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Professor Anant Paradkar,
Professor of Pharmaceutical Engineering

Information about Professor Anant Paradkar at the University of Bradford.

School of Pharmacy & Medical Sciences
(Faculty of Life Sciences)
Email:
a.paradkar1@bradford.ac.uk
Telephone:
+44 1274 233900
Photo of Professor Anant Paradkar

Biography

Professor Anant Paradkar holds an Interdisciplinary Chair in Pharmaceutical Engineering Science and is Director of the Centre for Pharmaceutical Engineering Science. He completed his PhD in Pharmaceutics and joined Bradford following a 20 year academic career in India. He has worked on various interdisciplinary collaborative research projects in the areas of process development and crystal and particle engineering, developing techniques such as crystallo-co-agglomeration, melt granulation, sono-crystallisation, spray drying of low Tg materials and liquid crystal precursors. He is currently working on the application of hot melt extrusion and sono-crystallisation to generate co-crystals and has been awarded a EPSRC funding and Yorkshire Enterprise Fellowship to strengthen exploitation and impact of this work.In India, he received research funding from the All India Council for Technical Education, University Grants Commission, Department of Science and Technology and the Ministry of Defence. He has received an India-JSPS International Joint project on liquid crystalline systems, UK-India Education and Research Initiative (UKIERI) Fellowship and a Royal Society UK-India Science Network award He has supervised 10 PhD and 45 MPharm candidates and published over 90 research papers. Currently, he is supervising/ co-supervising 15 PhD students in various areas of research.Awards and Recognition: 2010: Business Innovation Award, University of Bradford 2010: Finalist, Yorkshire Forward Innovator10 Award 2009: Yorkshire Enterprise Fellowship 2009: Research and Knowledge Transfer Showcase Award for interdisciplinary research presentation2007: UK India Education and Research Initiative (UKIERI) Fellowship 2006: Bharati Vidyapeeth Best Employee of the University2005: Indo-UK Science Network Scheme (Royal Society and DST, India) 2005: India-JSPS funded India-Japan Cooperation Programme (IJCP) 2005: Young Pharmacy Teacher Award by Association of Pharmaceutical Teachers of India (APTI)Professor Anant Paradkar holds an Interdisciplinary Chair in Pharmaceutical Engineering Science and is Director of the Centre for Pharmaceutical Engineering Science. He completed his PhD in Pharmaceutics and joined Bradford following a 20 year academic career in India. He has worked on various interdisciplinary collaborative research projects in the areas of process development and crystal and particle engineering, developing techniques such as crystallo-co-agglomeration, melt granulation, sono-crystallisation, spray drying of low Tg materials and liquid crystal precursors. He is currently working on the application of hot melt extrusion and sono-crystallisation to generate co-crystals and has been awarded a EPSRC funding and Yorkshire Enterprise Fellowship to strengthen exploitation and impact of this work.In India, he received research funding from the All India Council for Technical Education, University Grants Commission, Department of Science and Technology and the Ministry of Defence. He has received an India-JSPS International Joint project on liquid crystalline systems, UK-India Education and Research Initiative (UKIERI) Fellowship and a Royal Society UK-India Science Network award He has supervised 10 PhD and 45 MPharm candidates and published over 90 research papers. Currently, he is supervising/ co-supervising 15 PhD students in various areas of research.Awards and Recognition: 2010: Business Innovation Award, University of Bradford 2010: Finalist, Yorkshire Forward Innovator10 Award 2009: Yorkshire Enterprise Fellowship 2009: Research and Knowledge Transfer Showcase Award for interdisciplinary research presentation2007: UK India Education and Research Initiative (UKIERI) Fellowship 2006: Bharati Vidyapeeth Best Employee of the University2005: Indo-UK Science Network Scheme (Royal Society and DST, India) 2005: India-JSPS funded India-Japan Cooperation Programme (IJCP) 2005: Young Pharmacy Teacher Award by Association of Pharmaceutical Teachers of India (APTI)

Research

Process Development: Currently my research focus is on non-infringing processing technologies for pharmaceuticals with special emphasis on Hot Melt Extrusion ( HME) and Ultrasound Assisted processing. Our interdisciplinary team has developed application of HME for co-crystallization. This solvent free continuous technology offers many advantages and easy for scale-up and commercialization. In process development we also focus on process optimization and characterization of process related properties like extensional rheology.In this area our group has linkages with Professor Guos group at Sichuan University, China and Dr. Kumarswamy and Dr. Suresh Bhat at National Chemical Laboratory, India. Technology Opportunity Solvent-Free Continuous Technology for Co-crystallizationFormulation Development: In the area of formulation development my focus is poorly soluble drug and nutraceutical molecules. Development of amorphous systems and liquid crystalline systems are adopted