| Title | The role of MT1-MMP in the progression and metastasis of osteosarcoma (2022) |
|---|
| Authors | Spencer, H.L.M.; Shnyder, S.D.; Loadman, P.M.; Falconer, R.A. |
|---|
| Journal | Journal of Cancer Metastasis and Treatment |
|---|
| DOI | DOI:10.20517/2394-4722.2021.174 |
|---|
| |
| Title | Semi-Synthetic Analogues of Cryptolepine as a Potential Source of Sustainable Drugs for the Treatment of Malaria, Human African Trypanosomiasis and Cancer (2022) |
|---|
| Authors | Abacha, YZ; Donkor Forkuo, A; Gbedema, SY; Mittal, N; Ottilie, S; Rocamora, F; Winzeler, EA; van Schalkwyk, DA; Kelly, JM; Taylor, MC; Reader, J; Birkholtz, L-M; Lisgarten, DR; Cockcroft, JK; Lisgarten, JN; Palmer, RA; Talbert, RC; Shnyder, SD, Wright, CW |
|---|
| Journal | Frontiers in Pharmacology |
|---|
| DOI | doi: 10.3389/fphar.2022.875647 |
|---|
| |
| Title | Cytochrome P450 isoforms 1A1, 1B1 AND 2W1 as targets for therapeutic intervention in head and neck cancer. (2021) |
|---|
| Authors | Presa D;Khurram SA;Zubir AZA;Smarakan S;Cooper PA;Morais GR;Sadiq M;Sutherland M;Loadman PM;McCaul J;Shnyder SD;Patterson LH;Pors K; |
|---|
| Journal | Scientific Reports |
|---|
| DOI | 10.1038/s41598-021-98217-z |
|---|
| |
| Title | Probing cytochrome P450 (CYP) bioactivation with chloromethylindoline bioprecursors derived from the duocarmycin family of compounds. (2021) |
|---|
| Authors | Ortuzar N;Karu K;Presa D;Morais GR;Sheldrake HM;Shnyder SD;Barnieh FM;Loadman PM;Patterson LH;Pors K;Searcey M; |
|---|
| Journal | Bioorganic and Medicinal Chemistry |
|---|
| DOI | 10.1016/j.bmc.2021.116167 |
|---|
| |
| Title | An assay for quantitative analysis of polysialic acid expression in cancer cells (2021) |
|---|
| Authors | Guo, X.; Elkashef, S.M.; Patel, A.; Ribeiro Morais, G.; Shnyder S.D.; Loadman, P.M.; Patterson, L.H.; Falconer, R.A. |
|---|
| Journal | Carbohydrate Polymers |
|---|
| DOI | 10.1016/j.carbpol.2021.117741 |
|---|
| |
| Title | Application of Small Molecule FPR1 Antagonists in the Treatment of Cancers (2020) |
|---|
| Authors | Djevdet S. Ahmet, Haneen A. Basheer, Anwar Salem, Di Lu, Amin Aghamohammadi, Patrick Weyerhäuser, Andrea Bordiga, Juman Almeniawi, Sabah Rashid, Patricia A. Cooper, Steven D. Shnyder, Victoria Vinader, and Kamyar Afarinkia |
|---|
| Journal | Scientific Reports |
|---|
| Publisher | Nature |
|---|
| DOI | https://doi.org/10.1038/s41598-020-74350-z |
|---|
| |
| Title | An efficient assay for identification and quantitative evaluation of potential polysialyltransferase inhibitors. (2020) |
|---|
| Authors | Guo X; Malcolm J.R.; Ali M.M.; Ribeiro Morais G; Shnyder S.D.; Loadman P.M.; Patterson L.H.; Falconer R.A. |
|---|
| Journal | ANALYST (PRINT) |
|---|
| DOI | 10.1039/d0an00721h |
|---|
| |
| Title | Preclinical Anticancer Activity of an Electron-Deficient Organoruthenium(II) Complex (2020) |
|---|
| Authors | Soldevila-Barreda J.J.;Azmanova M.;Pitto-Barry A.;Cooper P.A.;Shnyder S.D.;Barry N.P.E. |
|---|
| Journal | ChemMedChem |
|---|
| DOI | 10.1002/cmdc.202000096 |
|---|
| |
