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Professor Colin Wright,
Professor of Pharmacognosy

Information about Professor Colin Wright at the University of Bradford.

School of Pharmacy & Medical Sciences
(Faculty of Life Sciences)
+44 1274 234739
Photo of Professor Colin Wright


I started my career as a hospital pharmacist and became interested in tropical diseases as well as traditional medicine while working as a pharmacist in India (1980-1982). This led to my long-term interest in pharmacognosy and research in traditional medicines used in the treatment of infectious diseases and cancer. I have taught pharmacognosy for more than 20 years with the principal aims of highlighting the importance of natural products in medicine & drug discovery as well as revealing their fascinating chemistry and pharmacological effects. When I started at Bradford School of Pharmacy in 1994, the teaching of Pharmacognosy was fairly traditional including analytical microscopy. Working with Dr Peter Linley, I developed this subject area to provide modules that were more relevant to modern pharmacy practice by illustrating through lectures and lab workshops why a knowledge of herbal medicines and natural products is necessary for the practising pharmacist. Similarly, I developed a module on natural products for the (former) M.Sc in Pharmaceutical Services and Medicines Control. Although pharmacognosy as a subject is no longer in the new pharmacy curriculum, I have been able to include some content e.g. in unit FS2 which includes the origins of drugs and eco-pharmacy and a number of applications exercises present problems involving herbal medicines/natural products. Also, herbal medicines is a topic for student selected components and I offer natural product-related laboratory research projects. My research has focussed mainly on the investigation of traditional medicines used for the treatment of malaria with the aim of identifying lead antimalarial compounds. In collaboration with Bradford’s Institute for Cancer Research I have also investigated plants including marine algae (seaweeds) for their potential to yield anticancer compounds. I also have an interest in anti-TB natural products. My main research achievement has been the study of cryptolepine for which I received funding from WHO and is described in more detail below. I have successfully supervised 20 PhD students whose work, together with the help of many collaborators has resulted in the publication of 98 research papers and more than 100 conference contributions. In addition, I am regularly invited to present my research at conferences and seminars. I actively participate in two of the research groups in the School of Pharmacy especially in the Medicines Development and Pharmaceutical Science group in which I line manage 7 academic staff and have a role in facilitating the group’s research ambitions and strategy.


There are 94 publications involving or that are attributed to Professor Colin Wright.

Peer Reviewed Journal

Professor Colin Wright has 94 publication(s) listed under peer reviewed journal.
Title Year Publication name Journal Volume Pages Authors Editors ISSN Publisher DOI Location
The antimalarial and cytotoxic drug cryptolepine intercalates into DNA at cytosine-cytosine sites. 2001 Lisgarten, J.N.; Coll, M.; Portugal, J.; Wright, Colin W.; Aymami, J.
Antiprotozoal activities of Centipeda minima 1994 Phytotherapy Research 8 436 - 438 Yu H.;Wright C.;Cai Y.;Yang S.;Phillipson J.;Kirby G.;Warhurst D. 0951-418X 10.1002/ptr.2650080713
Alkaloids from Narcissus cantabricus 1995 Phytochemistry 40 1549 - 1551 Bastida J.;Contreras J.;Codina C.;Wright C.;David Phillipson J. 0031-9422 10.1016/0031-9422(95)00448-G
Toward the chemical ecology of medicinal plant use in chimpanzees: The case of Vernonia amygdalina, a plant used by wild chimpanzees possibly for parasite-related diseases 1994 Journal of Chemical Ecology 20 541 - 553 Ohigashi H.;Huffman M.;Izutsu D.;Koshimizu K.;Kawanaka M.;Sugiyama H.;Kirby G.;Warhurst D.;Allen D.;Wright C.;David Phillipson J.;Timon-David P.;Delmas F.;Elias R.;Balansard G. 0098-0331 10.1007/BF02059596