for different purposes.The novel drug delivery concepts are also extended to molecules from natural products. We are developing nanoparticulate delivery systems for treatment of neurodegenerative conditions, cancers and endometriosis. METRCProcess Analytical Technology: The interdisciplinary group provides us with strong engineering expertise required for process analytics. Application of in-line measurement systems are being used to understand the mechanisms of novel products developed and process optimization.Solid State Pharmaceutics:Crystal and Particle Engineering: Green technologies for particle engineering including Extrusion, ultrasound and microwavesAmorphous State Pharmaceuticals: Hot Melt Extrusion, Spray Drying especially low Tg drugs and stabilization using amphiphilic lipidsMolecular Pharmaceutics:Rheological basis for process and formulation performanceMolecular aspects in biopharmaceutical performance of targeted systemsMolecular basis for stabilized amorphous systemsRole of extensional rheology in melt extrusionNovel Drug Delivery Systems:Polymeric controlled release systems. Major focus on transdermal drug delivery systemMicroneedle and Magnetic Microarray Technologies for transdermal drug deliveryLiquid crystalline phases and their solid state precursorsInhaled drug delivery systemsMoulded tablets, Porous polymer matricesNanoparticulate delivery systemsPhytopharmaceuticals and Nutraceuticals:Applications of modern principles in design of extraction processes and delivery systems for phytochemicals and nutraceuticalsQbD and Process Analytical Technology (PAT):In –line rheology, spectroscopy (NIR, Raman) and ultrasound transmissionAdvanced statistical techniques: DoE, modelling, response surface methodsComputational and Predictive Pharmaceutics: ANN, Neurofuzzy logic, Mesoscale simulationsProcess Development: Currently my research focus is on non-infringing processing technologies for pharmaceuticals with special emphasis on Hot Melt Extrusion ( HME) and Ultrasound Assisted processing. Our interdisciplinary team has developed application of HME for co-crystallization. This solvent free continuous technology offers many advantages and easy for scale-up and commercialization. In process development we also focus on process optimization and characterization of process related properties like extensional rheology.In this area our group has linkages with Professor Guos group at Sichuan University, China and Dr. Kumarswamy and Dr. Suresh Bhat at National Chemical Laboratory, India. Technology Opportunity Solvent-Free Continuous Technology for Co-crystallizationFormulation Development: In the area of formulation development my focus is poorly soluble drug and nutraceutical molecules. Development of amorphous systems and liquid crystalline systems are adopted for different purposes.The novel drug delivery concepts are also extended to molecules from natural products. We are developing nanoparticCurrent ProjectsA Novel Continuous Method for Co-crystal Formation, EPSRC (EP/J003360/1)Development of Propolis Products, Technology Strategy Board KTP SchemeNanoparticulate Curcumin System with enhancers from Traditional Chinese Medicine (TCM) for treatment of Alzheimers, Changzhou People’s Hospital

Publications

There are 101 publications involving or that are attributed to Professor Anant Paradkar. They are listed as:

  • book chapter (4)
  • peer reviewed journal (97)

Book Chapter

Professor Anant Paradkar has 4 publication(s) listed under book chapter.
Title Year Publication name Journal Volume Pages Authors Editors ISSN Publisher DOI Location
Impact of the Polymorphic Form of Drugs/NCEs on Preformulation and Formulation Development 2019 Innovative Dosage Forms: Design and Development at Early Stage Innovative Dosage Forms: Design and Development at Early Stage MHD Bashir Alsirawan, Anant Paradkar Yogeshwar Bachhav Wiley‐VCH https://doi.org/10.1002/9783527812172.ch1
Aerosols in pharmaceutical product development 2019 Drug Delivery Systems Drug Delivery Systems 521 - 577 Deb P.K.;Abed S.N.;Maher H.;Al-Aboudi A.;Paradkar A.;Bandopadhyay S.;Tekade R.K. 9780128144879 10.1016/B978-0-12-814487-9.00011-9
Pharmaceutical and biomedical applications of polymers 2018 Basic Fundamentals of Drug Delivery Basic Fundamentals of Drug Delivery 203 - 267 Deb P.K.;Kokaz S.F.;Abed S.N.;Paradkar A.;Tekade R.K. 9780128179109 10.1016/B978-0-12-817909-3.00006-6
Protein/peptide drug delivery systems: Practical considerations in pharmaceutical product development 2018 Basic Fundamentals of Drug Delivery Basic Fundamentals of Drug Delivery 651 - 684 Deb P.K.;Al-Attraqchi O.;Chandrasekaran B.;Paradkar A.;Tekade R.K. 9780128179109 10.1016/B978-0-12-817909-3.00016-9

Peer Reviewed Journal

Professor Anant Paradkar has 97 publication(s) listed under peer reviewed journal.
Title Year Publication name Journal Volume Pages Authors Editors ISSN Publisher DOI Location
Design and evaluation of celecoxib porous particles using melt sonocrystallization. 2006 Paradkar, Anant R.; Maheshwari, M.; Kamble, R.; Grimsey, Ian M.; York, Peter
ApoE3 mediated poly(butyl) cyanoacrylate nanoparticles containing curcumin: study of enhanced activity of curcumin against beta amyloid induced cytotoxicity using in vitro cell culture model 2010 Mulik, R.S.; Monkkonen, J.; Juvonen, R.O.; Mahadik, K.R.; Paradkar, Anant R.