| Title | Tumor growth suppression using a combination of taxol-based therapy and GSK3 inhibition in non-small cell lung cancer (2019) |
|---|
| Authors | O'Flaherty, L.; Shnyder, Steven D.; Cooper, Patricia A.; Cross, S.J.; Wakefield, J.G.; Pardo, O.E.; Seckl, M.J.; Tavare, J.M. |
|---|
| |
| Title | Hypoxia modulates CCR7 expression in head and neck cancers (2018) |
|---|
| Authors | Basheer, Haneen A.; Pakanavicius, E.; Cooper, Patricia A.; Shnyder, Steven D.; Martin, L.; Hunter, K.D.; Vinader, Victoria; Afarinkia, Kamyar |
|---|
| |
| Title | Preclinical anti-cancer activity and multiple mechanisms of action of a cationic silver complex bearing N-heterocyclic carbene ligands (2017) |
|---|
| Authors | Allison, Simon J.; Sadiq, Maria; Baronou, Efstathia; Cooper, Patricia A.; Dunnill, C.; Georgopoulos, N.T.; Latif, A.; Shepherd, S.L.; Shnyder, Steven D.; Stratford, I.J.; Wheelhouse, Richard T.; Willans, C.; Phillips, Roger M. |
|---|
| Journal | Cancer Letters |
|---|
| |
| Title | Tubulin-binding dibenz[c,e]oxepines. Part 2. 1 Structural variation and biological evaluation as tumour vasculature disrupting agents (2017) |
|---|
| Authors | Rossington, S.B.; Hadfield, J.A.; Shnyder, Steven D.; Wallace, T.W.; Williams, K.J. |
|---|
| |
| Title | Tubulin-binding dibenz[c,e]oxepines: Part 2.1Structural variation and biological evaluation as tumour vasculature disrupting agents (2017) |
|---|
| Authors | Rossington S.;Hadfield J.;Shnyder S.;Wallace T.;Williams K. |
|---|
| Journal | Bioorganic and Medicinal Chemistry |
|---|
| DOI | 10.1016/j.bmc.2017.01.027 |
|---|
| |
| Title | Agarose Spot as a Comparative Method for in situ Analysis of Simultaneous Chemotactic Responses to Multiple Chemokines (2017) |
|---|
| Authors | Ahmed, Mohaned S.A.; Basheer, Haneen A.; Ayuso, J.M.; Ahmet, Djevdet; Mazzini, Marco; Patel, Roshan; Shnyder, Steven D.; Vinader, Victoria; Afarinkia, Kamyar |
|---|
| |
| Title | RGD-Binding Integrins in Head and Neck Cancers (2017) |
|---|
| Authors | Ahmedah, H.T.; Patterson, Laurence H.; Shnyder, Steven D.; Sheldrake, Helen M. |
|---|
| |
| Title | The Effect of Polysialic Acid Expression on Glioma Cell Nano-mechanics (2016) |
|---|
| Authors | Grant, Colin A.; Twigg, Peter C.; Saeed, Rida F.; Lawson, G.; Falconer, Robert A.; Shnyder, Steven D. |
|---|
| Journal | BioNanoScience |
|---|
| DOI | 10.1007/s12668-016-0192-2 |
|---|
| |
| Title | PIK3CA dependence and sensitivity to therapeutic targeting in urothelial carcinoma (2016) |
|---|
| Authors | Ross, R.L.; McPherson, H.R.; Kettlewell, L.; Shnyder, Steven D.; Hurst, C.D.; Alder, O.; Knowles, M.A. |
|---|
| |
| Title | The use of thermographic imaging to evaluate therapeutic response in human tumour xenograft models (2016) |
|---|
| Authors | Hussain, Nosheen; Connah, David; Ugail, Hassan; Cooper, Patricia A.; Falconer, Robert A.; Patterson, Laurence H.; Shnyder, Steven D. |
|---|
| Journal | Scientific Reports |
|---|
| DOI | 10.1038/srep31136 |
|---|
| |
| Title | Probing cytochrome P450-mediated activation with a truncated azinomycin analogue (2015) |
|---|