Selective antiprotozoal activity of some Strychnos alkaloids 1994 Phytotherapy Research 8 149 - 152 Wright C.;Allen D.;Cai Y.;Chen Z.;Phillipson J.;Kirby G.;Warhurst D.;Tits M.;Angenot L. 0951-418X 10.1002/ptr.2650080306
In vitro antiplasmodial, antiamoebic, and cytotoxic activities of a series of bisbenzylisoquinoline alkaloids 1994 Antimicrobial Agents and Chemotherapy 38 96 - 103 Marshall S.;Russell P.;Wright C.;Anderson M.;Phillipson J.;Kirby G.;Warhurst D.;Schiff P. 0066-4804 10.1128/AAC.38.1.96
Alkaloids from Cephaelis dichroa 1993 Phytochemistry 33 1117 - 1119 Solis P.;Wright C.;Gupta M.;Phillipson J. 0031-9422 10.1016/0031-9422(93)85033-N
Alstonia species: are they effective in malaria treatment? 1993 Journal of Ethnopharmacology 40 41 - 45 Wright C.;Allen D.;Phillipson J.;Kirby G.;Warhurst D.;Massiot G.;Le Men-Olivier L. 0378-8741 10.1016/0378-8741(93)90087-L
A microwell cytotoxicity assay using Artemia salina (brine shrimp) 1993 Planta Medica 59 250 - 252 Solis P.;Wright C.;Anderson M.;Gupta M.;Phillipson J. 0032-0943
Quassinoids Exhibit Greater Selectivity Against Plasmodium Falciparum Than Against Entamoeba Histolytica, Giardia Intestinalis Or Toxoplasma Gondii In Vitro 1993 Journal of Eukaryotic Microbiology 40 244 - 246 WRIGHT C.;ANDERSON M.;ALLEN D.;PHILLIPSON J.;KIRBY G.;WARHURST D.;CHANG H. 1066-5234 10.1111/j.1550-7408.1993.tb04910.x
In vitro antimalarial and cytotoxic activities of semisynthetic derivatives of brusatol 1993 European Journal of Medicinal Chemistry 28 265 - 269 Allen D.;Toth I.;Wright C.;Kirby G.;Warhurst D.;Phillipson J. 0223-5234 10.1016/0223-5234(93)90143-3
Determination of anti-giardial activity in vitro by means of soluble formazan production 1992 Transactions of the Royal Society of Tropical Medicine and Hygiene 86 517 - 519 Wright C.;Melwani S.;David Phillipson J.;Warhurst D. 0035-9203 10.1016/0035-9203(92)90093-R
Parasitological and microbiological evaluation of Mixe Indian medicinal plants (Mexico). 1992 Journal of Ethnopharmacology 36 Heinrich M;Kuhnt M;Wright CW;Rimpler H;Phillipson JD;Schandelmaier A;Warhurst DC; 0378-8741
In vitro antiamoebic and antiplasmodial activities of alkaloids isolated from Alstonia angustifolia roots 1992 Phytotherapy Research 6 121 - 124 Wright C.;Allen D.;Cai Y.;Phillipson J.;Said I.;Kirby G.;Warhurst D. 0951-418X 10.1002/ptr.2650060303
A new alkaloid from the roots of alstonia angustifolia 1992 Journal of Natural Products 55 1323 - 1324 Said I.;Din L.;Yusoff N.;Wright C.;Cai Y.;Phillipson J. 0163-3864 10.1021/np50087a025
Molecular modelling of usambarensine, tubulosine and emetine, three cytotoxic amoebicide alkaloids 1991 Journal de Pharmacie de Belgique 46 85 - 92 Quetin-Leclercq J.;Dupont L.;Wright C.;Phillipson J.;Warhurst D.;Angenot L. 0047-2166
Can ethnopharmacology contribute to the development of antimalarial agents? 1991 Journal of Ethnopharmacology 32 155 - 165 David Phillipson J.;Wright C. 0378-8741 10.1016/0378-8741(91)90113-R
Antiamoebic and antiplasmodial activities of alkaloids isolated from Strychnos usambarensis. 1991 Planta Medica 57 Wright CW;Bray DH;O'Neill MJ;Warhurst DC;Phillipson JD;Quetin-Leclercq J;Angenot L; 0032-0943 10.1055/s-2006-960112
Plants as sources of antimalarial drugs, part 6: Activities of Simarouba amara fruits 1988 Journal of Ethnopharmacology 22 183 - 190 O'Neill M.;Bray D.;Boardman P.;Wright C.;David Phillipson J.;Warhurst D.;Gupta M.;Correya M.;Solis P. 0378-8741 10.1016/0378-8741(88)90126-2
Use of microdilution to assess in vitro antiamoebic activities of Brucea javanica fruits, Simarouba amara stem, and a number of quassinoids. 1988 Antimicrobial Agents and Chemotherapy 32 Wright CW;O'Neill MJ;Phillipson JD;Warhurst DC; 0066-4804
Pharmacy Education: Understanding drug abuse 1993 Pharmaceutical Journal 250 Wright, C.W.
