| Title | Targeted delivery of a colchicine analogue provides synergy with ATR inhibition in cancer cells. (2022) |
|---|
| Authors | Barnieh FM;Ribeiro Morais G;Garland H;Loadman PM;Falconer RA; |
|---|
| Journal | Biochemical Pharmacology |
|---|
| DOI | 10.1016/j.bcp.2022.115095 |
|---|
| |
| Title | The role of MT1-MMP in the progression and metastasis of osteosarcoma (2022) |
|---|
| Authors | Spencer, H.L.M.; Shnyder, S.D.; Loadman, P.M.; Falconer, R.A. |
|---|
| Journal | Journal of Cancer Metastasis and Treatment |
|---|
| DOI | DOI:10.20517/2394-4722.2021.174 |
|---|
| |
| Title | Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs. (2022) |
|---|
| Authors | Eschweiler S;Ramírez-Suástegui C;Li Y;King E;Chudley L;Thomas J;Wood O;von Witzleben A;Jeffrey D;McCann K;Simon H;Mondal M;Wang A;Dicker M;Lopez-Guadamillas E;Chou TF;Dobbs NA;Essame L;Acton G;Kelly F;Halbert G;Sacco JJ;Schache AG;Shaw R;McCaul JA;Paterson C;Davies JH;Brennan PA;Singh RP;Loadman PM;Wilson W;Hackshaw A;Seumois G;Okkenhaug K;Thomas GJ;Jones TM;Ay F;Friberg G;Kronenberg M;Vanhaesebroeck B;Vijayanand P;Ottensmeier CH; |
|---|
| Journal | Nature |
|---|
| DOI | 10.1038/s41586-022-04685-2 |
|---|
| |
| Title | Is tumour-expressed aminopeptidase N (APN/CD13) structurally and functionally unique? (2021) |
|---|
| Authors | Barnieh FM;Loadman PM;Falconer RA; |
|---|
| Journal | Biochimica et Biophysica Acta - Reviews on Cancer |
|---|
| DOI | 10.1016/j.bbcan.2021.188641 |
|---|
| |
| Title | Cytochrome P450 isoforms 1A1, 1B1 AND 2W1 as targets for therapeutic intervention in head and neck cancer. (2021) |
|---|
| Authors | Presa D;Khurram SA;Zubir AZA;Smarakan S;Cooper PA;Morais GR;Sadiq M;Sutherland M;Loadman PM;McCaul J;Shnyder SD;Patterson LH;Pors K; |
|---|
| Journal | Scientific Reports |
|---|
| DOI | 10.1038/s41598-021-98217-z |
|---|
| |
| Title | Probing cytochrome P450 (CYP) bioactivation with chloromethylindoline bioprecursors derived from the duocarmycin family of compounds. (2021) |
|---|
| Authors | Ortuzar N;Karu K;Presa D;Morais GR;Sheldrake HM;Shnyder SD;Barnieh FM;Loadman PM;Patterson LH;Pors K;Searcey M; |
|---|
| Journal | Bioorganic and Medicinal Chemistry |
|---|
| DOI | 10.1016/j.bmc.2021.116167 |
|---|
| |
| Title | How can the potential of the duocarmycins be unlocked for cancer therapy? (2021) |
|---|
| Authors | Jukes Z;Morais GR;Loadman PM;Pors K; |
|---|
| Journal | Drug Discovery Today |
|---|
| DOI | 10.1016/j.drudis.2020.11.020 |
|---|
| |
| Title | Cytochrome P450 Binding and Bioactivation of Tumor-targeted Duocarmycin Agents. (2021) |
|---|
| Authors | Bart AG;Morais G;Vangala VR;Loadman PM;Pors K;Scott EE; |
|---|
| Journal | Drug Metabolism And Disposition: The Biological Fate Of Chemicals |
|---|
| DOI | 10.1124/dmd.121.000642 |
|---|
| |
| Title | Luminal bioavailability in the distal small intestine and changes to the ileal microbiome after oral administration of omega-3 polyunsaturated fatty acids (2021) |
|---|
| Authors | Gael Nana, Henry Watson, Suparna Mitra, Caroline Young, Henry M Wood, Sarah L Perry, Amanda D Race, Philip Quirke, Giles J Toogood, Paul M Loadman, Mark A Hull |
|---|
| Journal | Journal of Nutrition |
|---|
| DOI | doi: 10.1093/jn/nxab113 |
|---|
| |
| Title | Targeted microbubbles carrying lipid-oil-nanodroplets for ultrasound-triggered delivery of the hydrophobic drug, Combretastatin A4. (2021) |
|---|
| Authors | Charalambous A;Mico V;McVeigh LE;Marston G;Ingram N;Volpato M;Peyman SA;McLaughlan JR;Wierzbicki A;Loadman P;Bushby RJ;Markham AF;Evans SD;Coletta PL; |
|---|
| Journal | Nanomedicine: Nanotechnology, Biology, and Medicine |
|---|
| DOI | 10.1016/j.nano.2021.102401 |
|---|
| |
| Title | Progress towards a clinically-successful ATR inhibitor for cancer therapy (2021) |
|---|
| Authors | Barnieh, F.M.; Loadman, P.M.; Falconer, R.A. |
|---|
| Journal | Current Research in Pharmacology and Drug Discovery |
|---|
| DOI | 10.1016/j.crphar.2021.100017 |
|---|
| |
| Title | An assay for quantitative analysis of polysialic acid expression in cancer cells (2021) |
|---|
| Authors | Guo, X.; Elkashef, S.M.; Patel, A.; Ribeiro Morais, G.; Shnyder S.D.; Loadman, P.M.; Patterson, L.H.; Falconer, R.A. |
|---|
| Journal | Carbohydrate Polymers |
|---|
| DOI | 10.1016/j.carbpol.2021.117741 |
|---|
| |
| Title | An efficient assay for identification and quantitative evaluation of potential polysialyltransferase inhibitors. (2020) |
|---|
| Authors | Guo X; Malcolm J.R.; Ali M.M.; Ribeiro Morais G; Shnyder S.D.; Loadman P.M.; Patterson L.H.; Falconer R.A. |
|---|
| Journal | ANALYST (PRINT) |
|---|
| DOI | 10.1039/d0an00721h |
|---|
| |
| Title | Ultrasound-triggered therapeutic microbubbles enhance the efficacy of cytotoxic drugs by increasing circulation and tumour drug accumulation and limiting bioavailability and toxicity in normal tissues (2020) |
|---|