| Authors | Vinader, Victoria; Sadiq, Maria; Sutherland, Mark H.; Huang, M.Y.; Loadman, Paul M.; Elsalem, Lina M.I.; Shnyder, Steven D.; Cui, H.J.; Afarinkia, Kamyar; Searcey, M.; Patterson, Laurence H.; Pors, Klaus |
|---|
| Journal | MedChemComm |
|---|
| DOI | dx.doi.org/10.1039/c4md00411f |
|---|
| |
| Title | Thin-layer chromatography/matrix-assisted laser desorption/ionisation mass spectrometry and matrix-assisted laser desorption/ionisation mass spectrometry imaging for the analysis of phospholipids in LS174T colorectal adenocarcinoma xenografts treated with the vascular disrupting agent DMXAA (2015) |
|---|
| Authors | Batubara, A.; Carolan, V.A.; Loadman, Paul M.; Sutton, Chris W.; Shnyder, Steven D.; Clench, M.R. |
|---|
| Journal | Rapid Communications In Mass Spectrometry |
|---|
| DOI | doi.org/10.1002/rcm.7223 |
|---|
| |
| Title | Study of the chemotactic response of multicellular spheroids in a microfluidic device (2015) |
|---|
| Authors | Ayuso, J.M.; Basheer, Haneen A.; Monge, R.; Sánchez-Álvarez, P.; Doblare, M.; Shnyder, Steven D.; Vinader, Victoria; Afarinkia, Kamyar; Fernandez, L.J.; Ochoa, I. |
|---|
| |
| Title | Potent organometallic osmium compounds induce mitochondria-mediated apoptosis and S-phase cell cycle arrest in A549 non-small cell lung cancer cells (2014) |
|---|
| Authors | van Rijt, S.H.; Romero-Canelón, I.; Fu, Y.; Shnyder, Steven D.; Sadler, P.J. |
|---|
| |
| Title | Tumor-Targeted Prodrug ICT2588 Demonstrates Therapeutic Activity Against Solid Tumors and Reduced Potential For Cardiovascular Toxicity (2014) |
|---|
| Authors | Gill, Jason H.; Loadman, Paul M.; Shnyder, Steven D.; Cooper, Patricia A.; Atkinson, Jennifer M.; Ribeiro Morais, Goreti; Patterson, Laurence H.; Falconer, Robert A. |
|---|
| Journal | Molecular Cancer Therapeutics |
|---|
| DOI | 10.1021/mp400760b |
|---|
| |
| Title | Colon cancer-specific cytochrome P450 2W1 converts duocarmycin analogues into potent tumor cytotoxins (2013) |
|---|
| Authors | Travica, S.; Pors, Klaus; Loadman, Paul M.; Shnyder, Steven D.; Johansson, I.; Alandas, Mohammed N.; Sheldrake, Helen M.; Mkrtchian, S.; Patterson, Laurence H.; Ingelman-Sundberg, M. |
|---|
| |
| Title | Targeting of Hypoxia in AQ4N-treated Tumour Xenografts by MALDI-Ion Mobility Separation-Mass Spectrometry Imaging (2013) |
|---|
| Authors | Djidja, M-C.; Francese, S.; Claude, E.; Loadman, Paul M.; Sutton, Chris W.; Shnyder, Steven D.; Cooper, Patricia A.; Patterson, Laurence H.; Carolan, V.A.; Clench, M.R. |
|---|
| |
| Title | Parallel RNA interference screens identify EGFR activation as an escape mechanism in FGFR3-mutant cancer (2013) |
|---|
| Authors | Herrera-Abreu, M.T.; Pearson, A.; Campbell, J.; Shnyder, Steven D.; Knowles, M.A.; Ashworth, A.; Turner, N.C. |
|---|
| |
| Title | Re-engineering of the Duocarmycin Structural Architecture Enables Bioprecursor Development Targeting CYP1A1 and CYP2W1 for Biological Activity (2013) |
|---|