A cytotoxic diterpenoid from Croton membranaceus, the major constituent of anticancer herbal formulations used in Ghana 2008 Natural product communications Bayor, M.T.;Ayim, J.S.K.;Marston, G.;Phillips, R.M.;Shnyder, S.D.;Wheelhouse, R.T.;Wright, C.W.;
In-vitro cytotoxicity and thermodenaturation studies for cryptolepine and analogues 2000 Journal of Pharmacy and Pharmacology 52 109 Gokcek Y.;Pollet P.;Wright C.;Brown J. 0022-3573
In-vitro antimycobacterial screening of some plant species used in traditional medicine for the treatment of tuberculosis 2000 Journal of Pharmacy and Pharmacology 52 310 Newton S.;Lau C.;Wright C. 0022-3573
Antimalarial ethnobotany: In vitro antiplasmodial activity of seven plants identified in the Nigerian Middle Belt 2004 Pharmaceutical Biology 42 588 - 591 Ajaiyeoba E.;Ashidi J.;Abiodun O.;Okpako L.;Ogbole O.;Akinboye D.;Falade C.;Bolaji O.;Gbotosho G.;Falade M.;Itiola O.;Houghton P.;Wright C.;Oduola A. 1388-0209 10.1080/13880200490902455
Antiplasmodial principles from Cassia nigricans 2004 Pharmaceutical Biology 42 626 - 628 Obodozie O.;Okpako L.;Tarfa F.;Orisadipe A.;Okogun J.;Inyang U.;Ajaiyeoba E.;Wright C. 1388-0209 10.1080/13880200490902545
Screening indian plant species for antiplasmodial properties - Ethnopharmacological compared with random selection 2012 Phytotherapy Research 26 1793 - 1799 Kantamreddi V.;Wright C. 0951-418X 10.1002/ptr.4651
In vitro anti-plasmodial and cytotoxic activities of plants used as antimalarial agents in the southwest Nigerian ethnomedicine 2005 Journal of Natural Remedies 5 1 - 6 Ajaiyeoba E.;Bolaji O.;Akinboye D.;Falade C.;Gbotosho G.;Ashidi J.;Okpako L.;Oduola O.;Falade M.;Itiola O.;Houghton P.;Wright C.;Ogundahunsi O.;Oduola A. 0972-5547
Isolation and in vitro antiplasmodial activities of alkaloids from Teclea trichocarpa: In vivo antimalarial activity and x-ray crystal structure of normelicopicine 2002 Journal of Natural Products 65 956 - 959 Muriithi M.;Abraham W.;Addae-Kyereme J.;Scowen I.;Croft S.;Gitu P.;Kendrick H.;Njagi E.;Wright C. 0163-3864 10.1021/np0106182
Antiplasmodial and antiamoebic activities of medicinal plants from Sierra Leone 2000 Phytotherapy Research 14 356 - 358 Marshall S.;Russell P.;Phillipson J.;Kirby G.;Warhurst D.;Wright C. 0951-418X 10.1002/1099-1573(200008)14:5<356::AID-PTR636>3.0.CO;2-Z
Huprines as a new family of dual acting trypanocidal-antiplasmodial agents 2011 Bioorganic and Medicinal Chemistry 19 1702 - 1707 Defaux J.;Sala M.;Formosa X.;Galdeano C.;Taylor M.;Alobaid W.;Kelly J.;Wright C.;Camps P.;Muñoz-Torrero D. 0968-0896 10.1016/j.bmc.2011.01.028
Evaluation of Some Egyptian Plant Species for in vitro Antimycobacterial and Cytotoxic Activities 2003 Pharmaceutical Biology 41 463 - 465 Abou El Seoud K.;Bibby M.;Shoeib N.;Wright C. 1388-0209 10.1076/phbi.41.6.463.17831
Correlation of hyperforin content of Hypericum perforatum (St John's Wort) extracts with their effects on alcohol drinking in C57BL/6J mice: A preliminary study 2003 Journal of Psychopharmacology 17 403 - 408 Wright C.;Gott M.;Grayson B.;Hanna M.;Smith A.;Sunter A.;Neill J. 0269-8811 10.1177/0269881103174018