| Authors | Nicola Ingram1*, Laura E. McVeigh1*, Radwa H. Abou-Saleh2,3, Juliana Maynard4, Sally A. Peyman2, James R. McLaughlan5, Michael Fairclough6, Gemma Marston1, Elizabeth M.A. Valleley 1, Jorge L. Jimenez-Macias1, Antonia Charalambous1, William Townley4, Malcolm Haddrick4, Antonia Wierzbicki7, Alexander Wright1, Milène Volpato1, Peter B. Simpson4, Darren E. Treanor1, Neil H. Thomson8, Paul M. Loadman7, Richard J. Bushby2,9, Benjamin R.G. Johnson2, Pamela F. Jones1, Tony Evans1, Steven Freear5, Alexander F. Markham1, Stephen D. Evans2,*, P. Louise Coletta1,* |
|---|
| Journal | Theranostics |
|---|
| Publisher | Ivy Spring |
|---|
| DOI | DOI: 10.7150/thno.49670 |
|---|
| |
| Title | Inactivation of apaziquone by haematuria: implications for the design of phase III clinical trials against non-muscle invasive bladder cancer (2019) |
|---|
| Authors | Roger M. Phillips, Paul M. Loadman, Guru Reddy |
|---|
| Journal | Cancer Chemotherapy and Pharmacology |
|---|
| DOI | 10.1007/s00280-019-03812-7 |
|---|
| |
| Title | Precision pharmacology: Mass spectrometry imaging and pharmacokinetic drug resistance (2019) |
|---|
| Authors | Jove, M.; Spencer, Jade A.; Clench, M.; Loadman, Paul M.; Twelves, C. |
|---|
| Journal | Critical Reviews in Oncology/Hematology |
|---|
| DOI | DOI.org/10.1016/j.critrevonc.2019.06.008 |
|---|
| |
| Title | Theranostic nanoparticles enhance the response of glioblastomas to radiation (2019) |
|---|
| Authors | Wu, W.; Klockow, J.L.; Mohanty, S.; Ku, K.S.; Aghighi, M.; Melemenidis, S.; Chen, Z.; Li, K.; Ribeiro Morais, Goreti; Zhao, N.; Schlegel, J.; Graves, E.E.; Rao, J.; Loadman, Paul M.; Falconer, R.A.; Mukherjee, S.; Chin, F.T.; Daldrup-Link, H.E. |
|---|
| Journal | Nanotheranostics |
|---|
| DOI | 10.7150/ntno.35342 |
|---|
| |
| Title | Cellular uptake and efflux of palbociclib in vitro in single cell and spheroid models. (2019) |
|---|
| Authors | Jove M;Spencer JA;Hubbard ME;Holden EC;O'Dea RD;Brook BS;Phillips RM;Smye SW;Loadman P;Twelves CJ; |
|---|
| Journal | Journal of Pharmacology and Experimental Therapeutics |
|---|
| DOI | 10.1124/jpet.119.256693 |
|---|
| |
| Title | Recent advances in the analysis of polysialic acid from complex biological systems (2019) |
|---|
| Authors | Xiaoxiao Guo, Sara M. Elkashef, Mark Sutherland, Paul M. Loadman and Robert A. Falconer |
|---|
| Journal | Carbohydrate Polymers |
|---|
| DOI | 10.1016/j.carbpol.2019.115145 |
|---|
| |
| Title | Precision pharmacology: Mass spectrometry imaging and pharmacokinetic drug resistance (2019) |
|---|
| Authors | Jove, M.; Spencer, Jade A.; Clench, M.; Loadman, Paul M.; Twelves, C. |
|---|
| Journal | Critical Reviews in Oncology/Hematology |
|---|
| DOI | DOI.org/10.1016/j.critrevonc.2019.06.008 |
|---|
| |
| Title | Structural properties governing drug-plasma protein binding determined by high-performance liquid chromatography method (2018) |
|---|
| Authors | Kamble, Sharad R.; Loadman, Paul M.; Abraham, M.H.; Liu, Xiangli |
|---|
| Journal | Journal of Pharmaceutical and Biomedical Analysis |
|---|
| DOI | doi.org/10.1016/j.jpba.2017.10.022 |
|---|
| |
| Title | A randomised trial of the effect of omega-3 polyunsaturated fatty acid supplements on the human intestinal microbiota (2018) |
|---|
| Authors | Watson, H.; Mitra, S.; Croden, F.C.; Taylor, M.; Wood, H.M.; Perry, S.L.; Spencer, Jade A.; Quirke, P.; Toogood, G.J.; Lawton, C.L.; Dye, L.; Loadman, Paul M.; Hull, M.A. |
|---|
| Journal | Gut |
|---|
| DOI | doi: 10.1136/gutjnl-2017-314968 |
|---|
| |
| Title | A study of inter-individual variability in the Phase II metabolism of xenobiotics in human skin (2018) |
|---|
| Authors | Spriggs, S.; Cubberley, R.; Loadman, Paul M.; Sheffield, D.; Wierzbicki, Antonia |
|---|
| Journal | Toxicology Letters |
|---|
| DOI | doi.org/10.1016/j.toxlet.2018.04.011 |
|---|
| |
| Title | Eicosapentaenoic acid and aspirin, alone and in combination, for the prevention of colorectal adenomas (seAFOod Polyp Prevention trial): a multicentre, randomised, double-blind, placebo-controlled, 2 × 2 factorial trial (2018) |
|---|
| Authors | Hull, M.A.; Sprange, K.; Hepburn, T.; Tan, W.; Shafayat, A.; Rees, C.J.; Clifford, G.; Logan, R.F.; Loadman, Paul M.; Williams, E.A.; Whitham, D.; Montgomery, A.A. |
|---|
| Journal | Lancet |
|---|
| DOI | doi.org/10.1016/S0140-6736(18)31775-6 |
|---|
| |
| Title | A liquid chromatography-tandem mass spectrometry method to measure fatty acids in biological samples (2017) |
|---|
| Authors | Volpato, Milène; Spencer, Jade A.; Race, Amanda D.; Munarini, A.; Belluzzi, A.; Cockbain, A.; Hull, M.; Loadman, Paul M. |
|---|
| Journal | J Chromatography B |
|---|
| DOI | doi.org/10.1016/j.jchromb.2017.04.030 |
|---|
| |
| Title | A novel theranostic strategy for MMP-14 expressing glioblastomas impacts survival (2017) |
|---|
| Authors | Mohanty, S.; Chen, Z.; Li, K.; Ribeiro Morais, G.; Klockow, J.; Yerneni, K.; Pasani, L.; Chin, F.T.; Mitra, S.; Cheshier, S.; Chang, E.; Gambhir, S.S.; Rao, J.; Loadman, P.M.; Falconer, R.A.; Daldrup-Link, H.E. |
|---|
| Journal | Molecular Cancer Therapeutics |
|---|
| DOI | 10.1158/1535-7163.MCT-17-0022 |
