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Professor Krzysztof Poterlowicz

Professor

Faculty/Dept/School School of Chemistry and Bioscience
(Faculty of Life Sciences)
Emailk.poterlowicz1@bradford.ac.uk
Telephone +441274 234737

Biography

Professor of Bioinformatics and Biomedical Data Science interested in advancing FAIR data management and computational method in biomedical domain through research and training.

Director of Research for Computational and Data Driven Science at Faculty of Life Science, University of Bradford https://www.bradford.ac.uk/life-sciences/research-and-innovation/computational-and-data-driven-scien...

ELIXIR UK Training Co-ordinator and Principal Investigator on UKRI funded ELIXIR-UK DaSH Fellowship that aims to create culture change with fellows producing and delivering FAIR data stewardship training and acting as ambassadors to embed research data management in their organisations https://elixiruknode.org/projects/elixir-uk-dash/

Research

My primary research focus revolves around the development and training of FAIR data management and computational methods within the biomedical domain.

Recent projects include:

  • ELIXIR-UK: FAIR Data Stewardship training

  • Reference hCNV datasets, use-case workflows and benchmarking
  • Predicting therapy responses in psoriasis
Current team members:

Current postgraduate research students:

  • Katarzyna Kaminiecka
  • Wafa Alsahly
  • Sirli Anniko
  • Sumaia Sabouni
  • Cheralynn (Shelly) Saunders
  • Isabel Hyde (with University of Leeds)

Publications

TitleCellular sheddases are induced by Merkel cell polyomavirus small tumour antigen to mediate cell dissociation and invasiveness (2019)
AuthorsNwogu, N.; Boyne, James R.; Dobson, S.J.; Poterlowicz, Krzysztof; Blair, G.E.; Macdonald, A.; Mankouri, J.; Whitehouse, A.
 
TitleInterplay of MicroRNA-21 and SATB1 in Epidermal Keratinocytes during Skin Aging. (2019)
AuthorsAhmed MI;Pickup ME;Rimmer AG;Alam M;Mardaryev AN;Poterlowicz K;Botchkareva NV;Botchkarev VA;
JournalJournal of Investigative Dermatology
DOI10.1016/j.jid.2019.04.022
 
TitleThe cellular chloride channels CLIC1 and CLIC4 contribute to virus-mediated cell motility (2018)
AuthorsStakaityte, G.; Nwogu, N.; Lippiat, J.D.; Blair, G.E.; Poterlowicz, Krzysztof; Boyne, James R.; Macdonald, A.; Mankouri, J.; Whitehouse, A.
 
TitleMCV-miR-M1 targets the host-cell immune response resulting in the attenuation of neutrophil chemotaxis (2018)
AuthorsAkhbari, Pouria; Tobin, Desmond J.; Poterlowicz, Krzysztof; Roberts, W.; Boyne, James R.
 
Title5C analysis of the Epidermal Differentiation Complex locus reveals distinct chromatin interaction networks between gene-rich and gene-poor TADs in skin epithelial cells (2017)
AuthorsPoterlowicz K.;Yarker J.;Malashchuk I.;Lajoie B.;Mardaryev A.;Gdula M.;Sharov A.;Kohwi-Shigematsu T.;Botchkarev V.;Fessing M.
JournalPLoS Genetics
DOI10.1371/journal.pgen.1006966
 
Titlep63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes (2017)
AuthorsRapisarda V.;Malashchuk I.;Asamaowei I.;Poterlowicz K.;Fessing M.;Sharov A.;Karakesisoglou I.;Botchkarev V.;Mardaryev A.
JournalJournal of Investigative Dermatology
DOI10.1016/j.jid.2017.05.013
 
TitleInhibition of HOX/PBX dimer formation leads to necroptosis in acute myeloid leukemia cells (2017)
AuthorsAlharbi, R.A.; Pandha, H.S.; Simpson, G.R.; Pettengell, R.; Poterlowicz, Krzysztof; Thompson, A.; Harrington, K.J.; El-Tanani, Mohamed; Morgan, Richard
 
Titlep63 transcription factor regulates nuclear shape and expression of nuclear envelope-associated genes in epidermal keratinocyte (2017)
AuthorsRapisarda, Valentina; Malashchuk, Igor; Asamaowei, Inemo E.; Poterlowicz, Krzysztof; Fessing, Michael Y.; Sharov, A.A.; Karakesisoglou, I.; Botchkarev, Vladimir A.; Mardaryev, Andrei N.
 
TitleCbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium (2016)
AuthorsMardaryev, Andrei N.; Liu, B.; Rapisarda, Valentina; Poterlowicz, Krzysztof; Malashchuk, Igor; Rudolf, Jana; Sharov, A.A.; Jahoda, C.J.; Fessing, Michael Y.; Benitah, S.; Xu, G.; Botchkarev, Vladimir A.
 