Pterocarpans phaseollin and neorautenol isolated from Erythrina addisoniae induce apoptotic cell death accompanied by inhibition of ERK phosphorylation 2007 Toxicology 242 71 - 79 Wätjen W.;Kulawik A.;Suckow-Schnitker A.;Chovolou Y.;Rohrig R.;Ruhl S.;Kampkötter A.;Addae-Kyereme J.;Wright C.;Passreiter C. 0300-483X 10.1016/j.tox.2007.09.010
Low temperature X-ray crystallographic structure of the antiplasmodial compound 5-N-hydroxyethanequindoline hydrochloride 0.5CH3OH 2011 Journal of Chemical Crystallography 41 1757 - 1762 Hampson H.;Ho C.;Palmer R.;Potter B.;Helliwell M.;Wright C. 1074-1542 10.1007/s10870-011-0169-5
Structure of the tetraphenyl borate complex of the indoloquinoline alkaloid cryptolepine 1999 Journal of Chemical Crystallography 29 449 - 455 Wright C.;Philpson J.;Lisgarten J.;Palmer R. 1074-1542 10.1023/A:1009519211938
Antiplasmodial activities of some Ghanaian plants traditionally used for fever/malaria treatment and of some alkaloids isolated from Pleiocarpa mutica; in vivo antimalarial activity of pleiocarpine 2001 Journal of Ethnopharmacology 76 99 - 103 Addae-Kyereme J.;Croft S.;Kendrick H.;Wright C. 0378-8741 10.1016/S0378-8741(01)00212-4
Sesquiterpene lactones from Neurolaena oaxacana 1999 Journal of Natural Products 62 1093 - 1095 Passreiter C.;Sandoval-Ramirez J.;Wright C. 0163-3864 10.1021/np990038t
Seasonal variation in bromophenol content of Polysiphonia lanosa 2006 Natural product communications 1 47 - 49 Shoeib N.;Bibby M.;Blunden G.;Linley P.;Swaine D.;Wright C. 1934-578X
The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis 2002 Journal of Ethnopharmacology 79 57 - 67 Newton S.;Lau C.;Gurcha S.;Besra G.;Wright C. 0378-8741 10.1016/S0378-8741(01)00350-6
Synthesis of cryptolepine analogues as potential bioreducible anticancer agents 2007 Bioorganic and Medicinal Chemistry 15 6353 - 6360 Seville S.;Phillips R.;Shnyder S.;Wright C. 0968-0896 10.1016/j.bmc.2007.06.062
In-vitro antiplasmodial and cytotoxic activities of some British species of marine algae 2000 Journal of Pharmacy and Pharmacology 52 311 Shoeib N.;Bibby M.;Cooper P.;Blunden G.;Wright C. 0022-3573
Synthetic cryptolepine inhibits DNA binding of NF-κB 2007 Bioorganic and Medicinal Chemistry 15 43 - 49 Olajide O.;Heiss E.;Schachner D.;Wright C.;Vollmar A.;Dirsch V. 0968-0896 10.1016/j.bmc.2006.10.018
The antimalarial and cytotoxic drug cryptolepine intercalates into dna at cytosine-cytosine sites 2002 Nature Structural Biology 9 57 - 60 Lisgarten J.;Coll M.;Portugal J.;Wright C.;Aymami J. 1072-8368 10.1038/nsb729
Cryptolepine hydrochloride: A potent antimycobacterial alkaloid derived from Cryptolepis sanguinolenta 2003 Phytotherapy Research 17 434 - 436 Gibbons S.;Fallah F.;Wright C. 0951-418X 10.1002/ptr.1284
Enhancement of the Antiplasmodial Activity of Quassin by Transformation into a γ-Lactone 2003 Journal of Natural Products 66 1486 - 1489 Lang'at-Thoruwa C.;Kirby G.;Phillipson J.;Warhurst D.;Watt R.;Wright C. 0163-3864
Synthesis and antiplasmodial activities of some halogenated cryptolepine derivatives 2000 Journal of Pharmacy and Pharmacology 52 296 Wright C.;Addae-Kyereme J.;Brown J.;Cox M.;Gokcek Y.;Pollet P. 0022-3573