|---|
| |
| Title | Drug delivery in a tumour cord model: a computational simulation (2017) |
|---|
| Authors | Hubbard, M.E.; Jove, M.; Loadman, Paul M.; Phillips, Roger M.; Twelves, Christopher J.; Smye, S.W. |
|---|
| Journal | Royal Society Open Science |
|---|
| DOI | doi.org/10.1098/rsos.170014 |
|---|
| |
| Title | Membrane-type matrix metalloproteinases: expression, roles in metastatic prostate cancer progression and opportunities for drug targeting (2017) |
|---|
| Authors | Falconer, R.A.; Loadman, P.M. |
|---|
| Journal | Journal of Cancer Metastasis and Treatment |
|---|
| DOI | 10.20517/2394-4722.2017.40 |
|---|
| |
| Title | Rationalized Computer-Aided Design of Matrix-Metalloprotease-Selective Prodrugs (2017) |
|---|
| Authors | Jain, M.; Harburn, J.J.; Gill, J.H.; Loadman, P.M.; Falconer, R.A.; Mooney, C.A.; Cobb, S.L.; Berry, David J. |
|---|
| Journal | Journal of Medicinal Chemistry |
|---|
| DOI | 10.1021/acs.jmedchem.6b01472 |
|---|
| |
| Title | Polysialic acid sustains cancer cell survival and migratory capacity in a hypoxic environment (2016) |
|---|
| Authors | Elkashef, Sara M.; Allison, Simon J.; Sadiq, Maria; Basheer, Haneen A.; Ribeiro Morais, Goreti; Loadman, Paul M.; Pors, Klaus; Falconer, Robert A. |
|---|
| Journal | Scientific Reports |
|---|
| DOI | 10.1038/srep33026 |
|---|
| |
| Title | Proteases in cancer drug delivery (2016) |
|---|
| Authors | Vandooren, J.; Opdenakker, G.; Loadman, Paul M.; Edwards, D.R. |
|---|
| Journal | Advanced Drug Delivery Reviews |
|---|
| DOI | dx.doi.org/10.1016/j.addr.2015.12.020 |
|---|
| |
| Title | An optimised assay for quantitative, high-throughput analysis of polysialyltransferase activity (2016) |
|---|
| Authors | Elkashef, Sara M.; Sutherland, Mark H.; Patterson, Laurence H.; Loadman, Paul M.; Falconer, Robert A. |
|---|
| Journal | ANALYST (PRINT) |
|---|
| DOI | 10.1039/c6an01073c |
|---|
| |
| Title | Measurement of red blood cell eicosapentaenoic acid (EPA) levels in a randomised trial of EPA in patients with colorectal cancer liver metastases (2016) |
|---|
| Authors | Watson, H.; Cockbain, A.J.; Spencer, Jade A.; Race, Amanda D.; Volpato, Milène; Loadman, Paul M.; Toogood, G.J.; Hull, M.A. |
|---|
| Journal | Prostaglandins Leukotrienes and Essential Fatty Acids |
|---|
| DOI | dx.doi.org/10.1016/j.plefa.2016.10.003 |
|---|
| |
| Title | Probing cytochrome P450-mediated activation with a truncated azinomycin analogue (2015) |
|---|
| Authors | Vinader, Victoria; Sadiq, Maria; Sutherland, Mark H.; Huang, M.Y.; Loadman, Paul M.; Elsalem, Lina M.I.; Shnyder, Steven D.; Cui, H.J.; Afarinkia, Kamyar; Searcey, M.; Patterson, Laurence H.; Pors, Klaus |
|---|
| Journal | MedChemComm |
|---|
| DOI | dx.doi.org/10.1039/c4md00411f |
|---|
| |
| Title | Thin-layer chromatography/matrix-assisted laser desorption/ionisation mass spectrometry and matrix-assisted laser desorption/ionisation mass spectrometry imaging for the analysis of phospholipids in LS174T colorectal adenocarcinoma xenografts treated with the vascular disrupting agent DMXAA (2015) |
|---|
| Authors | Batubara, A.; Carolan, V.A.; Loadman, Paul M.; Sutton, Chris W.; Shnyder, Steven D.; Clench, M.R. |
|---|
| Journal | Rapid Communications In Mass Spectrometry |
|---|
| DOI | doi.org/10.1002/rcm.7223 |
|---|
| |
| Title | Mathematical and computational models of drug transport in tumours (2014) |
|---|
| Authors | Groh, C.M.; Hubbard, M.E.; Jones, P.F.; Loadman, Paul M.; Periasamy, Nagarajan; Sleeman, B.D.; Smye, S.W.; Twelves, Christopher J.; Phillips, Roger M. |
|---|
| Journal | Journal of the Royal Society Interface |
|---|
| DOI | doi.org/10.1098/rsif.2013.1173 |
|---|
| |
| Title | Development of Novel Tumor-Targeted Theranostic Nanoparticles Activated by Membrane-Type Matrix Metalloproteinases for Combined Cancer Magnetic Resonance Imaging and Therapy (2014) |
|---|
| Authors | Ansari, C.; Tikhomirov, G.A.; Hong, S.H.; Falconer, Robert A.; Loadman, Paul M.; Gill, Jason H.; Castaneda, R.; Hazard, F.K.; Tong, L.; Lenkov, O.D.; Felsher, D.W.; Rao, J.; Daldrup-Link, H.E. |
|---|
| Journal | Small |
|---|
| DOI | 10.1002/smll.201301456 |
|---|
| |
| Title | In vitro 3D colon tumor penetrability of SRJ09, a new anti-cancer andrographolide analog (2014) |
|---|
| Authors | Wong, C.C.; Periasamy, Nagarajan; Sagineedu, S.R.; Sidik, S.; Sumon, S.H.; Loadman, Paul M.; Phillips, Roger M.; Lajis, N.H.; Stanslas, J. |
|---|
| Journal | Investigational New Drugs |
|---|
| DOI | doi.org/10.1007/s10637-014-0105-6 |
|---|
| |
| Title | Mucosal biomarkers of colorectal cancer risk do not increase at 6 months following sleeve gastrectomy, unlike gastric bypass (2014) |
|---|
| Authors | Kant, P.; Perry, S.L.; Dexter, S.P.; Race, Amanda D.; Loadman, Paul M. |
|---|
| Journal | Bmc Obesity |
|---|
| DOI | doi.org/10.1002/oby.20493 |
|---|
| |
| Title | Anticolorectal cancer activity of the omega-3 polyunsaturated fatty acid eicosapentaenoic acid (2014) |
|---|