Shear and extensional rheology of hydroxypropyl cellulose melt using capillary rheometry 2009 Paradkar, Anant R.; Kelly, Adrian L.; Coates, Philip D.; York, Peter
Microstructural elucidation of self-emulsifying system: effect of chemical structure 2012 Patil, S.S.; Venugopal, E.; Bhat, S.; Mahadik, K.R.; Paradkar, Anant R.
Probing influence of mesophasic transformation on performance of self-emulsifying system: effect of ion 2012 Patil, S.S.; Venugopal, E.; Bhat, S.; Mahadik, K.R.; Paradkar, Anant R.
Monitoring ibuprofen-nicotinamide cocrystal formation during solvent free continuous cocrystallization (SFCC) using near infrared spectroscopy as a PAT tool 2012 Kelly, Adrian L.; Gough, Timothy D.; Dhumal, Ravindra S.; Halsey, S.A.; Paradkar, Anant R.
Polymorphic transformation of artemisinin by high temperature extrusion 2013 Kulkarni, Chaitrali S.; Kendrick, John; Kelly, Adrian L.; Gough, Timothy D.; Dash, Radha C.; Paradkar, Anant R.
Cocrystalization and simultaneous agglomeration using hot melt extrusion 2010 Dhumal, Ravindra S.; Kelly, Adrian L.; York, Peter; Coates, Philip D.; Paradkar, Anant R.
Stoichiometric control of co-crystal formation by solvent free continuous co-crystallization (SFCC). 2015 Kulkarni, Chaitrali S.; Wood, Clive; Kelly, Adrian L.; Gough, Timothy D.; Blagden, Nicholas; Paradkar, Anant R.
Investigation of Plasma Treatment on Micro-Injection Moulded Microneedle for Drug Delivery 2015 Nair, Karthik Jayan; Whiteside, Benjamin R.; Grant, Colin A.; Patel, Rajnikant; Tuinea-Bobe, Cristina-Luminita; Norris, Keith; Paradkar, Anant R.
Controlled release floating multiparticulates of metoprolol succinate by hot melt extrusion 2015 Malode, V.N.; Paradkar, Anant R.; Devarajan, P.V.
Development of selective DprE1 inhibitors: Design, synthesis, crystal structure and antitubercular activity of benzothiazolylpyrimidine-5-carboxamides 2015 Chikhale, R.; Menghani, S.; Babu, R.; Bansode, Ratnadeep V.; Bhargavi, G.; Karodia, Nazira; Rajasekharan, M.V.; Paradkar, Anant R.; Khedekar, Pramod
A novel transflectance near infrared spectroscopy technique for monitoring hot melt extrusion 2015 Kelly, Adrian L.; Halsey, S.A.; Bottom, R.A.; Korde, Sachin A.; Gough, Timothy D.; Paradkar, Anant R.
Coformer Replacement as an Indicator for Thermodynamic Instability of Cocrystals: Competitive Transformation of Caffeine:Dicarboxylic Acid 2016 Alsirawan, M.H.D. Bashir; Vangala, Venu R.; Kendrick, John; Leusen, Frank J.J.; Paradkar, Anant R. Alsirawan MHD B, Vangala VR, Kendrick J, Leusen FJJ and Paradkar A (2016) Coformer Replacement as an Indicator for Thermodynamic Instability of Cocrystals: Competitive Transformation of Caffeine:Dicarboxylic Acid. Crystal growth & design. Online before print, May 2016. DOI http://dx.doi.org/10.1021/acs.cgd.6b00458
Effect of Ultrasound on Molecular Structure Development of Polylactide 2014 Bao, W.; Wu, H.; Guo, S.; Paradkar, Anant R.; Kelly, Adrian L.; Brown, Elaine C.; Coates, Philip D.
Design, synthesis and pharmacological evaluation of pyrimidobenzothiazole-3-carboxylate derivatives as selective L-type calcium channel blockers 2016 Chikhale, R.; Thorat, S.; Pant, A.; Jadhav, A.; Thatipamula, K.C.; Bansode, Ratnadeep V.; Bhargavi, G.; Karodia, Nazira; Rajasekharan, M.V.; Paradkar, Anant R.; Khedekar, Pramod
Tracing the architecture of caffeic acid phenethyl ester cocrystals: studies on crystal structure, solubility, and bioavailability implications 2016 Ketkar, S.S.; Pagire, Sudhir K.; Goud, N.R.; Mahadik, K.R.; Nangia, A.; Paradkar, Anant R.
Systematic identification of thermal degradation products of HPMCP during hot melt extrusion process 2015 Karandikar, Hrushikesh M.; Ambardekar, Rohan; Kelly, Adrian L.; Gough, Timothy D.; Paradkar, Anant R.
