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Dr Stacy-Paul Wilshaw

Assistant Professor

Faculty/Dept/School School of Pharmacy and Medical Sciences
(Faculty of Life Sciences)
Emails.wilshaw@bradford.ac.uk
Telephone +441274 236017

Research

Acellular biological scaffolds for tissue repair and regeneration. 

A range of acellular biological scaffolds have been developed which may have clinical application for repair and regeneration, as in vitro models of disease or applied to in vitro drug screening. These biological scaffolds are devoid of cells and cell remnants and have demonstrated a capacity for regeneration however the role of the body’s immune system in the regenerative process is largely unknown. Current research focuses on the application of acellular scaffolds for cardiovascular repair and peripheral nerve replacement, alongside the development of liver grafts and the application of human amniotic membrane to restore damaged cornea and as a cell carrier. Elucidating the mechanisms though which acellular scaffolds regenerate in vivo and the role of the immune system in this process.

Publications

TitleRecovery of low volumes of wear debris from rat stifle joint tissues using a novel particle isolation method (2018)
AuthorsPatel, J.; Lal, S.; Nuss, K.; Wilshaw, Stacy-Paul; von Rechenberg, B.; Hall, R.M.; Tipper, J.L.
 
TitleDevelopment and characterisation of a large diameter decellularised vascular allograft (2018)
AuthorsAldridge, A.; Desai, A.; Owston, H.; Jennings, L.M.; Fisher, J.; Rooney, P.; Kearney, J.N.; Ingham, E.; Wilshaw, Stacy-Paul
 
TitleValidation of a novel particle isolation procedure using particle doped tissue samples (2018)
AuthorsPatel, J.; Lal, S.; Wilshaw, Stacy-Paul; Hall, R.M.; Tipper, J.L.
 
TitleGamma-irradiated human amniotic membrane decellularised with sodium dodecyl sulfate is a more efficient substrate for the ex vivo expansion of limbal stem cells (2017)
AuthorsFigueiredo, G.S.; Bojic, S.; Rooney, P.; Wilshaw, Stacy-Paul; Connon, C.J.; Gouveia, R.M.; Paterson, C.; Lepert, G.; Mudhar, H.S.; Figueiredo, F.C.; Lako, M.
 
TitleDecellularisation and histological characterisation of porcine peripheral nerves (2016)
AuthorsZilic, L.; Wilshaw, Stacy-Paul; Haycock, J.W.
 
TitleAn anatomical study of porcine peripheral nerve and its potential use in nerve tissue engineering (2015)
AuthorsZilic, L.; Garner, P.E.; Yu, Tong; Roman, S.; Haycock, J.W.; Wilshaw, Stacy-Paul
 
TitleDevelopment and Characterization of Acellular Porcine Pulmonary Valve Scaffolds for Tissue Engineering (2014)
AuthorsLuo, J.; Korossis, S.A.; Wilshaw, Stacy-Paul; Jennings, L.M.; Fisher, J.; Ingham, E.
 
TitleAssessment of the antimicrobial activity of acellular vascular grafts (2012)
AuthorsOwen K.;Wilshaw S.;Homer-Vanniasinkam S.;Bojar R.;Berry H.;Ingham E.
JournalEuropean journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
DOI10.1016/j.ejvs.2012.01.027
 
TitleDevelopment and characterization of acellular allogeneic arterial matrices. (2012)
AuthorsWilshaw SP;Rooney P;Berry H;Kearney JN;Homer-Vanniasinkam S;Fisher J;Ingham E;
JournalTissue Engineering - Part A.
DOI10.1089/ten.tea.2011.0287
 
TitleThe use of antithrombotic therapies in reducing synthetic small-diameter vascular graft thrombosis. (2012)
AuthorsTatterton M;Wilshaw SP;Ingham E;Homer-Vanniasinkam S;
JournalVascular and Endovascular Surgery
DOI10.1177/1538574411433299
 
TitleCytocompatibility of poly(1,2 propandiol methacrylate) copolymer hydrogels and conetworks with or without alkyl amine functionality (2009)
AuthorsRimmer S.;Wilshaw S.;Pickavance P.;Ingham E.
JournalBiomaterials
DOI10.1016/j.biomaterials.2009.01.041
 
TitleInvestigation of the antiadhesive properties of human mesothelial cells cultured in vitro on implantable surgical materials (2009)
AuthorsWilshaw S.;Burke D.;Fisher J.;Ingham E.
JournalJournal of Biomedical Materials Research - Part B Applied Biomaterials
DOI10.1002/jbm.b.31148
 
TitleFactors influencing the oxygen consumption rate of aortic valve interstitial cells: application to tissue engineering. (2009)
AuthorsWang L;Wilshaw SP;Korossis S;Fisher J;Jin Z;Ingham E;
JournalTissue Engineering - Part C: Methods
DOI10.1089/ten.tec.2008.0415
 
TitleThe effect of amniotic membrane preparation method on its ability to serve as a substrate for the ex-vivo expansion of limbal epithelial cells. (2009)
AuthorsShortt AJ;Secker GA;Lomas RJ;Wilshaw SP;Kearney JN;Tuft SJ;Daniels JT;
JournalBiomaterials
DOI10.1016/j.biomaterials.2008.10.048