TitleCirculating tumour DNA: a minimally invasive biomarker for tumour detection and stratification (2016)
AuthorsSurani, Arif A.; Poterlowicz, Krzysztof
 
TitleMicroRNA-214 controls skin and hair follicle development by modulating the activity of the Wnt pathway (2014)
AuthorsAhmed, Mohammed I.; Alam, Majid A.; Emelianov, V.U.; Poterlowicz, Krzysztof; Patel, Ankit; Sharov, A.A.; Mardaryev, Andrei N.; Botchkareva, Natalia V.
 
TitleComplex Changes in the Apoptotic and Cell Differentiation Programs during Initiation of the Hair Follicle Response to Chemotherapy (2014)
AuthorsSharova, T.Y.; Poterlowicz, Krzysztof; Botchkareva, Natalia V.; Kondratiev, N.A.; Aziz, A.; Spiegel, J.H.; Botchkarev, Vladimir A.; Sharov, A.A.
 
Titlep63 and Brg1 control developmentally regulated higher-order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cells (2014)
AuthorsMardaryev, Andrei N.; Gdula, Michal R.; Yarker, Joanne L.; Emelianov, V.U.; Poterlowicz, Krzysztof; Sharov, A.A.; Sharova, T.Y.; Scarpa, J.A.; Chambon, P.; Botchkarev, Vladimir A.; Fessing, Michael Y.
 
TitleBone morphogenetic protein signaling suppresses wound-induced skin repair by inhibiting keratinocyte proliferation and migration (2014)
AuthorsLewis, Christopher J.; Mardaryev, Andrei N.; Poterlowicz, Krzysztof; Sharova, T.Y.; Aziz, A.; Sharpe, David T.; Botchkareva, Natalia V.; Sharov, A.A.
 
TitleRemodeling of Three-Dimensional Organization of the Nucleus during Terminal Keratinocyte Differentiation in the Epidermis (2013)
AuthorsGdula, Michal R.; Poterlowicz, Krzysztof; Mardaryev, Andrei N.; Sharov, A.A.; Fessing, Michael Y.; Botchkarev, Vladimir A.; Peng, Yonghong
 
TitleGenome organizing function of SATB1 in tumor progression. (2013)
AuthorsKohwi-Shigematsu, T.; Poterlowicz, Krzysztof; Ordinario, E.; Han, H.J.; Botchkarev, Vladimir A.; Kohwi, Y.
 
TitleCigarette smoke-induced transgenerational alterations in genome stability in cord blood of human F1 offspring (2012)
AuthorsLaubenthal, Julian; Zlobinskaya, O.; Poterlowicz, Krzysztof; Baumgartner, Adolf; Gdula, Michal R.; Fthenou, E.; Keramarou, M.; Hepworth, S.J.; Kleinjans, J.C.; van Schooten, F.J.; Brunborg, G.; Godschalk, R.W.; Schmid, Thomas E.; Anderson, Diana
 
TitleCharacterization of Changes in the Proteome in Different Regions of 3D Multicell Tumor Spheroids (2012)
AuthorsMcMahon, Kelly M.; Volpato, Milène; Chi, H.Y.; Musiwaro, P.; Poterlowicz, Krzysztof; Peng, Yonghong; Scally, Andy J.; Patterson, Laurence H.; Phillips, Roger M.; Sutton, Chris W.
 
Titlep63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis (2011)
AuthorsFessing, Michael Y.; Mardaryev, Andrei N.; Gdula, Michal R.; Sharov, A.A.; Sharova, T.Y.; Rapisarda, Valentina; Gordon, K.B.; Smorodchenko, A.D.; Poterlowicz, Krzysztof; Ferone, G.; Kohwi, Y.; Missero, C.; Kohwi-Shigematsu, T.; Botchkarev, Vladimir A.
 
TitleLhx2 differentially regulates Sox9, Tcf4 and Lgr5 in hair follicle stem cells to promote epidermal regeneration after injury (2011)
AuthorsMardaryev, Andrei N.; Meier, N.; Poterlowicz, Krzysztof; Sharov, A.A.; Sharova, T.Y.; Ahmed, Mohammed I.; Rapisarda, Valentina; Lewis, Christopher J.; Fessing, Michael Y.; Ruenger, T.M.; Bhawan, J.; Werner, S.; Paus, R.; Botchkarev, Vladimir A.
 
TitleBMP signaling induces cell-type-specific changes in gene expression programs of human keratinocytes and fibroblasts (2010)
AuthorsFessing, Michael Y.; Atoyan, R.; Shander, B.; Mardaryev, Andrei N.; Botchkarev, V.V. Jr; Poterlowicz, Krzysztof; Peng, Yonghong; Efimova, T.; Botchkarev, Vladimir A.