Synthesis of caffeine/maleic acid co-crystal by ultrasound assisted slurry co-crystallization 2017 Journal of Pharmaceutical Sciences 106 Apshingekar, Prafulla P.; Aher, Suyog; Kelly, Adrian L.; Brown, Elaine C.; Paradkar, Anant R. https://doi.org/10.1016/j.xphs.2016.09.009
Near infra red spectroscopy as a multivariate process analytical tool for predicting pharmaceutical co-crystal concentration 2016 Wood, Clive; Alwati, Abdolati; Halsey, S.A.; Gough, Timothy D.; Brown, Elaine C.; Kelly, Adrian L.; Paradkar, Anant R.
Spherical Crystallization of Carbamazepine/Saccharin Co-Crystals: Selective Agglomeration and Purification through Surface Interactions 2013 Pagire, Sudhir K.; Korde, Sachin A.; Whiteside, Benjamin R.; Kendrick, John; Paradkar, Anant R.
Mechanism for Polymorphic Transformation of Artemisinin during High Temperature Extrusion 2013 Kulkarni, Chaitrali S.; Kelly, Adrian L.; Kendrick, John; Gough, Timothy D.; Paradkar, Anant R.
Can green synthesized propolis loaded silver nanoparticulate gel enhance wound healing caused by burns? 2015 Patil, S.S.; Desai, N.; Mahadik, K.R.; Paradkar, Anant R.
Exploring Microstructural Changes in Structural Analogues of Ibuprofen-Hosted In Situ Gelling System and Its Influence on Pharmaceutical Performance 2015 Patil, S.S.; Venugopal, E.; Bhat, S.; Mahadik, K.R.; Paradkar, Anant R.
Effect of cocrystallization techniques on compressional properties of caffeine/oxalic acid 2:1 cocrystal 2013 Aher, Suyog; Dhumal, Ravindra S.; Mahadik, K.R.; Ketolainen, J.; Paradkar, Anant R.
A quality by design approach using artificial intelligence techniques to control the critical quality attributes of ramipril tablets manufactured by wet granulation 2013 Aksu, B.; Paradkar, Anant R.; de Matas, Marcel; Özer, Ö.; Güneri, T.; York, Peter
Yeast consortium isolated from Woodfordia fruticosa flowers proved to be instrumental for traditional Ayurvedic fermentation 2013 Bhondave, P.; Burase, R.; Takale, S.; Paradkar, Anant R.; Patil, S.; Mahadik, K.R.; Harsulkar, A.
Extrusion-Spheronization of Talc using Microcrystalline Cellulose as a Pellet Aid: Part I 2014 Jadhav, N.; Gade, M.; Salunkhe, N.; Paradkar, Anant R.
Alleviating exercise-induced muscular stress using neat and processed bee pollen: oxidative markers, mitochondrial enzymes, and myostatin expression in rats 2015 Ketkar, S.S.; Rathore, A.S.; Kandhare, A.; Lohidasan, S.; Bodhankar, S.; Paradkar, Anant R.; Mahadik, K.R.
Investigation of the nutraceutical potential of monofloral Indian mustard bee pollen 2014 Ketkar, S.S.; Rathore, A.S.; Lohidasan, S.; Rao, L.; Paradkar, Anant R.; Mahadik, K.R.
A comparative study of the effect of spray drying and hot-melt extrusion on the properties of amorphous solid dispersions containing felodipine 2014 Mahmah, O.; Tabbakh, R.; Kelly, Adrian L.; Paradkar, Anant R.
Mechanism of hydrogen-bonded complex formation between ibuprofen and nanocrystalline hydroxyapatite 2017 Ryabenkova, Yulia; Jadav, Niten B.; Conte, M.; Hippler, M.F.A.; Reeves-McLaren, N.; Coates, Philip D.; Twigg, Peter C.; Paradkar, Anant R.
Application of hot melt extrusion for improving bioavailability of artemisinin a thermolabile drug 2017 Kulkarni, Chaitrali S.; Kelly, Adrian L.; Gough, Timothy D.; Jadhav, V.; Singh, K.; Paradkar, Anant R.
Thermodynamic investigation of carbamazepine-saccharin co-crystal polymorphs 2017 Pagire, Sudhir K.; Jadav, Niten B.; Vangala, Venu R.; Whiteside, Benjamin R.; Paradkar, Anant R.
Continuous Manufacturing of Cocrystals Using Solid State Shear Milling Technology 2018 Korde, Sachin A.; Pagire, Sudhir K.; Pan, H.; Seaton, Colin C.; Kelly, Adrian L.; Chen, Y.; Wang, Q.; Coates, Philip D.; Paradkar, Anant R.
In-process rheometry as a PAT tool for hot melt extrusion 2018 Kelly, Adrian L.; Gough, Timothy D.; Isreb, Mohammad; Dhumal, Ravindra S.; Jones, J.W.; Nicholson, S.; Dennis, A.B.; Paradkar, Anant R.