| Authors | Sheldrake, Helen M.; Travica, S.; Johansson, I.; Loadman, Paul M.; Sutherland, Mark H.; Elsalem, Lina M.I.; Illingworth, Nicola A.; Cresswell, Alexander J.; Reuillon, Tristan; Shnyder, Steven D.; Mkrtchian, S.; Searcey, M.; Ingelman-Sundberg, M.; Patterson, Laurence H.; Pors, Klaus |
|---|
| |
| Title | NCAM polysialylation during adherence transitions: Live cell monitoring using an antibody-mimetic EGFP-endosialidase and the viability dye DRAQ7 (2013) |
|---|
| Authors | Smith P.;Furon E.;Wiltshire M.;Chappell S.;Patterson L.;Shnyder S.;Falconer R.;Errington R. |
|---|
| Journal | Cytometry Part A |
|---|
| DOI | 10.1002/cyto.a.22306 |
|---|
| |
| Title | Pharmacological Inhibition of polysialyltransferase ST8SiaII Modulates Tumour Cell Migration (2013) |
|---|
| Authors | Al-Saraireh, Yousef M.J.; Sutherland, Mark H.; Springett, Bradley R.; Freiberger, F.; Ribeiro Morais, Goreti; Loadman, Paul M.; Errington, R.J.; Smith, P.J.; Fukuda, M.; Gerardy-Schahn, R.; Patterson, Laurence H.; Shnyder, Steven D.; Falconer, Robert A. |
|---|
| Journal | PLoS ONE |
|---|
| DOI | 10.1371/journal.pone.0073366 |
|---|
| |
| Title | Antitumor activity of a duocarmycin analogue rationalized to be metabolically activated by cytochrome P450 1A1 in human transitional cell carcinoma of the bladder (2013) |
|---|
| Authors | Sutherland, Mark H.; Gill, Jason H.; Loadman, Paul M.; Laye, Jonathan P.; Sheldrake, Helen M.; Illingworth, Nicola A.; Alandas, Mohammed N.; Cooper, Patricia A.; Searcey, M.; Pors, Klaus; Shnyder, Steven D.; Patterson, Laurence H. |
|---|
| |
| Title | Polysialyltransferase: A new target in metastatic cancer (2012) |
|---|
| Authors | Falconer R.;Errington R.;Shnyder S.;Smith P.;Patterson L. |
|---|
| Journal | Current Cancer Drug Targets |
|---|
| DOI | 10.2174/156800912803251225 |
|---|
| |
| Title | Synthesis and biological evaluation of colchicine C-ring analogues tethered with aliphatic linkers suitable for prodrug derivatisation (2012) |
|---|
| Authors | Fournier-Dit-Chabert J.;Vinader V.;Santos A.;Redondo-Horcajo M.;Dreneau A.;Basak R.;Cosentino L.;Marston G.;Abdel-Rahman H.;Loadman P.;Shnyder S.;Díaz J.;Barasoain I.;Falconer R.;Pors K. |
|---|
| Journal | Bioorganic and Medicinal Chemistry Letters |
|---|
| DOI | 10.1016/j.bmcl.2012.09.104 |
|---|
| |
| Title | Synthesis and biological evaluation of colchicine B-ring analogues tethered with halogenated benzyl moieties (2012) |
|---|
| Authors | Cosentino L.;Redondo-Horcajo M.;Zhao Y.;Santos A.;Chowdury K.;Vinader V.;Abdallah Q.;Abdel-Rahman H.;Fournier-Dit-Chabert J.;Shnyder S.;Loadman P.;Fang W.;Díaz J.;Barasoain I.;Burns P.;Pors K. |
|---|
| Journal | Journal of Medicinal Chemistry |
|---|
| DOI | 10.1021/jm301151t |
|---|
| |
| Title | Anti-colorectal cancer activity of an organometallic osmium arene azopyridine complex (2011) |
|---|
| Authors | Shnyder S.;Fu Y.;Habtemariam A.;Van Rijt S.;Cooper P.;Loadman P.;Sadler P. |
|---|
| Journal | MedChemComm |
|---|
| DOI | 10.1039/c1md00075f |
|---|
| |
| Title | An agarose spot chemotaxis assay for chemokine receptor antagonists (2011) |
|---|
| Authors | Vinader V.;Al-Saraireh Y.;Wiggins H.;Rappoport J.;Shnyder S.;Patterson L.;Afarinkia K. |
|---|