| Authors | Cockbain, A.J.; Volpato, Milène; Race, Amanda D.; Munarini, A.; Fazio, C.; Belluzzi, A.; Loadman, Paul M.; Toogood, G.J.; Hull, M.A. |
|---|
| Journal | Gut |
|---|
| DOI | doi.org/10.1136/gutjnl-2013-306445 |
|---|
| |
| Title | Eicosapentaenoic acid free fatty acid prevents and suppresses colonic neoplasia in colitis-associated colorectal cancer acting on Notch signaling and gut microbiota (2014) |
|---|
| Authors | Piazzi, G.; D'Argenio, G.; Prossomariti, A.; Lembo, V.; Mazzone, G.; Candela, M.; Biagi, E.; Brigidi, P.; Vitaglione, P.; Fogliano, V.; D'Angelo, L.; Fazio, C.; Munarini, A.; Belluzzi, A.; Ceccarelli, C.; Chieco, P.; Balbi, T.; Loadman, Paul M.; Hull, M.A.; Romano, M.; Bazzoli, F.; Ricciardiello, L. |
|---|
| Journal | International Journal of Cancer |
|---|
| DOI | doi.org/10.1002/ijc.28853 |
|---|
| |
| Title | Tumor-Targeted Prodrug ICT2588 Demonstrates Therapeutic Activity Against Solid Tumors and Reduced Potential For Cardiovascular Toxicity (2014) |
|---|
| Authors | Gill, Jason H.; Loadman, Paul M.; Shnyder, Steven D.; Cooper, Patricia A.; Atkinson, Jennifer M.; Ribeiro Morais, Goreti; Patterson, Laurence H.; Falconer, Robert A. |
|---|
| Journal | Molecular Cancer Therapeutics |
|---|
| DOI | 10.1021/mp400760b |
|---|
| |
| Title | A randomized controlled trial of eicosapentaenoic acid and/or aspirin for colorectal adenoma prevention during colonoscopic surveillance in the NHS Bowel Cancer Screening Programme (The seAFOod Polyp Prevention Trial): Study protocol for a randomized controlled trial (2013) |
|---|
| Authors | Hull M.;Sandell A.;Montgomery A.;Logan R.;Clifford G.;Rees C.;Loadman P.;Whitham D. |
|---|
| Journal | Trials |
|---|
| DOI | 10.1186/1745-6215-14-237 |
|---|
| |
| Title | Pharmacological Inhibition of polysialyltransferase ST8SiaII Modulates Tumour Cell Migration (2013) |
|---|
| Authors | Al-Saraireh, Yousef M.J.; Sutherland, Mark H.; Springett, Bradley R.; Freiberger, F.; Ribeiro Morais, Goreti; Loadman, Paul M.; Errington, R.J.; Smith, P.J.; Fukuda, M.; Gerardy-Schahn, R.; Patterson, Laurence H.; Shnyder, Steven D.; Falconer, Robert A. |
|---|
| Journal | PLoS ONE |
|---|
| DOI | 10.1371/journal.pone.0073366 |
|---|
| |
| Title | Antitumor activity of a duocarmycin analogue rationalized to be metabolically activated by cytochrome P450 1A1 in human transitional cell carcinoma of the bladder (2013) |
|---|
| Authors | Sutherland, Mark H.; Gill, Jason H.; Loadman, Paul M.; Laye, Jonathan P.; Sheldrake, Helen M.; Illingworth, Nicola A.; Alandas, Mohammed N.; Cooper, Patricia A.; Searcey, M.; Pors, Klaus; Shnyder, Steven D.; Patterson, Laurence H. |
|---|
| |
| Title | Re-engineering of the Duocarmycin Structural Architecture Enables Bioprecursor Development Targeting CYP1A1 and CYP2W1 for Biological Activity (2013) |
|---|
| Authors | Sheldrake, Helen M.; Travica, S.; Johansson, I.; Loadman, Paul M.; Sutherland, Mark H.; Elsalem, Lina M.I.; Illingworth, Nicola A.; Cresswell, Alexander J.; Reuillon, Tristan; Shnyder, Steven D.; Mkrtchian, S.; Searcey, M.; Ingelman-Sundberg, M.; Patterson, Laurence H.; Pors, Klaus |
|---|
| |
| Title | Targeting of Hypoxia in AQ4N-treated Tumour Xenografts by MALDI-Ion Mobility Separation-Mass Spectrometry Imaging (2013) |
|---|
| Authors | Djidja, M-C.; Francese, S.; Claude, E.; Loadman, Paul M.; Sutton, Chris W.; Shnyder, Steven D.; Cooper, Patricia A.; Patterson, Laurence H.; Carolan, V.A.; Clench, M.R. |
|---|
| |
| Title | A randomised controlled trial of eicosapentaenoic acid and/or aspirin for colorectal adenoma (or polyp) prevention during colonoscopic surveillance in the NHS Bowel Cancer Screening Programme: The seAFOod (Systematic Evaluation of Aspirin and Fish Oil) Polyp Prevention Trial (2013) |
|---|
| Authors | Hull, M.A.; Sandell, A.C.; Montgomery, A.A.; Logan, R.F.A.; Clifford, G.M.; Rees, C.J.; Loadman, Paul M.; Whitham, D. |
|---|
| |
| Title | Identification of Stage-Specific Breast Markers using Quantitative Proteomics (2013) |
|---|
| Authors | Shaheed, Sadr-ul; Rustogi, Nitin; Scally, Andy J.; Wilson, J.; Thygesen, H.; Loizidou, M.A.; Hadjisavvas, A.; Hanby, A.; Speirs, V.; Loadman, Paul M.; Linforth, R.; Kyriacou, K.; Sutton, Chris W. |
|---|
| |
| Title | Colon cancer-specific cytochrome P450 2W1 converts duocarmycin analogues into potent tumor cytotoxins (2013) |
|---|
| Authors | Travica, S.; Pors, Klaus; Loadman, Paul M.; Shnyder, Steven D.; Johansson, I.; Alandas, Mohammed N.; Sheldrake, Helen M.; Mkrtchian, S.; Patterson, Laurence H.; Ingelman-Sundberg, M. |
|---|
| |
| Title | FGFR1-induced Epithelial to mesenchymal transition through MAPK/PLCγ/COX-2-mediated mechanisms (2012) |
|---|
| Authors | Tomlinson D.;Baxter E.;Loadman P.;Hull M.;Knowles M. |
|---|
| Journal | PLoS ONE |
|---|
| DOI | 10.1371/journal.pone.0038972 |
|---|
| |
| Title | Synthesis and biological evaluation of colchicine B-ring analogues tethered with halogenated benzyl moieties (2012) |
|---|