Quality by design approach: Application of artificial intelligence techniques of tablets manufactured by direct compression 2012 AAPS PharmSciTech 13 1138 - 1146 Aksu B.;Paradkar A.;De Matas M.;Özer O.;Güneri T.;York P. 1530-9932 10.1208/s12249-012-9836-x
Transferrin mediated solid lipid nanoparticles containing curcumin: Enhanced in vitro anticancer activity by induction of apoptosis 2010 International Journal of Pharmaceutics 398 190 - 203 Mulik R.;Mönkkönen J.;Juvonen R.;Mahadik K.;Paradkar A. 0378-5173 10.1016/j.ijpharm.2010.07.021
Isolation, biochemical and genetic characterizations of alcohol-producing yeasts from the flowers of Woodfordia fruticosa 2013 Journal of Young Pharmacists 5 191 - 194 Manwar J.;Mahadik K.;Paradkar A.;Sathiyanarayanan L.;Vohra M.;Patil S. 0975-1483 10.1016/j.jyp.2013.11.007
Microwave assisted synthesis of caffeine/maleic acid co-crystals: The role of the dielectric and physicochemical properties of the solvent 2013 CrystEngComm 15 3705 - 3710 Pagire S.;Korde S.;Ambardekar R.;Deshmukh S.;Dash R.;Dhumal R.;Paradkar A. 1466-8033 10.1039/c3ce40292d
Adsorption studies of bromhexine hydrochloride on talc 2013 Research Journal of Pharmacy and Technology 6 1247 - 1250 Jadhav N.;Paradkar A.;Shah G. 0974-360X
Particle engineering using sonocrystallization: Salbutamol sulphate for pulmonary delivery 2009 International Journal of Pharmaceutics 368 129 - 137 Dhumal R.;Biradar S.;Paradkar A.;York P. 0378-5173 10.1016/j.ijpharm.2008.10.006
Development and validation of a densitometric HPTLC method for simultaneous analysis of wedelolactone and asiaticoside in a polyherbal formulation 2010 Acta Chromatographica 22 651 - 663 Sathiyanarayanan L.;Paradkar A.;Mahadik K. 1233-2356 10.1556/AChrom.22.2010.4.13
Study on mechanism for amorphous drug stabilization using Gelucire 50/13 2009 Chemical and Pharmaceutical Bulletin 57 937 - 942 Shimpi S.;Mahadik K.;Paradkar A. 0009-2363 10.1248/cpb.57.937
Effect of drug content and agglomerate size on tabletability and drug release characteristics of bromhexine hydrochloridetalc agglomerates prepared by crystallo-co-agglomeration 2010 Acta Pharmaceutica 60 25 - 38 Jadhav N.;Pawar A.;Paradkar A. 1330-0075 10.2478/v10007-010-0002-2
Characterization of Cashew nut gum as a binder in tablet formulation 2012 Journal of International Pharmaceutical Research 4 95 - 98 Wairkar S.;Ambike A.;Paradkar A. 0975-2366
Preparation of amorphous cefuroxime axetil nanoparticles by sonoprecipitation for enhancement of bioavailability 2008 European Journal of Pharmaceutics and Biopharmaceutics 70 109 - 115 Dhumal R.;Biradar S.;Yamamura S.;Paradkar A.;York P. 0939-6411 10.1016/j.ejpb.2008.04.001
Novel pepper extract for enhanced P-glycoprotein inhibition 2009 Journal of Pharmacy and Pharmacology 61 1179 - 1186 Aher S.;Biradar S.;Gopu C.;Paradkar A. 0022-3573 10.1211/jpp.61.09.0007
Cefuroxime axetil solid dispersion with polyglycolized glycerides for improved stability and bioavailability 2009 Journal of Pharmacy and Pharmacology 61 743 - 751 Dhumal R.;Biradar S.;Aher S.;Paradkar A. 0022-3573 10.1211/jpp.61.06.0006
Design, synthesis and pharmacological evaluation of pyrimidobenzothiazole-3-carboxylate derivatives as selective L-type calcium channel blockers 2015 Bioorganic and Medicinal Chemistry 23 6689 - 6713 Chikhale R.;Thorat S.;Pant A.;Jadhav A.;Thatipamula K.;Bansode R.;Bhargavi G.;Karodia N.;Rajasekharan M.;Paradkar A.;Khedekar P. 0968-0896 10.1016/j.bmc.2015.09.009
Evaluation of local drug-delivery system containing 2% whole turmeric gel used as an adjunct to scaling and root planing in chronic periodontitis: A clinical and microbiological study 2011 Journal of Indian Society of Periodontology 15 35 - 38 Behal R.;Mali A.;Gilda S.;Paradkar A. 0972-124X 10.4103/0972-124X.82264
Mapping ion-induced mesophasic transformation in lyotropic in situ gelling system and its correlation with pharmaceutical performance 2013 Pharmaceutical Research 30 1906 - 1914 Patil S.;Venugopal E.;Bhat S.;Mahadik K.;Paradkar A. 0724-8741 10.1007/s11095-013-1033-4