| Journal | Journal of Pharmacological and Toxicological Methods |
|---|
| DOI | 10.1016/j.vascn.2011.01.004 |
|---|
| |
| Title | Modification of the duocarmycin pharmacophore enables CYP1A1 targeting for biological activity (2011) |
|---|
| Authors | Pors, Klaus; Loadman, Paul M.; Shnyder, Steven D.; Sutherland, Mark H.; Sheldrake, Helen M.; Guino, M.; Kiakos, K.; Hartley, J.A.; Searcey, M.; Patterson, Laurence H. |
|---|
| |
| Title | Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo (2011) |
|---|
| Authors | Lamont, F.R.; Tomlinson, D.C.; Cooper, Patricia A.; Shnyder, Steven D.; Chester, J.D.; Knowles, M.A. |
|---|
| |
| Title | The microtubule depolymerizing agent CYT997 causes extensive ablation of tumor vasculature in vivo (2011) |
|---|
| Authors | Burns, C.J.; Fantino, E.; Powell, A.K.; Shnyder, Steven D.; Cooper, Patricia A.; Nelson, S.; Christophi, C.; Malcontenti-Wilson, C.; Dubljevic, V.; Harte, M.F.; Joffe, M.; Phillips, I.D.; Segal, D.; Wilks, A.F.; Smith, G.D. |
|---|
| |
| Title | Adenovirus-mediated hypoxia-targeted gene therapy using HSV thymidine kinase and bacterial nitroreductase prodrug-activating genes in vitro and in vivo (2011) |
|---|
| Authors | Harvey T.;Hennig I.;Shnyder S.;Cooper P.;Ingram N.;Hall G.;Selby P.;Chester J. |
|---|
| Journal | Cancer Gene Therapy |
|---|
| DOI | 10.1038/cgt.2011.43 |
|---|
| |
| Title | Use of the hollow fiber assay for the evaluation of DNA damaging agents (2011) |
|---|
| Authors | Veiga J.;Cooper P.;Pors K.;Patterson L.;Bibby M.;Shnyder S. |
|---|
| Journal | Journal of Pharmacological and Toxicological Methods |
|---|
| DOI | 10.1016/j.vascn.2011.04.006 |
|---|
| |
| Title | Organometallic osmium arene complexes with potent cancer cell cytotoxicity (2010) |
|---|
| Authors | Fu Y.;Habtemariam A.;Pizarro A.;Van Rijt S.;Healey D.;Cooper P.;Shnyder S.;Clarkson G.;Sadler P. |
|---|
| Journal | Journal of Medicinal Chemistry |
|---|
| DOI | 10.1021/jm100560f |
|---|
| |
| Title | Development of a novel tumor-targeted vascular disrupting agent activated by membrane-type matrix metalloproteinases (2010) |
|---|
| Authors | Atkinson J.;Falconer R.;Edwards D.;Pennington C.;Siller C.;Shnyder S.;Bibby M.;Patterson L.;Loadman P.;Gill J. |
|---|
| Journal | Cancer Research |
|---|
| DOI | 10.1158/0008-5472.CAN-10-1440 |
|---|
| |
| Title | Improved preparation and detection of cytochrome P450 isoforms using MS methods (2010) |
|---|
| Authors | Sutton C.;Sutherland M.;Shnyder S.;Patterson L. |
|---|
| Journal | Proteomics |
|---|
| DOI | 10.1002/pmic.200900489 |
|---|
| |
| Title | Retargeted adenoviral cancer gene therapy for tumour cells overexpressing epidermal growth factor receptor or urokinase-type plasminogen activator receptor (2010) |
|---|
| Authors | Harvey T.;Burdon D.;Steele L.;Ingram N.;Hall G.;Selby P.;Vile R.;Cooper P.;Shnyder S.;Chester J. |
|---|
| Journal | Gene Therapy |
|---|
| DOI | 10.1038/gt.2010.45 |
|---|
| |
| Title | Development of a novel tumor-targeted vascular disrupting agent activated by Membrane-type Matrix Metalloproteinases (MT-MMPs) (2010) |
