, 187-191.
Sheldrake, Helen M.; Travica, S.; Johansson, I.; Loadman, Paul M.; Sutherland, Mark H.; Elsalem, Lina M.I.; Illingworth, Nicola A.; Cresswell, Alexander J.; Reuillon, Tristan; Shnyder, Steven D.; Mkrtchian, S.; Searcey, M.; Ingelman-Sundberg, M.; Patterson, Laurence H.; Pors, Klaus (2013)
Al-Saraireh, Yousef M.J.; Sutherland, Mark H.; Springett, Bradley R.; Freiberger, F.; Ribeiro Morais, Goreti; Loadman, Paul M.; Errington, R.J.; Smith, P.J.; Fukuda, M.; Gerardy-Schahn, R.; Patterson, Laurence H.; Shnyder, Steven D.; Falconer, Robert A. (2013) PLoS ONE. 8
Sutherland, Mark H.; Gill, Jason H.; Loadman, Paul M.; Laye, Jonathan P.; Sheldrake, Helen M.; Illingworth, Nicola A.; Alandas, Mohammed N.; Cooper, Patricia A.; Searcey, M.; Pors, Klaus; Shnyder, Steven D.; Patterson, Laurence H. (2013)
Bachran C.;Schneider S.;Riese S.;Bachran D.;Urban R.;Schellmann N.;Zahn C.;Sutherland M.;Fuchs H. (2011) Life Sciences. 88, 226-232.
Pors, Klaus; Loadman, Paul M.; Shnyder, Steven D.; Sutherland, Mark H.; Sheldrake, Helen M.; Guino, M.; Kiakos, K.; Hartley, J.A.; Searcey, M.; Patterson, Laurence H. (2011)
Sutton C.;Sutherland M.;Shnyder S.;Patterson L. (2010) Proteomics. 10, 327-331.
Fuchs H;Bachran D;Panjideh H;Schellmann N;Weng A;Melzig MF;Sutherland M;Bachran C; (2009) Current Drug Targets. 10
Bachran C;Dürkop H;Sutherland M;Bachran D;Müller C;Weng A;Melzig MF;Fuchs H; (2009) Journal of immunotherapy (Hagerstown, Md. : 1997). 32
Bachran C;Bachran S;Sutherland M;Bachran D;Fuchs H; (2008) Mini-Reviews in Medicinal Chemistry. 8
Bachran C;Sutherland M;Bachran D;Fuchs H; (2007) Recent Patents on Drug Delivery and Formulation. 1
Bachran C.;Sutherland M.;Bachran D.;Fuchs H. (2007) Clinical Chemistry. 53, 1676-1683.
Fuchs H;Bachran C;Li T;Heisler I;Dürkop H;Sutherland M; (2007) Journal of Controlled Release. 117
Bachran C.;Sutherland M.;Heisler I.;Hebestreit P.;Melzig M.;Fuchs H. (2006) Experimental Biology and Medicine. 231, 412-420.
Heisler I;Sutherland M;Bachran C;Hebestreit P;Schnitger A;Melzig MF;Fuchs H; (2005) Journal of Controlled Release. 106
Bachran C;Heisler I;Fuchs H;Sutherland M; (2005) Biochemical and Biophysical Research Communications. 337
Heisler I;Keller J;Tauber R;Sutherland M;Fuchs H; (2003) International Journal of Cancer. 103
Heisler I;Keller J;Tauber R;Sutherland M;Fuchs H; (2002) Analytical Biochemistry. 302
Sutherland M;Shankaranarayanan P;Schewe T;Nigam S; (2001) Biochemical Journal. 353
Nigam S;Kumar GS;Sutherland M;Schewe T;Ikawa H;Yamasaki Y;Ueda N;Yamamoto S; (1999) International Journal of Cancer. 82
Sutherland M.;Gordon A.;Shnyder S.;Patterson L.;Sheldrake H. (2012) Cancers.
Fuchs H.;Bachran D.;Panjideh H.;Schellmann N.;Weng A.;Melzig M.;Sutherland M.;Bachran C. (2009) Current Drug Targets.
Bachran C.;Bachran S.;Sutherland M.;Bachran D.;Fuchs H. (2008) Mini-Reviews in Medicinal Chemistry.