Rheological investigation of self-emulsification process: Effect of co-surfactant 2009 Journal of Pharmacy and Pharmaceutical Sciences 12 164 - 174 Biradar S.;Dhumal R.;Paradkar A. 1482-1826
Preparation and evaluation of talc agglomerates obtained by wet spherical agglomeration as a substrate for coating 2011 Pharmaceutical Development and Technology 16 152 - 161 Jadhav N.;Pawar A.;Paradkar A. 1083-7450 10.3109/10837450903544567
Design, synthesis, pharmacological evaluation and molecular docking studies of substituted oxadiazolyl-2-oxoindolinylidene propane hydrazide derivatives 2016 Journal of the Brazilian Chemical Society 27 1998 - 2010 Kerzare D.;Chikhale R.;Bansode R.;Amnerkar N.;Karodia N.;Paradkar A.;Khedekar P. 0103-5053 10.5935/0103-5053.20160090
Characterization of thermal and rheological properties of zidovidine, lamivudine and plasticizer blends with ethyl cellulose to assess their suitability for hot melt extrusion 2011 European Journal Of Pharmaceutical Sciences 44 471 - 478 Maru S.;De Matas M.;Kelly A.;Paradkar A. 0928-0987 10.1016/j.ejps.2011.09.003
Nootropic activity of lipid-based extract of Bacopa monniera Linn. compared with traditional preparation and extracts 2009 Journal of Pharmacy and Pharmacology 61 1537 - 1544 Lohidasan S.;Paradkar A.;Mahadik K. 0022-3573 10.1211/jpp/61.11.0014
Development of stability-enhanced ternary solid dispersions via combinations of HPMCP and Soluplus®processed by hot melt extrusion 2017 International Journal of Pharmaceutics 532 603 - 611 Albadarin A.;Potter C.;Davis M.;Iqbal J.;Korde S.;Pagire S.;Paradkar A.;Walker G. 0378-5173 10.1016/j.ijpharm.2017.09.035
Free radical scavenging and anti-inflammatory activity of Indian propolis 2009 Pharmacologyonline 3 991 - 1002 Ambardekar R.;Gilda S.;Mahadik K.;Harsulkar A.;Paradkar A. 1827-8620
Ultrasound-assisted preparation of novel ibuprofen-loaded excipient with improved compression and dissolution properties 2016 Drug Development and Industrial Pharmacy 42 1553 - 1563 Gandhi P.;Patil S.;Aher S.;Paradkar A. 0363-9045 10.3109/03639045.2016.1151035
Application of hot melt extrusion for improving bioavailability of artemisinin a thermolabile drug 2018 Drug Development and Industrial Pharmacy 44 206 - 214 Kulkarni C.;Kelly A.;Gough T.;Jadhav V.;Singh K.;Paradkar A. 0363-9045 10.1080/03639045.2017.1386200
Apoptosis-induced anticancer effect of transferrin-conjugated solid lipid nanoparticles of curcumin 2012 Cancer Nanotechnology 3 65 - 81 Mulik R.;Mönkkönen J.;Juvonen R.;Mahadik K.;Paradkar A. 1868-6958 10.1007/s12645-012-0031-2
Study of polymorphs of progesterone by novel melt sonocrystallization technique: A technical note 2010 AAPS PharmSciTech 11 1493 - 1498 Tripathi R.;Biradar S.;Mishra B.;Paradkar A. 1530-9932 10.1208/s12249-010-9508-7
Enhancement of hepatoprotective efficacy of propolis by fabrication of liposomes, as a platform nano-formulation for multi-component natural medicine 2012 Current Drug Delivery 9 477 - 486 Ambardekar R.;Mahadik K.;Paradkar A.;Harsulkar A. 1567-2018 10.2174/156720112802650653
Professor Peter York—A Distinguished Career in Powders, Processing, and Particle Design 2017 Journal of Pharmaceutical Sciences 106 2 - 4 Taylor L.;Rantanen J.;Paradkar A.;Kawashima Y.;Zhang J. 0022-3549 10.1016/j.xphs.2016.09.006
Liquid crystalline phase as a probe for crystal engineering of lactose: Carrier for pulmonary drug delivery 2015 European Journal Of Pharmaceutical Sciences 68 43 - 50 Patil S.;Mahadik K.;Paradkar A. 0928-0987 10.1016/j.ejps.2014.11.007
Ultrasound assisted cocrystallization from solution (USSC) containing a non-congruently soluble cocrystal component pair: Caffeine/maleic acid 2010 European Journal Of Pharmaceutical Sciences 41 597 - 602 Aher S.;Dhumal R.;Mahadik K.;Paradkar A.;York P. 0928-0987 10.1016/j.ejps.2010.08.012
