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Dr. Arathyram Ramachandra Kurup Sasikala

Information about Dr. Arathyram Ramachandra Kurup Sasikala at the University of Bradford.


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Photo of Dr. Arathyram Ramachandra Kurup Sasikala

Biography

Dr. Arathyram Ramachandra Kurup Sasikala is an Assistant Professor at the Centre for Pharmaceutical Engineering Science and Institute of Cancer Therapeutics at the Faculty of Life Sciences. Her vision is to develop next-generation nanotherapeutics for human diseases with unmet clinical needs through non-invasive approaches. She is an interdisciplinary biomaterial scientist who completed her master’s degree in Physics and continued her journey toward nanomedicine research and worked on the interface between materials science and biology. After receiving her doctorate from the Department of Bionanosystem Engineering, Jeonbuk National University (JBNU) South Korea, she was quickly recognised for her work with a three-year Young Investigator Award from the National Research Foundation of Korea. Meanwhile, she's taken a position as an Assistant Research Professor at the JBNU. Her role as an independent PI allowed her to serve as Primary Supervisor for two master's theses and as Co-supervisor for one doctoral thesis. To further develop her career as an independent research leader in next-generation biomaterials, she moved to the University of Birmingham as a Marie Curie Fellow, where she investigated a new strategy for the non-invasive modulation of the Blood-Brain Barrier to overcome the unmet need for delivering drugs to the brain. Arathyram is passionate about communicating her research to the public and patients through PPI meetings and various outreach activities like European Researchers Night, Nottingham Soapbox Science, Pint of Science etc. She is the Outreach, Collaborations, and Dissemination Lead of the Centre for Pharmaceutical Engineering Science.

Research

I have a strong interest in the development and translation of next-generation nanotherapeutics to address breakthrough healthcare challenges. I have always tried to broaden my horizons through interdisciplinary research and partnerships since receiving my Ph.D. and throughout my academic career. Our group is focused on developing innovative ways for producing smart and hybrid organic-inorganic nanomaterials with desirable properties to be used as targeted drug delivery carriers, non-invasive anticancer agents, tissue regeneration matrices, and bioimaging platforms. In our research, we use a highly interdisciplinary approach and work at the intersection of materials science, engineering, and biology. Some ongoing research areas include:1. Synthesis of multifunctional nanomaterials for cancer theranostics ApplicationMagnetic hyperthermiaMagnetic Resonance ImagingPhotothermal therapy Photodynamic therapy Second Harmonic Generation Imaging2. Development of non-invasive Blood Brain Barrier modulators for targeted drug delivery to the brainNanoelectroporation PiezoMagnetic nanoparticles Carbon nanoneedles3. Remotely controlled stimuli-responsive Drug Delivery systemsPH sensitive Ultrasound sensitive Magnetic field sensitiveLight Sensitive 4. Development of Implantable Anticancer Devices (IADs) Electrospun nanofiber-based IADs Hydrogels based IADsMicroneedle based IADs 5. Biomimetic nanomaterials for regenerative medicine ApplicationPiezoelectric whitlockite nanoparticles Piezoelectric Nerve conduits Piezoelectric Bone implants Piezoelectric Wound dressing patches

Professional activities

Information about education, employment and areas of particular interest for Dr. Arathyram Ramachandra Kurup Sasikala is as follows: