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Dr. Chris Sutton

Associate Professor

Area
School of Chemistry & Biosciences
Faculty of Life Sciences
E-mail
C.W.Sutton@bradford.ac.uk
Phone
+441274236480
Dr. Chris Sutton
12 publications

Biography

Chris Sutton obtained his B.Sc. degree and Ph.D. in Biochemistry from University of Liverpool, with combined studies in the Department of Plant Molecular Biology, University of California, Berkeley. He was then a Postdoctoral Research Scientist at the London School of Hygiene and Tropical Medicine, investigating the mechanisms of pathogenicity of Vibrio cholerae. He joined the premier of UK biotechnology company, Celltech Limited, as a Senior Scientist in Protein Biochemistry purifying novel proteins of therapeutic interest, and was later promoted to Group Leader of Analytical Biochemistry. With the emergence of mass spectrometry for protein characterisation, he moved to ThermoFinnigan and developed novel applications for matrix assisted laser desorption mass spectrometry (MALDI MS) including pioneering work in proteomics. He joined Kratos Analytical as MALDI MS Product Manager and was responsible for the marketing and promotion, including co-ordinating the research activity of a worldwide group of 25 application specialists who were developing MALDI MS solutions for the future. He was subsequently promoted to Business Manager for the product lines with a staff of 50, doubling revenues during this time to 10 million USD per annum. Since August 2005, Chris has joined the Institute of Cancer Therapeutics in the University of Bradford as Senior Lecturer in Proteomics Chemistry and Mass Spectrometry. With the support of Yorkshire Cancer Research, he has develop three key areas of research (1) identification of new proteins as candidate diagnostic biomarkers, (2) identification of proteins affected by the action of anticancer drugs and (3) identification of new target proteins for anticancer drug development. He has developed collaborations with academic groups in Hull, York, Sheffield and Leeds within the UK and Toronto, Cyprus, Pakistan internationally.  

Research

Proteomics and mass spectrometry.  Current Projects.

  • Identification of biomarkers for the early detection of breast cancer 
  • Characterisation of drug resistance mechanisms in colorectal and breast cancer
  • Proteomic stratification of head and neck cancers
  • Profiling cytochrome P450s isoforms in cancer tissues and cell lines
  • Influence of microenvironmental changes on cancer cell phenotype
  • investigation and characterisation of close proximity derived liquid biopsies/biofluids


Professional activities

  • Liverpool - PhD
  • Liverpool - BSc (Hons)

  • University of Bradford, Bradford, West Yorkshire - Senior Lecturer in Proteomics and Mass Spectrometry (1 January 2005)
  • Oxford Instruments, Abingdon, Oxon - Proteomics and Mass Spectrometry Consultant (1 January 2005)
  • Shimadzu Corporation, Trafford, Manchester - Mass Spectrometry Business Manager (1 January 2001)
  • Shimadzu Corporation, Trafford, Manchester - Mass Spectrometry Product Manager (1 January 1998)
  • Thermo Scientific, Hemel Hempstead, Herts. - Product Manager (1 January 1996)
  • Thermo Scientific, Hemel Hempstead, Herts. - Senior Research Biochemist (1 January 1991)
  • Celltech Limited, Slough, Berks. - Group Leader of Analytical Biochemistry (1 January 1989)
  • Celltech Limited, Slough, Berks. - Senior Research Scientist (1 January 1985)
  • London School of Hygiene and Tropical Medicine, London - Wellcome Foundation Postdoctoral Research Scientist (1 January 1982)

  • Director: A Director of the British Society of Proteomics Research

Publications