| Authors | Cosentino L.;Redondo-Horcajo M.;Zhao Y.;Santos A.;Chowdury K.;Vinader V.;Abdallah Q.;Abdel-Rahman H.;Fournier-Dit-Chabert J.;Shnyder S.;Loadman P.;Fang W.;Díaz J.;Barasoain I.;Burns P.;Pors K. |
|---|
| Journal | Journal of Medicinal Chemistry |
|---|
| DOI | 10.1021/jm301151t |
|---|
| |
| Title | Synthesis and biological evaluation of colchicine C-ring analogues tethered with aliphatic linkers suitable for prodrug derivatisation (2012) |
|---|
| Authors | Fournier-Dit-Chabert J.;Vinader V.;Santos A.;Redondo-Horcajo M.;Dreneau A.;Basak R.;Cosentino L.;Marston G.;Abdel-Rahman H.;Loadman P.;Shnyder S.;Díaz J.;Barasoain I.;Falconer R.;Pors K. |
|---|
| Journal | Bioorganic and Medicinal Chemistry Letters |
|---|
| DOI | 10.1016/j.bmcl.2012.09.104 |
|---|
| |
| Title | The omega-3 polyunsaturated fatty acid eicosapentaenoic acid inhibits mouse MC-26 colorectal cancer cell liver metastasis via inhibition of PGE2-dependent cell motility (2012) |
|---|
| Authors | Hawcroft G.;Volpato M.;Marston G.;Ingram N.;Perry S.;Cockbain A.;Race A.;Munarini A.;Belluzzi A.;Loadman P.;Coletta P.;Hull M. |
|---|
| Journal | British Journal of Pharmacology |
|---|
| DOI | 10.1111/j.1476-5381.2012.01882.x |
|---|
| |
| Title | Anti-colorectal cancer activity of an organometallic osmium arene azopyridine complex (2011) |
|---|
| Authors | Shnyder S.;Fu Y.;Habtemariam A.;Van Rijt S.;Cooper P.;Loadman P.;Sadler P. |
|---|
| Journal | MedChemComm |
|---|
| DOI | 10.1039/c1md00075f |
|---|
| |
| Title | Total synthesis of largazole and analogues: HDAC inhibition, antiproliferative activity and metabolic stability (2011) |
|---|
| Authors | Benelkebir H.;Marie S.;Hayden A.;Lyle J.;Loadman P.;Crabb S.;Packham G.;Ganesan A. |
|---|
| Journal | Bioorganic and Medicinal Chemistry |
|---|
| DOI | 10.1016/j.bmc.2011.02.024 |
|---|
| |
| Title | Modification of the duocarmycin pharmacophore enables CYP1A1 targeting for biological activity (2011) |
|---|
| Authors | Pors, Klaus; Loadman, Paul M.; Shnyder, Steven D.; Sutherland, Mark H.; Sheldrake, Helen M.; Guino, M.; Kiakos, K.; Hartley, J.A.; Searcey, M.; Patterson, Laurence H. |
|---|
| |
| Title | Chromatographie analysis of polysialic acid released from neural adhesion molecule presented on glioma cell membranes (2011) |
|---|
| Authors | Al-Hasawi N.;Volapato M.;Loadman P. |
|---|
| Journal | Kuwait Journal of Science and Engineering |
|---|
| |
| Title | Effect of eicosapentaenoic acid on E-type prostaglandin synthesis and EP4 receptor signaling in human colorectal cancer cells (2010) |
|---|
| Authors | Hawcroft G.;Loadman P.;Belluzzi A.;Hull M. |
|---|
| Journal | Neoplasia |
|---|
| DOI | 10.1593/neo.10388 |
|---|
| |
| Title | Development of a novel tumor-targeted vascular disrupting agent activated by membrane-type matrix metalloproteinases (2010) |
|---|
| Authors | Atkinson J.;Falconer R.;Edwards D.;Pennington C.;Siller C.;Shnyder S.;Bibby M.;Patterson L.;Loadman P.;Gill J. |
|---|
| Journal | Cancer Research |
|---|
| DOI | 10.1158/0008-5472.CAN-10-1440 |
|---|
| |
| Title | Effect of eicosapentaenoic acid on E-type prostaglandin synthesis and EP4 receptor signalling in human colorectal cancer cells (2010) |
|---|
| Authors | Hawcroft, G.; Loadman, Paul M.; Belluzzi, A.; Hull, M.A. |
|---|
| |
| Title | Development of a novel tumor-targeted vascular disrupting agent activated by Membrane-type Matrix Metalloproteinases (MT-MMPs) (2010) |
|---|
| Authors | Atkinson, Jennifer M.; Falconer, Robert A.; Edwards, D.R.; Pennington, C.J.; Siller, Catherine S.; Shnyder, Steven D.; Bibby, Michael C.; Patterson, Laurence H.; Loadman, Paul M.; Gill, Jason H. |
|---|
| |
| Title | Evaluation of the safety of C-1311 (SYMADEX) administered in a phase 1 dose escalation trial as a weekly infusion for 3 consecutive weeks in patients with advanced solid tumours. (2010) |
|---|
| Authors | Isambert, N.; Campone, M.; Bourbouloux, E.; Drouin, M.; Major, A.; Yin, W.; Loadman, Paul M.; Capizzi, R.; Grieshaber, C.; Fumoleau, P. |
|---|
| |
| Title | In vivo activation of the hypoxia-targeted cytotoxin AQ4N in human tumor xenografts (2009) |
|---|
| Authors | Williams K.;Albertella M.;Fitzpatrick B.;Loadman P.;Shnyder S.;Chinje E.;Telfer B.;Dunk C.;Harris P.;Stratford I. |
|---|
| Journal | Molecular Cancer Therapeutics |
|---|
| DOI | 10.1158/1535-7163.MCT-09-0396 |
|---|
| |
| Title | Detergent addition to tryptic digests and ion mobility separation prior to MS/MS improves peptide yield and protein identification for in situ proteomic investigation of frozen and formalin-fixed paraffin-embedded adenocarcinoma tissue sections (2009) |
|---|
| Authors | Djidja M.;Francese S.;Loadman P.;Sutton C.;Scriven P.;Claude E.;Snel M.;Franck J.;Salzet M.;Clench M. |
|---|
| Journal | Proteomics |
|---|
| DOI | 10.1002/pmic.200800624 |
|---|
| |
| Title | The use of pharmacokinetic and pharmacodynamic end points to determine the dose of AQ4N, a novel hypoxic cell cytotoxin, given with fractionated radiotherapy in a phase I study. (2009) |
|---|
| Authors | Steward, W.P.; Middleton, M.; Benghiat, A.; Loadman, Paul M.; Hayward, C.; Walter, S.; Ford, S.; Halbert, G.; Patterson, Laurence H.; Talbot, D. |
|---|
| |
| Title | Phase I study of sequence-selective minor groove DNA binding agent SJG-136 in patients with advanced solid tumors (2009) |
|---|
| Authors | Hochhauser, D.; Meyer, T.; Spanswick, V.J.; Wu, J.; Clingen, P.H.; Loadman, Paul M.; Cobb, M.; Gumbrell, L.; Begent, R.H.; Hartley, J.A.; Jodrell, D. |
|---|
| |
| Title | Detergent addition to trypsin digest and Ion Mobility Separation prior to MS/MS improves peptide yield and Protein Identification for in situ Proteomic Investigation of Frozen and FFPE Adenocarcinoma tissue sections. (2009) |
|---|
| Authors | Djidja, M-C.; Francese, S.; Loadman, Paul M.; Sutton, Chris W.; Scriven, P.; Claude, E.; Snel, M.F.; Franck, J.; Salzet, M.; Clench, M.R. |
|---|
| |
| Title | In vivo activation of the hypoxia-targeted cytotoxin AQ4N in human tumor xenograft. (2009) |
|---|
| Authors | Williams, K.J.; Albertella, M.R.; Fitzpatrick, B.; Loadman, Paul M.; Shnyder, Steven D.; Chinje, E.C.; Telfer, B.A.; Dunk, C.R.; Harris, P.A.; Stratford, I.J. |
|---|
| |
| Title | A mathematical model of doxorubicin penetration through multicellular layers, (2009) |
|---|
| Authors | Evans, C.J.; Phillips, Roger M.; Jones, P.F.; Loadman, Paul M.; Sleeman, B.D.; Twelves, Christopher J.; Smye, S.W. |
|---|
| |
| Title | Hypoxia-selective targeting by the bioreductive prodrug AQ4N in patients with solid tumors: Results of a phase I study (2008) |
|---|
| Authors | Albertella M.;Loadman P.;Jones P.;Phillips R.;Rampling R.;Burnet N.;Alcock C.;Anthoney A.;Vjaters E.;Dunk C.;Harris P.;Wong A.;Lalani A.;Twelves C. |
|---|
| Journal | Clinical Cancer Research |
|---|
| DOI | 10.1158/1078-0432.CCR-07-4020 |
|---|
| |
| Title | Hypoxia-selective targeting by the bioreductive prodrug AQ4N in patients with solid tumors: results of a phase 1 study (2008) |
|---|
| Authors | Albertella, M.R.; Loadman, Paul M.; Jones, P.H.; Phillips, Roger M.; Rampling, R.; Burnet, N.; Alcock, C.; Anthoney, Alan; Vjaters, E.; Dunk, C.R.; Harris, P.A.; Wong, A.; Lalani, A.S.; Twelves, Christopher J. |
|---|
| |
| Title | Method development for protein profiling in biological tissues by matrix-assisted laser desorption/ionisation mass spectrometry imaging. (2008) |
|---|
| Authors | Djidja, M-C.; Carolan, V.A.; Loadman, Paul M.; Clench, M.R. |
|---|
| |
| Title | Fluorescent 7-Diethylaminocoumarin Pyrrolobenzodiazepine conjugates: Synthesis, DNA-Interaction, Cytotoxicity and Differential Cellular Localization. (2008) |
|---|
| Authors | Wells, G.; Suggitt, Marie; Coffils, M.; Baig, M.A.H.; Howard, P.W.; Loadman, Paul M.; Hartley, J.A.; Jenkins, Terence C.; Thurston, D.E. |
|---|
| |
| Title | The use of pharmacokinetic and pharmacodynamic end points to determine the dose of AQ4N, a novel hypoxic cell cytotoxin, given with fractionated radiotherapy in a phase I study (2007) |
|---|
| Authors | Steward W.;Middleton M.;Benghiat A.;Loadman P.;Hayward C.;Waller S.;Ford S.;Halbert G.;Patterson L.;Talbot D. |
|---|
| Journal | Annals of Oncology |
|---|
| DOI | 10.1093/annonc/mdm120 |
|---|
| |
| Title | Membrane type matrix metalloproteinases (MMPs) show differential expression in non-small cell lung cancer (NSCLC) compared to normal lung: Correlation of MMP-14 mRNA expression and proteolytic activity (2007) |
|---|
| Authors | Atkinson J.;Pennington C.;Martin S.;Anikin V.;Mearns A.;Loadman P.;Edwards D.;Gill J. |
|---|
| Journal | European Journal of Cancer. Part A |
|---|
| DOI | 10.1016/j.ejca.2007.05.009 |
|---|
| |
| Title | Chemical synthesis and biological evaluation of a NAD(P)H:quinone oxidoreductase-1-targeted tripartite quinone drug delivery system (2007) |
|---|
| Authors | Volpato, Milène; Abou-Zeid, N.; Tanner, R.W.; Glassbrook, L.T.; Taylor, James P.; Stratford, I.J.; Loadman, Paul M.; Jaffar, M.; Phillips, Roger M. |
|---|
| |
| Title | Membrane Type MMPs Show Differential Expression in Non-Small Cell Lung Cancer (NSCLC) Compared to Normal Lung; Correlation of MMP-14 mRNA Expression and Proteolytic Activity. (2007) |
|---|
| Authors | Atkinson, Jennifer M.; Gill, Jason H.; Loadman, Paul M.; Martin, Sandie W.; Pennington, J.; Anikin, V.A.; Mearns, A.J.; Edwards, D.R. |
|---|
| |
| Title | Preclinical pharmacology of the pyrrolobenzodiazepine (PBD) monomer DRH-417 (NSC 709119). (2007) |
|---|
| Authors | Burger, A.M.; Loadman, Paul M.; Thurston, D.E.; Schultz, R.; Fiebig, H.H.; Bibby, Michael C. |
|---|
| |
| Title | Examination of the distribution of the bioreductive drug AQ4N and its active metabolite AQ4 in solid tumours by imaging matrix-assisted laser desorption/ionisation mass spectrometry (2007) |
|---|
| Authors | Atkinson S.;Loadman P.;Sutton C.;Patterson L.;Clench M. |
|---|
| Journal | Rapid Communications In Mass Spectrometry |
|---|
| DOI | 10.1002/rcm.2952 |
|---|
| |
| Title | Design, synthesis, and biophysical and biological evaluation of a series of pyrrolobenzodiazepine-poly(N-methylpyrrole) conjugates (2006) |