ApoE3 mediated polymeric nanoparticles containing curcumin: Apoptosis induced in vitro anticancer activity against neuroblastoma cells 2012 International Journal of Pharmaceutics 437 29 - 41 Mulik R.;Mönkkönen J.;Juvonen R.;Mahadik K.;Paradkar A. 0378-5173 10.1016/j.ijpharm.2012.07.062
Enhanced brain targeting of curcumin by intranasal administration of a thermosensitive poloxamer hydrogel 2013 Journal of Pharmacy and Pharmacology 65 807 - 816 Chen X.;Zhi F.;Jia X.;Zhang X.;Ambardekar R.;Meng Z.;Paradkar A.;Hu Y.;Yang Y. 0022-3573 10.1111/jphp.12043
Development of curcuminoids loaded poly(butyl) cyanoacrylate nanoparticles: Physicochemical characterization and stability study 2009 European Journal Of Pharmaceutical Sciences 37 395 - 404 Mulik R.;Mahadik K.;Paradkar A. 0928-0987 10.1016/j.ejps.2009.03.009
Combined Virtual/Experimental Multicomponent Solid Forms Screening of Sildenafil: New Salts, Cocrystals and Hybrid Salt-Cocrystals 2018 CRYSTAL GROWTH & DESIGN (ONLINE) Rafael Barbas, Merce Font-Bardia, Anant Paradkar, Christopher A. Hunter, and Rafel Prohens ACS 10.1021/acs.cgd.8b01413
Novel nicotinamide skin-adhesive hot melt extrudates for treatment of acne 2018 EXPERT OPINION ON DRUG DELIVERY 15 Maha Nasr, Hrushikesh Karandikar, Rasha T.A. Abdel-Aziz, Noha Moftah, Anant Paradkar 1742-5247 Taylor and Francis 10.1080/17425247.2018.154628
Development and evaluation of nanoemulsion and microsuspension formulations of curcuminoids for lung delivery with a novel approach to understanding the aerosol performance of nanoparticles 2019 Al Ayoub, Yuosef; Gopalan, Rajendran C.; Najafzadeh, Mojgan; Mohammad, Mohammad A.; Anderson, Diana; Paradkar, Anant R.; Assi, Khaled H.
Novel nicotinamide skin-adhesive hot melt extrudates for treatment of acne 2018 Nasr, M.; Karandikar, H.; Abdel-Aziz, R.T.A.; Moftah, N.; Paradkar, Anant R.
Combined virtual/experimental multicomponent solid forms screening of sildenafil: new salts, cocrystals, and hybrid salt-cocrystals 2018 Barbas, R.; Font-Bardia, M.; Paradkar, Anant R.; Hunter, C.A.; Prohens, R.
Hot-melt extrusion process impact on polymer choice of glyburide solid dispersions: The effect of wettability and dissolution. 2019 International Journal of Pharmaceutics 559 Alshafiee M;Aljammal MK;Markl D;Ward A;Walton K;Blunt L;Korde S;Pagire SK;Kelly AL;Paradkar A;Conway BR;Asare-Addo K; 1873-3476 10.1016/j.ijpharm.2019.01.038
Polymorphs of Curcumin and Its Cocrystals With Cinnamic Acid 2019 Rathi, N.; Paradkar, Anant R.; Gaikar, V.G.
Gaps in Propolis Research: Challenges Posed to Commercialisation and the Need for an Holistic Approach 2019 Katekhaye, S.; Fearnley, H.; Fearnley, J.; Paradkar, Anant R.
Injection Moulded Controlled Release Amorphous Solid Dispersions: Synchronized Drug and Polymer Release for Robust Performance. 2020 International Journal of Pharmaceutics 575 Deshmukh S;Paradkar A;Abrahmsén-Alami S;Govender R;Viridén A;Winge F;Matic H;Booth J;Kelly A; 1873-3476 10.1016/j.ijpharm.2019.118908
Improving Stability of Effervescent Products by Co-Crystal Formation: A Novel Application of Crystal Engineered Citric Acid 2020 Crystal Growth and Design 20 4839 - 4844 Pagire, SK; Seaton, CC; Paradkar, A ACS https://doi.org/10.1021/acs.cgd.0c00616
Improving Stability of Effervescent Products by Co-Crystal Formation: A Novel Application of Crystal Engineered Citric Acid 2020 Crystal Growth and Design 20 4839 - 4844 Pagire, SK; Seaton, CC; Paradkar, A ACS https://doi.org/10.1021/acs.cgd.0c00616
Understanding Matrix Assisted Continuous Cocrystallisation using Data Mining approach in Quality by Design (QbD)* 2020 Crystal Growth and Design 20 Billy Chabalenge, Sachin Korde, Adrian L Kelly, Daniel Neagu and Anant Paradkar ACS https://doi.org/10.1021/acs.cgd.0c00338
Understanding Matrix Assisted Continuous Cocrystallisation using Data Mining approach in Quality by Design (QbD)* 2020 Crystal Growth and Design 20 Billy Chabalenge, Sachin Korde, Adrian L Kelly, Daniel Neagu and Anant Paradkar ACS https://doi.org/10.1021/acs.cgd.0c00338
