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Dr Sriharsha Kantamneni

Associate Professor

Faculty/Dept/School School of Pharmacy and Medical Sciences
(Faculty of Life Sciences)
Telephone +441274 236072


Date Role Title / Description Funder Award
01-MAY-17 - PIESCRT proteins as therapeutic targets in Alzheimers disease
04-FEB-16 - PIMechanisms regulating NMDA-mediated down-regulation of neuronal GABAB receptors in ischemia
01-FEB-16 - Co-PIReal-time imaging of molecular mechanisms underlying synaptic dysfunction and neurodegeneration in Alzheimer’s disease
01-APR-18 - PIThe SOCS3/TBK1 interface: Development of novel therapeutics to prevent MND and neurodegeneration
30-NOV-18 - 01-DEC-19Co-PISelfSeal: A Novel Powder Haemostat Spray
01-JUL-19 - 30-JUN-20Co-PISelf-Lift: An innovative formulation for polyp lifting based on SelfGel Platform
10-DEC-17 - PIMolecular mechanisms underlying chemerin receptor (CMKLR1) signalling pathways, trafficking and regulation in novel hypothalamic neuronal cell line

Professional activities

  • 01-JAN-98: DR. MGR Medical University, India - Bachelors
  • 01-JAN-00: Sheffield Hallam University - MSc
  • 01-JAN-04: University of Bristol - PhD
  • 01-JAN-06: City of Bristol College - APD
  • 01-JAN-15: University of Bradford - postgraduate certificate
  • 01-JAN-11: King Faisal Specialist Hospital, Riyadh, Saudi Arabia - Research Fellow
  • 01-JAN-05: University of Bristol - Research Associate
  • Member of Biochemical Society,
  • Member of British Neuroscience Association,
  • Member of British Pharmacological Society,
  • Member of British Society for Cell Biology,
  • Member of International Society for Neurochemistry,
  • General Administration: MPharm Admission Tutor and On-campus events lead
  • General Administration: UK-China Neuroprotection Research Platform Coordinator
  • Module Leader: Molecules to Systems PHA4008-C
  • Programme & Module Management: MPharmacy Stage 1 Leader


TitleModulation of neurotransmission by the GABABreceptor (2016)
AuthorsKantamneni S.
TitleCross-talk and regulation between glutamate and GABAB receptors (2015)
AuthorsKantamneni, Sriharsha
TitleDifferential regulation of GABAB receptor trafficking by different modes of N-methyl-D-aspartate (NMDA) receptor signaling (2014)
AuthorsKantamneni, Sriharsha; Gonzàlez-Gonzàlez, I.M.; Luo, J.; Cimarosti, H.; Jacobs, S.C.; Jaafari, N.; Henley, J.M.
TitleSUMOylation Is Required for Glycine-Induced Increases in AMPA Receptor Surface Expression (ChemLTP) in Hippocampal Neurons (2013)
AuthorsJaafari, N.; Konopacki, F.A.; Owen, T.F.; Kantamneni, Sriharsha; Rubin, P.; Craig, T.J.; Wilkinson, K.A.; Henley, J.M.
TitleSUMOylation and phosphorylation of GluK2 regulate kainate receptor trafficking and synaptic plasticity (2012)
AuthorsChamberlain, S.E.; Gonzàlez-Gonzàlez, I.M.; Wilkinson, K.A.; Konopacki, F.A.; Kantamneni, Sriharsha; Henley, J.M.; Mellor, J.R.
TitleAgonist-induced PKC phosphorylation regulates GluK2 SUMOylation and kainate receptor endocytosis (2011)
AuthorsKonopacki, F.A.; Jaafari, N.; Rocca, D.L.; Wilkinson, K.A.; Chamberlain, S.E.; Rubin, P.; Kantamneni, Sriharsha; Mellor, J.R.; Henley, J.M.
TitleActivity-dependent SUMOylation of the brain-specific scaffolding protein GISP. (2011)
AuthorsKantamneni S;Wilkinson KA;Jaafari N;Ashikaga E;Rocca D;Rubin P;Jacobs SC;Nishimune A;Henley JM;
JournalBiochemical and Biophysical Research Communications
TitleStudy of novel selective mGlu2 agonist in the temporo-ammonic input to CA1 neurons reveals reduced mGlu2 receptor expression in a Wistar substrain with an anxiety-like phenotype. (2011)
AuthorsCeolin L;Kantamneni S;Barker GR;Hanna L;Murray L;Warburton EC;Robinson ES;Monn JA;Fitzjohn SM;Collingridge GL;Bortolotto ZA;Lodge D;
JournalThe Journal of neuroscience : the official journal of the Society for Neuroscience
TitleGISP increases neurotransmitter receptor stability by down-regulating ESCRT-mediated lysosomal degradation. (2009)
AuthorsKantamneni S;Holman D;Wilkinson KA;Nishimune A;Henley JM;
JournalNeuroscience Letters
TitleIschaemia differentially regulates GABA(B) receptor subunits in organotypic hippocampal slice cultures. (2009)
AuthorsCimarosti H;Kantamneni S;Henley JM;
TitleGISP binding to TSG101 increases GABA receptor stability by down-regulating ESCRT-mediated lysosomal degradation. (2008)
AuthorsKantamneni S;Holman D;Wilkinson KA;Corrêa SA;Feligioni M;Ogden S;Fraser W;Nishimune A;Henley JM;
JournalJournal of Neurochemistry
TitleGISP: a novel brain-specific protein that promotes surface expression and function of GABA(B) receptors. (2007)
AuthorsKantamneni S;Corrêa SA;Hodgkinson GK;Meyer G;Vinh NN;Henley JM;Nishimune A;
JournalJournal of Neurochemistry
TitleModulation of Neurotransmission by the GABAB Receptor (2016)
AuthorsKantamneni, Sriharsha
Other typeEditorial
TitleEditorial: Cerebrovascular and Neurodegenerative Diseases - New Insights Into Molecular Cell Biology and Therapeutic Targets (2019)
AuthorsSaha S.;Kantamneni S.
JournalFrontiers in Neurology