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Dr. Ibrahim Khot

Academic

Area
School of Chemistry & Biosciences
Faculty of Life Sciences
E-mail
Dr. Ibrahim Khot

Biography

Dr. Ibrahim Khot was appointed as Assistant Professor in Biochemistry within the School of Chemistry and Biosciences in 2023. Prior to this Ibrahim was a lecturer at the University of Leeds and completed his Postdoctoral Research Fellowship within the Schools of Medicine and Physics & Astronomy at the University of Leeds and his research was funded by Leeds NIHR BRC, UKRI EPSRC, Wellcome Trust, The Royal Society and Bowel Cancer UK. In 2013, he completed a BSc with First Class honours in Biomedical Sciences and in 2014, completed an MSc with Distinction in Cancer Pharmacology, both from the University of Bradford. He then undertook his doctoral studies at the University of Leeds, earning a PhD in Medicine and Biology in 2019. Ibrahim’s research focus is pre-clinical evaluation and clinical translational of novel cancer technologies, focussing on the development of cutting-edge patient-derived cancer organoids to study the impact of biofilms in bowel cancers and to develop personalised treatments. His research experience also extends to developing multimodal nanoparticles to fluorescently image and deliver photodynamic therapy to treat bowel cancers. This is in conjunction with the use of complex in vitro cell models of cancer, specifically three-dimensional cell cultures and state-of-the-art patient-derived organoids. Ongoing multi-collaborative research includes the development of high-throughput microfluidic platforms for therapeutic screening applications and miniature implantable LED devices to deliver metronomic photodynamic therapies. Through his research career, Ibrahim has developed multiple academic and industrial collaborators on different projects. Outputs from Ibrahim’s research includes multiple high impact publications, conference presentations, grant funding and a patent on wireless LED technologies. For academic appointments, Ibrahim has lectured on different undergraduate and postgraduate biology and medicine programmes and serves as primary supervisor to a cohort of postgraduate research students including MD, PhD, MRes, MSc and BSc students. He also serves as internal and external university examiner for doctoral transfer and final thesis examinations.

Research

Research projects

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Royal College of Surgeons of England

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Leeds Biomedical Research Centre

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University of Leeds

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Engineering and Physical Sciences Research Council

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Royal Society

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University of Bradford

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University of Bradford

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Wellcome Trust

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Pathological Society of Great Britain and Ireland

award

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Bowel Cancer UK

award

Research collaborator

  • Professor David Jayne (University of Leeds)
  • Professor Stephen Evans (University of Leeds)
  • Mr Ryan Mathew (University of Leeds)
  • Professor Nikil Kapur (University of Leeds)
  • Professor Masahiro Inoue (Kyoto University)
  • Professor John Ladbury (University of Leeds)
  • Professor Mark Green (Kings College London)
  • Dr Sung Il Park (ShanghaiTech University)

Teaching

Modules

  • Clinical and Analytical Biochemistry - BIS5013-B
  • MSc Research Project - BIS7026-E

Professional activities

  • University Recognition Scheme Award (1 February 2022)
  • Wellcome Trust Visiting Researcher Fellowship (1 April 2019)

  • University of Leeds - Fellowship of the Higher Education Academy (FHEA)
  • University of Leeds - PhD in Medicine (1 October 2015)
  • University of Bradford - MSc Cancer Pharmacology (1 October 2013)
  • University of Bradford - BSc (Hons) Biomedical Sciences (1 September 2010)

  • University of Bradford - Assistant Professor in Biochemistry (1 August 2023)
  • University of Leeds - Lecturer and Research Fellow (1 October 2020)
  • University of Leeds - Lecturer (1 October 2020)
  • University of Leeds - Research Fellow (1 October 2018)
  • University of Leeds - Postdoctoral Researcher (1 October 2018)

  • Visiting Research Fellow: Kyoto University Kyoto JP Graduate School of Medicine (1 April 2019)

  • U.S. Patent Application No. 63/417,040 - Biocompatible, miniaturized dual-channel wireless optoelectronics for photodynamic therapy (18 October 2022)

  • Institute of Biomedical Sciences , Fellow (FIBMS)
  • Royal Society of Biology, Chartered Biologist (CBiol)
  • Royal Society of Biology, Member (MRSB)
  • Royal Society of Medicine, Member

Publications