|---|
| Authors | Wells G.;Martin C.;Howard P.;Sands Z.;Laughton C.;Tiberghien A.;Woo C.;Masterson L.;Stephenson M.;Hartley J.;Jenkins T.;Shnyder S.;Loadman P.;Waring M.;Thurston D. |
|---|
| Journal | Journal of Medicinal Chemistry |
|---|
| DOI | 10.1021/jm051199z |
|---|
| |
| Title | Phase I/II Pilot Study of Intravesical Apaziquone (EO9) for Superficial Bladder Cancer (2006) |
|---|
| Authors | Puri, Rajiv; Palit, V.; Loadman, Paul M.; Flannigan, G. Michael; Shah, T.K.; Choudry, G.A.; Basu, Saurajyoti; Double, John A.; Lenaz, G.; Chawla, S.; Beer, M.; Kalken, C.V.; de Boer, R.; Beijnen, J.H.; Twelves, Christopher J.; Phillips, Roger M. |
|---|
| |
| Title | Formation of DNA interstrand cross-links as a marker of Mitomycin C bioreductive activation and chemosensitivity (2005) |
|---|
| Authors | Volpato M.;Seargent J.;Loadman P.;Phillips R. |
|---|
| Journal | European Journal of Cancer. Part A |
|---|
| DOI | 10.1016/j.ejca.2005.03.014 |
|---|
| |
| Title | Expression of matrix metalloproteinase-10 in human bladder transitional cell carcinoma (2005) |
|---|
| Authors | Seargent J.;Loadman P.;Martin S.;Naylor B.;Bibby M.;Gill J. |
|---|
| Journal | Urology |
|---|
| DOI | 10.1016/j.urology.2004.11.016 |
|---|
| |
| Title | Immunohistochemical analysis of NAD(P)H:quinone oxidoreductase and NADPH cytochrome P450 reductase in human superficial bladder tumours: Relationship between tumour enzymology and clinical outcome following intravesical mitomycin C therapy (2004) |
|---|
| Authors | Basu, Saurajyoti; Brown, John E.; Flannigan, G. Michael; Gill, Jason H.; Loadman, Paul M.; Naylor, Brian; Scally, Andy J.; Seargent, Jill M.; Shah, Tariq K.; Puri, Rajiv; Phillips, Roger M.; Martin, Sandie W. |
|---|
| |
| Title | Comparative Preclinical Pharmacokinetic and Metabolic Studies of the Combretastatin Prodrugs Combretastatin A4 Phosphate and A1 Phosphate (2004) |
|---|
| Authors | Kirwan, Ian G.; Loadman, Paul M.; Swaine, David J.; Anthoney, Alan; Pettit, G.R.; Lippert III, J.W.; Shnyder, Steven D.; Cooper, Patricia A.; Bibby, Michael C. |
|---|
| |
| Title | NAD(P)H:Quinone oxidoreductase-1 C609T polymorphism analysis in human superficial bladder cancers: relationship of genotype status to NQO1 phenotype and clinical response to Mitomycin C. (2004) |
|---|
| Authors | Basu, Saurajyoti; Brown, John E.; Flannigan, G. Michael; Gill, Jason H.; Loadman, Paul M.; Martin, Sandie W.; Naylor, Brian; Puri, Rajiv; Scally, Andy J.; Seargent, Jill M.; Shah, Tariq K.; Phillips, Roger M. |
|---|
| |
| Title | Preliminary pharmacokinetic and bioanalytical studies of SJG-136 (NSC 694501), a sequence-selective pyrrolobenzodiazepine dimer DNA-cross-linking agent. (2004) |
|---|
| Authors | Wilkinson, Gary P.; Taylor, James P.; Shnyder, Steven D.; Loadman, Paul M.; Cooper, Patricia A.; Howard, P.W.; Thurston, D.E.; Jenkins, Terence C. |
|---|
| |
| Title | Pharmacological and biological evaluation of a series of substituted 1,4 naphthoquinone bioreductive drugs. (2004) |
|---|
| Authors | Phillips, Roger M.; Loadman, Paul M.; Maitland, Derek J.; Shnyder, Steven D.; Jaffar, M.; Steans, Gillian; Cooper, Patricia A.; Race, Amanda D.; Patterson, A.V.; Stratford, I.J. |
|---|
| |
| Title | MMP-10 is overexpressed, proteolytically active and a potential target for therapeutic intervention in human lung carcinomas (2004) |
|---|
| Authors | Gill, Jason H.; Kirwan, Ian G.; Seargent, Jill M.; Martin, Sandie W.; Tijani, S.; Anikin, V.A.; Mearns, A.J.; Bibby, Michael C.; Anthoney, Alan; Loadman, Paul M. |
|---|
| |
| Title | Detection of (NAD(P)H:Quinone oxidoreductase-1, EC 1.6.99.2) 609C-->T and 465C-->T polymorphisms in formalin-fixed, paraffin-embedded human tumour tissue using PCR-RFLP. (2004) |
|---|
| Authors | Phillips R.;Basu S.;Brown J.;Flannigan G.;Loadman P.;Martin S.;Naylor B.;Puri R.;Shah T. |
|---|
| Journal | International Journal of Oncology |
|---|
| |
| Title | Comet assay and flow cytometry analysis of DNA repair in normal and cancer cells treated with known mutagens with different mechanisms of action. (2003) |
|---|
| Authors | Suggitt M.;Fearnley J.;Swaine D.;Volpato M.;Phillips R.;Bibby M.;Loadman P.;Anderson D. |
|---|
| Journal | Teratogenesis Carcinogenesis and Mutagenesis |
|---|
| |
| Title | 5,6-Dimethylxanthenone-4-acetic acid (DMXAA), a novel antivascular agent: Phase I clinical and pharmacokinetic study (2003) |
|---|
| Authors | Rustin G.;Bradley C.;Galbraith S.;Stratford M.;Loadman P.;Waller S.;Bellenger K.;Gumbrell L.;Folkes L.;Halbert G. |
|---|
| Journal | British Journal of Cancer |
|---|
| DOI | 10.1038/sj.bjc.6600885 |
|---|
| |
| Title | Cytochrome P450 1B1 (CYP1B1) is over-expressed in human colon adeno-carcinomas relative to normal colon: Implications for drug development. (2003) |
|---|
| Authors | Gibson, Paul; Gill, Jason H.; Khan, Parveen A.; Seargent, Jill M.; Martin, Sandie W.; Batman, Philip A.; Griffith, John; Bradley, C.; Double, John A.; Bibby, Michael C.; Loadman, Paul M. |