Synthesis of novel halogenated cryptolepine analogues 2006 Journal of Heterocyclic Chemistry 43 171 - 175 Gouni S.;Carrington S.;Wright C. 0022-152X 10.1002/jhet.5570430126
In vitro antiplasmodial, antiamoebic, and cytotoxic activities of some monomeric isoquinoline alkaloids 2000 Journal of Natural Products 63 1638 - 1640 Wright C.;Marshall S.;Russell P.;Anderson M.;Phillipson J.;Kirby G.;Warhurst D.;Schiff J. 0163-3864 10.1021/np000144r
Recent developments in naturally derived antimalarials: Cryptolepine analogues 2007 Journal of Pharmacy and Pharmacology 59 899 - 904 Wright C. 0022-3573 10.1211/jpp.59.6.0017
Genomewide expression profiling of cryptolepine-induced toxicity in Saccharomyces cerevisiae 2008 Antimicrobial Agents and Chemotherapy 52 3844 - 3850 Rojas M.;Wright C.;Piña B.;Portugal J. 0066-4804 10.1128/AAC.00532-08
In-vitro cytotoxic activities of the major bromophenols of the red alga Polysiphonia lanosa and some novel synthetic isomers 2004 Journal of Natural Products 67 1445 - 1449 Shoeib N.;Bibby M.;Blunden G.;Linley P.;Swaine D.;Wheelhouse R.;Wright C. 0163-3864 10.1021/np0305268
Phytochemistry and preliminary biological evaluation of Cyathostemma argenteum, a Malaysian plant used traditionally for the treatment of breast cancer 2004 Phytotherapy Research 18 507 - 510 Khamis S.;Bibby M.;Brown J.;Cooper P.;Scowen I.;Wright C. 0951-418X 10.1002/ptr.1318
Investigation of Indian Diospyros species for antiplasmodial properties 2008 Evidence-based Complementary and Alternative Medicine 5 187 - 190 Kantamreddi V.;Wright C. 1741-427X 10.1093/ecam/nem019
Identification of cryptolepine metabolites in rat and human hepatocytes and metabolism and pharmacokinetics of cryptolepine in Sprague Dawley rats 2017 Forkuo, A.D.; Ansah, C.; Pearson, D.; Gertsch, W.; Cirello, A.; Amaral, A.; Spear, J.; Wright, Colin W.; Rynn, C.
In vitro anti-malarial interaction and gametocytocidal activity of cryptolepine 2017 Forkuo, A.D.; Ansah, C.; Mensah, K.B.; Annan, K.; Gyan, B.; Theron, A.; Mancama, D.; Wright, Colin W.
Identification of compounds with cytotoxic activity from the leaf of the Nigerian medicinal plant, Anacardium occidentale L. (Anacardiaceae) 2017 Taiwo, Bamigboye J.; Fatokun, Amos A.; Olubiyi, O.O.; Bamigboye-Taiwo, O.T.; van Heerden, F.R.; Wright, Colin W.
Synthesis and biological evaluation of N-cyanoalkyl-, Naminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents 2016 Sola, I.; Artigas, A.; Taylor, M.C.; Perez-Areales, F.J.; Viayna, E.; Clos, M.V.; Perez, B.; Wright, Colin W.; Kelly, J.M.; Muñoz-Torrero, D.
Traditional remedies: an ally in the fight against infectious diseases? 2012 Wright, Colin W.
Recent developments in research on terrestrial plants used for the treatment of malaria. 2010 Wright, Colin W.
Antileishmanial activity of cryptolepine analogues and apoptotic effects of 2,7-dibromocryptolepine against Leishmania donovani promastigotes. 2012 Hazra, S.; Ghosh, S.; Debnath, S.; Seville, Scott; Prajapati, V.K.; Wright, Colin W.; Sundar, S.; Hazra, B.
Metabolism of cryptolepine and 2-fluorocryptolepine by aldehyde oxidase 2012 Stell, J. Godfrey P.; Wheelhouse, Richard T.; Wright, Colin W.
Complete NMR assignments of tubulosine 2012 Kantamreddi, Venkata Siva Satya Narayana; Wright, Colin W.