|---|
| Authors | Atkinson, Jennifer M.; Falconer, Robert A.; Edwards, D.R.; Pennington, C.J.; Siller, Catherine S.; Shnyder, Steven D.; Bibby, Michael C.; Patterson, Laurence H.; Loadman, Paul M.; Gill, Jason H. |
|---|
| |
| Title | Development of a modified hollow fibre assay for studying agents targeting the tumour neovasculature. (2009) |
|---|
| Authors | Shnyder, Steven D.; Jubb, E.; Hasan, J.; Cooper, Patricia A.; Bibby, Michael C.; Jayson, G.C.; Pilarinou, E. |
|---|
| |
| Title | In vivo activation of the hypoxia-targeted cytotoxin AQ4N in human tumor xenograft. (2009) |
|---|
| Authors | Williams, K.J.; Albertella, M.R.; Fitzpatrick, B.; Loadman, Paul M.; Shnyder, Steven D.; Chinje, E.C.; Telfer, B.A.; Dunk, C.R.; Harris, P.A.; Stratford, I.J. |
|---|
| |
| Title | In vivo activation of the hypoxia-targeted cytotoxin AQ4N in human tumor xenografts (2009) |
|---|
| Authors | Williams K.;Albertella M.;Fitzpatrick B.;Loadman P.;Shnyder S.;Chinje E.;Telfer B.;Dunk C.;Harris P.;Stratford I. |
|---|
| Journal | Molecular Cancer Therapeutics |
|---|
| DOI | 10.1158/1535-7163.MCT-09-0396 |
|---|
| |
| Title | Fibroblast growth factor receptor 1 promotes proliferation and survival via activation of the mitogen-activated protein kinase pathway in bladder cancer (2009) |
|---|
| Authors | Tomlinson, D.C.; Lamont, F.R.; Shnyder, Steven D.; Knowles, M.A. |
|---|
| |
| Title | Use of the hollow fibre assay for studies of tumor neovasculature. (2009) |
|---|
| Authors | Shnyder S. |
|---|
| Journal | Methods in molecular biology (Clifton, N.J.) |
|---|
| DOI | 10.1007/978-1-59745-241-0_21 |
|---|
| |
| Title | Single-chain TNF, a TNF derivative with enhanced stability and antitumoral activity (2008) |
|---|
| Authors | Krippner-Heidenreich A.;Grunwald I.;Zimmermann G.;Kühnle M.;Gerspach J.;Sterns T.;Shnyder S.;Gill J.;Männel D.;Pfizenmaier K.;Scheurich P. |
|---|
| Journal | Journal of Immunology |
|---|
| DOI | 10.4049/jimmunol.180.12.8176 |
|---|
| |
| Title | A cytotoxic diterpenoid from Croton membranaceus, the major constituent of anticancer herbal formulations used in Ghana (2008) |
|---|
| Authors | Bayor, M.T.;Ayim, J.S.K.;Marston, G.;Phillips, R.M.;Shnyder, S.D.;Wheelhouse, R.T.;Wright, C.W.; |
|---|
| Journal | Natural product communications |
|---|
| |
| Title | Sodium pancratistatin 3,4-O-cyclic phosphate, a water-soluble synthetic derivative of pancratistatin, is highly effective in a human colon tumor model (2008) |
|---|
| Authors | Shnyder S.;Cooper P.;Millington N.;Gill J.;Bibby M. |
|---|
| Journal | Journal of Natural Products |
|---|
| DOI | 10.1021/np070477p |
|---|
| |
| Title | Triplex profiling of functionally distinct chaperones (ERp29/PDI/BiP) reveals marked heterogeneity of the endoplasmic reticulum proteome in cancer (2008) |
|---|
| Authors | Shnyder S.;Mangum J.;Hubbard M. |
|---|
| Journal | Journal of Proteome Research |
|---|
| DOI | 10.1021/pr800126n |
|---|
| |
| Title | A cytotoxic diterpenoid from Croton membranaceus, the major constituent of anticancer herbal formulations in Ghana (2008) |
