Re-evaluating cyclosporine A as a hair growth-promoting agent in human scalp hair follicles
Hawkshaw, NJ; Haslam, IS; Ansell, David M; Shamalak, A; Paus, R (2015)
Dr. David Ansell
Assistant Professor
- Area
- School of Chemistry & Biosciences
- Faculty of Life Sciences
- Phone
Biography
I studied my PhD investigating "The role of hair follicles in wound repair" in the lab of Prof Mat Hardman at University of Manchester which I completed in 2012. Following this I spent 8 years as a postdoctoral researcher at Manchester, across the labs of Prof Hardman, Prof Ralf Paus group, then finally Prof Enrique Amaya. I set up my group in 2020 when I joined University of Bradford as Lecturer in Skin Science.
My research interests span several topics but I have a main focus on understand how wound healing is altered under impaired conditions, which might lead to chronic wounds. I have a PhD student examining the role of skin ageing and changes to vasculature on tissue viability. I also have projects studying the effect of biofilms and infection on skin integrity and wound repair. I also have an interest in hair follicle biology.
I have authored 20 journal papers, which have received 491 journal citations. My h index is 11.
Research
I have research interests in a broad range of Skin Science topics. Current projects include ranging from wound healing, skin ageing, hair follicle biology and the skin microbiome.
Teaching
Modules
- Skin Biology, Stem Cells and Regenerative Medicine - BIS7013-B
- Human Physiology, Biochemistry & Microbiology - PHA4014-D
- Cosmetic Science (Distance Learning) - CFS5027-B
- Cosmetic Science - CFS5026-B
- Cell Biology - BIS4016-B
- Cell and Tissue Biology - BIS4008-B
Publications
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Evaluating STZ-Induced Impaired Wound Healing in Rats.
Ansell DM;Marsh C;Walker L;Hardman MJ;Holden K; (2018) Journal of Investigative Dermatology.
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Ppia and ywhaz constitute a stable pair of reference genes during electrical stimulation in mesenchymal stem cells
Steel L.;Ansell D.M.;Amaya E.;Cartmell S.H. (2022) Applied Sciences (APPS). 12
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An epidermal-specific role for arginase1 during cutaneous wound repair.
Crompton RA;Williams H;Campbell L;Lim HK;Saville C;Ansell DM;Reid A;Wong J;Vardy LA;Hardman MJ;Cruickshank SM; (2021) Journal of Investigative Dermatology.
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Dermal adipose tissue secretes HGF to promote human hair growth and pigmentation.
Nicu C;O'Sullivan JDB;Ramos R;Timperi L;Lai T;Farjo N;Farjo B;Pople J;Bhogal R;Hardman JA;Plikus MV;Ansell DM;Paus R; (2021) Journal of Investigative Dermatology.
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Adiponectin negatively regulates pigmentation, Wnt/β-catenin and HGF/c-Met signalling within human scalp hair follicles ex vivo.
Nicu C;Jackson J;Shahmalak A;Pople J;Ansell D;Paus R; (2021) Archives of Dermatological Research.
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Neuroendocrinology and neurobiology of sebaceous glands
Clayton R.;Langan E.;Ansell D.;de Vos I.;Göbel K.;Schneider M.;Picardo M.;Lim X.;van Steensel M.;Paus R. (2020) Biological Reviews.
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Fluorescent cell tracer dye permits real-time assessment of re-epithelialization in a serum-free ex vivo human skin wound assay
Nasir N.;Paus R.;Ansell D. (2019) Wound Repair and Regeneration. 27, 126-133.
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Epithelial-to-mesenchymal stem cell transition in a human organ: Lessons from Lichen Planopilaris
Imanishi, H; Ansell, David M; Cheret, J; Harries, M; Bertolini, M; Sepp, N; Biro, T; Poblet, E; Jimenez, F; Hardman, J; Panicker, SP; Ward, CM; Paus, R (2018) Journal of Investigative Dermatology. 138
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A guide to studying human dermal adipocytes in situ.
Nicu C;Pople J;Bonsell L;Bhogal R;Ansell DM;Paus R; (2018) Experimental Dermatology. 27
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Wound healing protects against chemotherapy-induced alopecia in young rats via up-regulating interleukin-1β-mediated signaling
Stojadinovic O; Wikramanayake TC; Villasante Fricke AC; Yin NC; Liang L; Hinde E; Escandon J; Tomic-Canic M; Ansell DM; Paus R; Jimenez JJ (2017) Heliyon. 3
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The battle of the bulge: re-evaluating hair follicle stem cells in wound repair
Garcin, CL; Ansell, David M. (2017) Experimental Dermatology. 26
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Hair Follicle Bulge Stem Cells Appear Dispensable for the Acute Phase of Wound Re-epithelialization.
Garcin CL;Ansell DM;Headon DJ;Paus R;Hardman MJ; (2016) Stem Cells. 34
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Do not be alarmed: understanding IL33-ST2 signalling in wound repair.
Ansell DM;Hardman MJ; (2016) Experimental Dermatology. 25
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Oestrogen promotes healing in a bacterial LPS model of delayed cutaneous wound repair
Crompton, R; Williams, H; Ansell, David M; Campbell, L; Holden, K; Cruickshank, S; Hardman, MJ (2016) Laboratory Investigation. 96
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Pericytes in wound healing: friend or foe?
Ansell DM;Izeta A; (2015) Experimental Dermatology. 24
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A statistical analysis of murine incisional and excisional acute wound models
Ansell D.;Campbell L.;Thomason H.;Brass A.;Hardman M. (2014) Wound Repair and Regeneration. 22, 281-287.
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Animal models of wound repair: Are they cutting it?
Ansell DM;Holden KA;Hardman MJ; (2012) Experimental Dermatology. 21
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Direct evidence that PKCα positively regulates wound re-epithelialization: correlation with changes in desmosomal adhesiveness.
Thomason HA;Cooper NH;Ansell DM;Chiu M;Merrit AJ;Hardman MJ;Garrod DR; (2012) Journal of Pathology. 227
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Exploring the "hair growth-wound healing connection": anagen phase promotes wound re-epithelialization.
Ansell DM;Kloepper JE;Thomason HA;Paus R;Hardman MJ; (2011) Journal of Investigative Dermatology. 131
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A guide to studying human dermal adipocytes in situ
Nicu C.;Pople J.;Bonsell L.;Bhogal R.;Ansell D.;Paus R. (2018) Experimental Dermatology.