Mechanistic Understanding of Competitive Destabilization of Carbamazepine Cocrystals under Solvent Free Conditions 2020 CRYSTAL GROWTH & DESIGN (ONLINE) https://doi.org/10.1021/acs.cgd.0c00735 MHD Bashir Alsirawan, Xiaojun Lai, Rafel Prohens, Venu R. Vangala, Petroc Shelley, Thomas J. Bannan, David O. Topping, and Anant Paradkar https://doi.org/10.1021/acs.cgd.0c00735
Mechanistic Understanding of Competitive Destabilization of Carbamazepine Cocrystals under Solvent Free Conditions 2020 CRYSTAL GROWTH & DESIGN (ONLINE) https://doi.org/10.1021/acs.cgd.0c00735 MHD Bashir Alsirawan, Xiaojun Lai, Rafel Prohens, Venu R. Vangala, Petroc Shelley, Thomas J. Bannan, David O. Topping, and Anant Paradkar https://doi.org/10.1021/acs.cgd.0c00735
Nicotinamide extrudates as novel anti-aging and collagen promoting platform: a comparative cosmeceutical study versus the gel form 2020 Pharmaceutical Development and Technology Alyoussef A.;Nasr M.;Ahmed R.F.;Ahmed Farid O.A.H.;Bakeer R.;Karandikar H.;Paradkar A. 1083-7450 10.1080/10837450.2020.1803908
Solid-State Competitive Destabilization of Caffeine Malonic Acid cocrystal: Mechanistic and Kinetic Investigation 2020 Crystal Growth and Design DOI: 10.1021/acs.cgd.0c01246 M. Bashir Alsirawan, Xiaojun Lai, Rafel Prohens, Venu Vangala, Sudhir Pagire, Petro Shelley, Thomas Bannan, David Topping, and Anant Paradkar American Chemical Society DOI: 10.1021/acs.cgd.0c01246
Continuous Manufacturing of Cocrystals Using Solid State Shear Milling Technology 2018 Crystal Growth and Design 18 2297 - 2304 Korde, S.; Pagire, S.; Pan, H.; Seaton, C.; Kelly, A.; Chen, Y.; Wang, Q.; Coates, P.; Paradkar, A. https://doi.org/10.1021/acs.cgd.7b01733
In-process rheometry as a PAT tool for hot melt extrusion 2018 Drug Development and Industrial Pharmacy 44 Kelly, A.; Gough, T.; Isreb, M.; Dhumal, R. S.; Jones, J. W.; Nicholson, S.; Dennis, A. B.; Paradkar, A. https://doi.org/10.1080/03639045.2017.1408641
In vivo and in vitro antioxidant activity of lipid based extract of Bacopa monniera Linn. compared to conventional extract and traditional preparation 2010 European Journal of Integrative Medicine 2 93 - 101 Sathiyanarayanan L.;Paradkar A.R.;Mahadik K.R. 1876-3820 10.1016/j.eujim.2009.12.003
Cocrystalization and simultaneous agglomeration using hot melt extrusion 2010 Pharmaceutical Research Paradkar, A.;Dhumal, R.S.;Kelly, A.L.;York, P.;Coates, P.D.; 10.1007/s11095-010-0273-9
Shear and extensional rheology of hydroxypropyl cellulose melt using capillary rheometry 2009 Journal of Pharmaceutical and Biomedical Analysis Paradkar, A.;Kelly, A.;Coates, P.;York, P.; 10.1016/j.jpba.2008.11.014
Mechanism of Hydrogen-Bonded Complex Formation between Ibuprofen and Nanocrystalline Hydroxyapatite 2017 Langmuir Ryabenkova, Y.;Jadav, N.;Conte, M.;Hippler, M.F.A.;Reeves-Mclaren, N.;Coates, P.D.;Twigg, P.;Paradkar, A.; 10.1021/acs.langmuir.6b04510
Effect of Ultrasound on Molecular Structure Development of Polylactide 2014 Polymer - Plastics Technology and Engineering Bao, W.;Wu, H.;Guo, S.;Paradkar, A.;Kelly, A.;Brown, E.;Coates, P.; 10.1080/03602559.2014.886062
Aqueous and pH Dependent Coacervation Method for Taste Masking of Paracetamol via Amorphous Solid Dispersion Formation 2021 Scientific Reports xx Basheer Al-kasmi, M. Bashir Alsirawan, Anant Paradkar, Abdulhakim Nattouf, and Hind El-zein Nature
Interfacial Cocrystallization Using Oily Phase via Liquid−Liquid Phase Separation 2022 CRYSTAL GROWTH & DESIGN (ONLINE) 22 M. Asim Sajid Al-Hanafi, Mhd Bashir Alsirawan, Colin C. Seaton, Thomas Swift, Sudhir Pagire, Venu R. Vangala, Adrian L. Kelly, and Anant Paradkar https://doi.org/10.1021/acs.cgd.2c00263
In situ monitoring of competitive coformer exchange reaction by 1H MAS Solid-state NMR 2024 Molecular Pharmaceutics In Press Chaithanya Hareendran, Bashir Alsirawan, Anant Paradkar, and T.G. Ajithkumar American Chemical Society https://pubs.acs.org/doi/epdf/10.1021/acs.molpharmaceut.3c01118