|---|
| Authors | Bayor, M.T.; Ayim, J.S.K.; Marston, G.; Phillips, Roger M.; Shnyder, Steven D.; Wheelhouse, Richard T.; Wright, Colin W. |
|---|
| |
| Title | Guaianolide sesquiterpenes from Pulicaria crispa (Forssk.) Oliv. (2008) |
|---|
| Authors | Stavri, M.; Matthew, K.T.; Gordon, Andrew; Shnyder, Steven D.; Falconer, Robert A.; Gibbons, S. |
|---|
| Journal | Phytochemistry |
|---|
| |
| Title | Auristatin PYE, a novel synthetic derivative of dolastatin 10, is highly effective in human colon tumour models. (2007) |
|---|
| Authors | Shnyder, Steven D.; Cooper, Patricia A.; Millington, Nicola J.; Pettit, G.R.; Bibby, Michael C. |
|---|
| |
| Title | Synthesis of cryptolepine analogues as potential bioreducible anticancer agents (2007) |
|---|
| Authors | Seville S.;Phillips R.;Shnyder S.;Wright C. |
|---|
| Journal | Bioorganic and Medicinal Chemistry |
|---|
| DOI | 10.1016/j.bmc.2007.06.062 |
|---|
| |
| Title | Synthesis of DNA-Directed Pyrrolidinyl and Piperidinyl Confined Alkylating Chloroalkylaminoanthraquinones: Potential for Development of Tumor-Selective N-Oxides (2006) |
|---|
| Authors | Patterson, Laurence H.; Pors, Klaus; Shnyder, Steven D.; Teesdale-Spittle, P.H.; Hartley, J.A.; Searcey, M.; Zloh, M. |
|---|
| |
| Title | Reducing the cost of screening novel agents using the hollow fibre assay (2006) |
|---|
| Authors | Shnyder S.;Cooper P.;Scally A.;Bibby M. |
|---|
| Journal | Anticancer Research |
|---|
| |
| Title | Design, synthesis, and biophysical and biological evaluation of a series of pyrrolobenzodiazepine-poly(N-methylpyrrole) conjugates (2006) |
|---|
| Authors | Wells G.;Martin C.;Howard P.;Sands Z.;Laughton C.;Tiberghien A.;Woo C.;Masterson L.;Stephenson M.;Hartley J.;Jenkins T.;Shnyder S.;Loadman P.;Waring M.;Thurston D. |
|---|
| Journal | Journal of Medicinal Chemistry |
|---|
| DOI | 10.1021/jm051199z |
|---|
| |
| Title | The hollow fibre model - Facilitating anti-cancer pre-clinical pharmacodynamics and improving animal welfare (2006) |
|---|
| Authors | Suggitt M.;Cooper P.;Shnyder S.;Bibby M. |
|---|
| Journal | International Journal of Oncology |
|---|
| |
| Title | Heparin octasaccharides inhibit angiogenesis in vivo. (2005) |
|---|
| Authors | Hasan, J.; Shnyder, Steven D.; Clamp, A.R.; McGown, A.T.; Bicknell, R.; Presta, M.; Bibby, Michael C.; Double, John A.; Craig, S.; Leeming, D.; Stevenson, K.; Gallagher, J.T.; Jayson, G.C. |
|---|
| |
| Title | Development of a modified hollow fibre assay for studying agents targeting the tumour neovasculature (2005) |
|---|
| Authors | Shnyder S.;Hasan J.;Cooper P.;Pilarinou E.;Jubb E.;Jayson G.;Bibby M. |
|---|
| Journal | Anticancer Research |
|---|
| |
| Title | Synthesis of some cryptolepine analogues, assessment of their antimalarial and cytotoxic activities, and consideration of their antimalarial mode of action. (2005) |
|---|
| Authors | Wright, Colin W.; Onyeibor, O.; Phillips, Roger M.; Shnyder, Steven D.; Croft, S.L.; Dodson, Hilary I. |
|---|
| |