|---|
| |
| Title | Pharmacological approach towards the development of indolequinone bioreductive drugs based on the clinically inactive agent EO9 (2002) |
|---|
| Authors | Loadman P.;Bibby M.;Phillips R. |
|---|
| Journal | British Journal of Pharmacology |
|---|
| DOI | 10.1038/sj.bjp.0704916 |
|---|
| |
| Title | A preclinical pharmacokinetic study of the bioreductive drug AQ4N (2001) |
|---|
| Authors | Loadman P.;Swaine D.;Bibby M.;Welham K.;Patterson L. |
|---|
| Journal | Drug Metabolism and Disposition |
|---|
| |
| Title | Pharmacological properties of a new aziridinylbenzoquinone, RH1 (2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone), in mice (2000) |
|---|
| Authors | Loadman P.;Phillips R.;Lim L.;Bibby M. |
|---|
| Journal | Biochemical Pharmacology |
|---|
| DOI | 10.1016/S0006-2952(99)00391-3 |
|---|
| |
| Title | Predicting tumor responses to mitomycin C on the basis of DT-diaphorase activity or drug metabolism by tumor homogenates: Implications for enzyme-directed bioreductive drug development (2000) |
|---|
| Authors | Phillips R.;Burger A.;Loadman P.;Jarrett C.;Swaine D.;Fiebig H. |
|---|
| Journal | Cancer Research |
|---|
| |
| Title | Combination chemotherapy with combretastatin A-4 phosphate and 5-fluorouracil in an experimental murine colon adenocarcinoma (2000) |
|---|
| Authors | Grosios K.;Loadman P.;Swaine D.;Pettit G.;Bibby M. |
|---|
| Journal | Anticancer Research |
|---|
| |
| Title | High-performance liquid chromatographic analysis of AQ4N, an alkylaminoanthraquinone N-oxide (2000) |
|---|
| Authors | Swaine D.;Loadman P.;Bibby M.;Graham M.;Patterson L. |
|---|
| Journal | Journal of Chromatography B: Biomedical Sciences and Applications |
|---|
| DOI | 10.1016/S0378-4347(00)00160-2 |
|---|
| |
| Title | In vivo metabolism of the antitumor imidazoacridinone C1311 in the mouse and in vitro comparison with humans (1999) |
|---|
| Authors | Calabrese C.;Loadman P.;Lim L.;Bibby M.;Double J.;Brown J.;Lamb J. |
|---|
| Journal | Drug Metabolism and Disposition |
|---|
| |
| Title | Pharmacokinetics of PK1 and doxorubicin in experimental colon tumor models with differing responses to PK1 (1999) |
|---|
| Authors | Loadman P.;Bibby M.;Double J.;Al-Shakhaa W.;Duncan R. |
|---|
| Journal | Clinical Cancer Research |
|---|
| |
| Title | Analysis of the imidazoacridinone C1311 by high-performance liquid chromatography (1997) |
|---|
| Authors | Calabrese C.;Loadman P. |
|---|
| Journal | JOURNAL OF CHROMATOGRAPHY B-BIOMEDICAL APPLICATIONS |
|---|
| DOI | 10.1016/S0378-4347(96)00387-8 |
|---|
| |
| Title | Extraction of the synthetic lytic peptide, cecropin B, from biological fluid and analysis using reversed-phase high-performance liquid chromatography (1995) |
|---|
| Authors | Moore A.;Loadman P.;Devine D.;Bibby M. |
|---|
| Journal | Journal of Chromatography - Biomedical Applications |
|---|
| DOI | 10.1016/0378-4347(95)00233-9 |
|---|
| |
| Title | Potentiation of EO9 anti-tumour activity by hydralazine (1993) |
|---|
| Authors | Bibby M.;Sleigh N.;Loadman P.;Double J. |
|---|
| Journal | European Journal of Cancer. Part A |
|---|
| DOI | 10.1016/S0959-8049(05)80218-7 |
|---|
| |
| Title | Pre-cinical evaluation of a novel chloroethylating agent, clomesone (1993) |
|---|
| Authors | Matthew A.;Phillips R.;Loadman P.;Bibby M. |
|---|
| Journal | British Journal of Cancer |
|---|
| DOI | 10.1038/bjc.1993.85 |
|---|
| |
| Title | The relationship between the in vitro chemosensitivity of tumor cells and tumor response in vivo in an experimental tumor model (1991) |
|---|
| Authors | Phillips R.;Bibby M.;Double J.;Loadman P. |
|---|
| Journal | International Journal of Cell Cloning |
|---|
| DOI | 10.1002/stem.5530090205 |
|---|
| |
| Title | Reduction of tumor blood flow by flavone acetic acid: A possible component of therapy (1989) |
|---|
| Authors | Bibby M.;Double J.;Loadman P.;Duke C. |
|---|
| Journal | Journal of the National Cancer Institute |
|---|
| DOI | 10.1093/jnci/81.3.216 |
|---|
| |
| Title | Factors involved in the anti-cancer activity of the investigational agents LM985 (Flavone acetic acid ester) and LM975 (flavone acetic acid) (1987) |
|---|
| Authors | Bibby M.;Double J.;Phillips R.;Loadman P. |
|---|
| Journal | British Journal of Cancer |
|---|
| DOI | 10.1038/bjc.1987.32 |
|---|
| |
| Title | Influence of the tissue distribution of ThioTEPA and its metabolite, TEPA, on the response of murine colon tumours (1987) |
|---|
| Authors | Bibby M.;McDermott B.;Double J.;Phillips R.;Loadman P.;Burgess L. |
|---|
| Journal | Cancer Chemotherapy and Pharmacology |
|---|
| DOI | 10.1007/BF00570485 |
|---|
| |
| Title | Gas chromatographic analysis of triethylenethiophosphoramide and triethylenephosphoramide in biological specimens (1985) |
|---|
| Authors | McDermott B.;Double J.;Bibby M.;Wilman D.;Loadman P.;Turner R. |
|---|
| Journal | Journal of Chromatography - Biomedical Applications |
|---|
| DOI | 10.1016/0378-4347(85)80104-3 |
|---|
| |