Effects of the antimalarial compound cryptolepine and its analogues in human lymphocytes and sperm in the Comet assay 2011 Gopalan, Rajendran C.; Emerce, E.; Wright, Colin W.; Karahalil, B.; Karakaya, A.E.; Anderson, Diana
Low Temperature X-Ray Crystallographic Structure of the Antiplasmodial Compound 5-N-Hydroxyethanequindoline Hydrochloride 0.5CH3OH. 2011 Hampson, Hannah C.; Ho, Chung Y.; Palmer, R.A.; Potter, B.S.; Helliwell, M.; Wright, Colin W.
Whole plant extracts versus single compounds for the treatment of malaria: synergy and positive interactions. 2011 Rasoanaivo, P.; Wright, Colin W.; Willcox, M.L.; Gilbert, B.
Cryptolepine-Induced Cell Death of Leishmania donovani Promastigotes Is Augmented by Inhibition of Autophagy. 2011 Sengupta, S.; Chowdhury, S.; BoseDasgupta, S.; Wright, Colin W.; Majumder, H.K.
A new embelin from the mangrove Aegiceras corniculatum. 2015 Thota, S.P.R.; Sarma, N.S.; Murthy, Y.L.N.; Kantamreddi, Venkata Siva Satya Narayana; Wright, Colin W.
Anticandida Agents from a Tanzanian Plant Albizia anthelmintica. 2015 Runyoro, D.K.B.; Joseph, C.C.; Ngassapa, O.D.; Darokar, M.P.; Srivastava, S.K.; Matee, M.I.N.; Wright, Colin W.
Huprines as a new family of dual acting trypanocidal–antiplasmodial agents 2011 Defaux, J.; Sala, M.; Formosa, X.; Galdeano, C.; Taylor, M.C.; Kelly, J.M.; Wright, Colin W.; Camps, P.; Muñoz-Torrero, D.; Alobaid, Waleed A.A.
Synthesis, biological profiling and mechanistic studies of 4-aminoquinoline-based heterodimeric compounds with dual trypanocidal–antiplasmodial activity. 2015 Sola, I.; Castellà, S.; Viayna, E.; Galdeano, C.; Taylor, M.C.; Gbedema, Stephen Y.; Pérez, B.; Clos, M.V.; Jones, D.C.; Fairlamb, A.H.; Wright, Colin W.; Kelly, J.M.; Muñoz-Torrero, D.
Prenylated flavanone derivatives isolated from Erythrina addisoniae are potent inducers of apoptotic cell death 2015 Passreiter, C.M.; Suckow-Schnitker, A-K.; Kulawik, A.; Addae-Kyereme, Jonathan A.; Wright, Colin W.; Wätjen, W.
Clerodane diterpenes from Polyalthia longifolia (Sonn) Thw. var. pendula: Potential antimalarial agents for drug resistant Plasmodium falciparum infection. 2015 Gbedema, Stephen Y.; Bayor, M.T.; Annan, K.; Wright, Colin W.
Synthesis and antiprotozoal activity of oligomethylene- and p-phenylene-bis(methylene)-linked bis(+)-huprines. 2014 Sola, I.; Artigas, A.; Taylor, M.C.; Gbedema, Stephen Y.; Perez, B.; Clos, M.V.; Wright, Colin W.; Kelly, J.M.; Muñoz-Torrero, D.
Inhibition of Neuroinflammation in LPS-Activated Microglia by Cryptolepine. 2013 Olajide, O.A.; Bhatia, H.S.; de Oliveira, A.C.P.; Wright, Colin W.; Fiebich, B.L. Olajide, O.A., Bhatia, H., A.C., de Oliveira, A.C.P., Wright, C.W. and Fiebich, B.L. (2013) Inhibition of neuroinflammation in LPS-activated microglia by cryptolepine. Evidence-Based Complementary and Alternative Medicine, Article ID 459723.
Cajachalcone: An Antimalarial Compound from Cajanus cajan Leaf Extract 2013 Ajaiyeoba, E.O.; Ogbole, O.O.; Abiodun, O.O.; Ashidi, J.S.; Houghton, P.J.; Wright, Colin W.
Anti-neuroinflammatory properties of synthetic cryptolepine in human neuroblastoma cells: Possible involvement of NF-κB and p38 MAPK inhibition. 2013 Olajide, O.A.; Bhatia, H.S.; de Oliveira, A.C.P.; Wright, Colin W.; Fiebich, B.L.
Screening Indian plant species for antiplasmodial properties – ethnopharmacological compared to random selection. 2012 Kantamreddi, Venkata Siva Satya Narayana; Wright, Colin W.