| Title | Preliminary pharmacokinetic and bioanalytical studies of SJG-136 (NSC 694501), a sequence-selective pyrrolobenzodiazepine dimer DNA-cross-linking agent. (2004) |
|---|
| Authors | Wilkinson, Gary P.; Taylor, James P.; Shnyder, Steven D.; Loadman, Paul M.; Cooper, Patricia A.; Howard, P.W.; Thurston, D.E.; Jenkins, Terence C. |
|---|
| |
| Title | Secretory phospholipase A2 as a tumor specific trigger for targeted delivery of a novel class of liposomal prodrug anticancer etherlipids (2004) |
|---|
| Authors | Gill, Jason H.; Bibby, Michael C.; Jensen, S.S.; Shnyder, Steven D. |
|---|
| |
| Title | Vinflunine Pierre Fabre/Bristol-Myers Squibb (2004) |
|---|
| Authors | Shnyder S. |
|---|
| Journal | IDrugs : the investigational drugs journal |
|---|
| |
| Title | Comparative Preclinical Pharmacokinetic and Metabolic Studies of the Combretastatin Prodrugs Combretastatin A4 Phosphate and A1 Phosphate (2004) |
|---|
| Authors | Kirwan, Ian G.; Loadman, Paul M.; Swaine, David J.; Anthoney, Alan; Pettit, G.R.; Lippert III, J.W.; Shnyder, Steven D.; Cooper, Patricia A.; Bibby, Michael C. |
|---|
| |
| Title | Pharmacological and biological evaluation of a series of substituted 1,4 naphthoquinone bioreductive drugs. (2004) |
|---|
| Authors | Phillips, Roger M.; Loadman, Paul M.; Maitland, Derek J.; Shnyder, Steven D.; Jaffar, M.; Steans, Gillian; Cooper, Patricia A.; Race, Amanda D.; Patterson, A.V.; Stratford, I.J. |
|---|
| |
| Title | Secretory phospholipase A2as tumor-specific trigger for targeted delivery of a novel class of liposomal prodrug anticancer etherlipids (2004) |
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| Authors | Jensen S.;Andresen T.;Davidsen J.;Høyrup P.;Shnyder S.;Bibby M.;Gill J.;Jørgensen K. |
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| Journal | Molecular Cancer Therapeutics |
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| |
| Title | Combretastatin A-1 phosphate potentiates the antitumour activity of cisplatin in a murine adenocarcinoma model (2003) |
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| Authors | Shnyder S.;Cooper P.;Pettit G.;Lippert J.;Bibby M. |
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| Journal | Anticancer Research |
|---|
| |
| Title | Vinflunine Potentiates the Activity of Cisplatin but Not 5-Fluorouracil in A Transplantable Murine Adenocarcinoma Model (2003) |
|---|
| Authors | Shnyder S.;Cooper P.;Gyselinck N.;Hill B.;Double J.;Bibby M. |
|---|
| Journal | Anticancer Research |
|---|
| |
| Title | In vitro and in vivo activity of LS 4477 and LS 4559, novel analogues of the tubulin binder estramustine (2002) |
|---|
| Authors | Nicholson K.;Phillips R.;Shnyder S.;Bibby M. |
|---|
| Journal | European Journal of Cancer. Part A |
|---|
| DOI | 10.1016/S0959-8049(01)00341-0 |
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| |
| Title | Combretastatin A-1 phosphate a novel tubulin-binding agent with in vivo anti vascular effects in experimental tumours (2002) |
|---|
| Authors | Holwell S.;Cooper P.;Grosios K.;Lippert J.;Pettit G.;Shnyder S.;Bibby M. |
|---|
| Journal | Anticancer Research |
|---|
| |