Genomewide expression profiling of the cryptolepine-induced toxicity in Saccharomyces cerevisiae. 2008 Rojas, M.; Wright, Colin W.; Pina, B.; Portugal, J.
A cytotoxic diterpenoid from Croton membranaceus, the major constituent of anticancer herbal formulations in Ghana 2008 Bayor, M.T.; Ayim, J.S.K.; Marston, G.; Phillips, Roger M.; Shnyder, Steven D.; Wheelhouse, Richard T.; Wright, Colin W.
X-ray crystallographic structure of the potent antiplasmodial compound 2,7-dibromocryptolepine acetic acid solvate. 2008 Potter, B.S.; Lisgarten, J.N.; Pitts, J.E.; Palmer, R.A.; Wright, Colin W.
Structure of the antiplasmodial compound 7,9-dinitrocryptolepine hydrochloride methanol solvate. 2008 Lisgarten, J.N.; Potter, B.S.; Pitts, J.E.; Palmer, R.A.; Wright, Colin W.
Antiplasmodial compounds from Cassia siamea stem bark extract. 2008 Ajaiyeoba, E.O.; Ashidi, J.S.; Okpako, Larry Commander; Houghton, P.J.; Wright, Colin W.
New polyhydroxy sterols from the marine sponge Callyspongia fibrosa (Ridley and Dendly). 2010 Rao, T.S.P.; Sarma, N.S.; Murthy, Y.L.N.; Kantamreddi, Venkata Siva Satya Narayana; Wright, Colin W.; Parameswaran, P.S.
Ancient Chinese methods are remarkably effective for the preparation of artemisinin-rich extracts of Qing Hao with potent antimalarial activity. 2010 Wright, Colin W.; Linley, Peter A.; Brun, R.; Wittlin, S.; Hsu, E.
Screening of Tanzanian medicinal plants against Plasmodium falciparum and human immunodeficiency virus. 2010 Maregesi, S.; Van Miert, S.; Pannecouque, C.; Feiz-Haddad, M.H.; Hermans, N.; Wright, Colin W.; Vlietinck, A. J.; Aspers, S.; Pieters, L.
Phytotherapy used in Orissa State India, for treating malaria. 2009 Kantamreddi, Venkata Siva Satya Narayana; Parida, S.; Kommula, S.M.; Wright, Colin W.
Anti-inflammatory properties of cryptolepine. 2010 Olajide, O.A.; Ajayi, A.A.; Wright, Colin W.
Evaluation of cryptolepine and huperzine derivatives as lead compounds towards new agents for the treatment of human African Trypanosomiasis. 2009 Oluwafemi, A.J.; Okanla, O.; Camps, P.; Muñoz-Torrero, D.; Mackey, Z.B.; Chiang, P.K.; Seville, Scott; Wright, Colin W.
Characterization of the cytotoxic activity of the indoloquinoline alkaloid cryptolepine in human tumour cell lines and primary cultures of tumour cells from patients. 2009 Laryea, D.; Isaksson, A.; Wright, Colin W.; Larsson, R.; Nygren, P.
Prenylated flavonoid derivatives from the bark of Erythrina addisoniae. 2008 Watjen, W.; Suckow-Schnitker, A-K.; Rohrig, R.; Kulawik, A.; Addae-Kyereme, Jonathan A.; Wright, Colin W.; Passreiter, C.M.
Enhancement of the antiplasmodial activity of quassin by transformation into a gamma-lactone. 2003 Wright, Colin W.; Kirby, G.C; Phillipson, J.D; Warhurst, D.C.; Lang'at-Thoruwa, C.; Watt, R.A.
Synthesis of some cryptolepine analogues, assessment of their antimalarial and cytotoxic activities, and consideration of their antimalarial mode of action. 2005 Wright, Colin W.; Onyeibor, O.; Phillips, Roger M.; Shnyder, Steven D.; Croft, S.L.; Dodson, Hilary I.
Synthesis and evaluation of cryptolepine analogues for their potential as new antimalarial agents. 2001 Wright, Colin W.; Addae-Kyereme, Jonathan A.; Breen, Anthony G.; Brown, John E.; Cox, Marlene F.; Croft, S.L.; Gokcek, Yaman; Kendrick, H.; Phillips, Roger M.; Pollet, Pamela L.