Dr. Venu Vangala
Biography
Venu Vangala joined as Lecturer in Medicines Development and Pharmaceutical Sciences. His research work focuses on building strong capability in interdisciplinary areas of fundamental and applied solid-state pharmaceuticals and pharmaceutical technology. Currently, he is involved in industrial collaborative projects with Advanced Extrusion Technology and N4 Pharma Ltd., UK.
Research
Crystal engineering for the development of functional pharmaceutical materials Solid state pharmaceuticals – cocrystals, polymorphs, salts and amorphous materials Physicochemical characterization of pharmaceutical solids Develop understanding of crystal structure vs pharmaceutical properties
Current Projects Screening and characterization of novel co-crystals involving active pharmaceutical ingredients.
Research Collaborations University of Minnesota, IISER Kolkata, University of Lucknow, University of Iowa.
Publications
Peer reviewed journal (15)
Interfacial Cocrystallization Using Oily Phase via Liquid−Liquid Phase Separation
M. Asim Sajid Al-Hanafi, Mhd Bashir Alsirawan, Colin C. Seaton, Thomas Swift, Sudhir Pagire, Venu R. Vangala, Adrian L. Kelly, and Anant Paradkar (2022) CRYSTAL GROWTH & DESIGN (ONLINE). 22
Cytochrome P450 Binding and Bioactivation of Tumor-targeted Duocarmycin Agents.
Bart AG;Morais G;Vangala VR;Loadman PM;Pors K;Scott EE; (2021) Drug Metabolism And Disposition: The Biological Fate Of Chemicals.
Solid-State Competitive Destabilization of Caffeine Malonic Acid cocrystal: Mechanistic and Kinetic Investigation
M. Bashir Alsirawan, Xiaojun Lai, Rafel Prohens, Venu Vangala, Sudhir Pagire, Petro Shelley, Thomas Bannan, David Topping, and Anant Paradkar (2020) Crystal Growth and Design. DOI: 10.1021/acs.cgd.0c01246
Mechanistic Understanding of Competitive Destabilization of Carbamazepine Cocrystals under Solvent Free Conditions
MHD Bashir Alsirawan, Xiaojun Lai, Rafel Prohens, Venu R. Vangala, Petroc Shelley, Thomas J. Bannan, David O. Topping, and Anant Paradkar (2020) CRYSTAL GROWTH & DESIGN (ONLINE). https://doi.org/10.1021/acs.cgd.0c00735
Structural Basis for Mechanical Anisotropy in Polymorphs of Caffeine-Glutaric Acid Cocrystal
Manish Kumar Mishra,* Kamini Mishra, Aditya Narayan, C. Malla Reddy* and Venu R. Vangala* (2020) CRYSTAL GROWTH & DESIGN (PRINT). 20
Intriguing High Z″ Cocrystals of Emtricitabine
Palanisamy V.;Sanphui P.;Bolla G.;Narayan A.;Seaton C.C.;Vangala V.R. (2020) Crystal Growth and Design. 20, 4886-4891.
Intriguing High Z'' Cocrystals of Emtricitabine
Vasanthi Palanisamy, Palash Sanphui, Geetha Bolla, Aditya Narayan, Colin C. Seatond and Venu R. Vangala (2020) CRYSTAL GROWTH & DESIGN (PRINT). 20
Isomorphism: 'Molecular similarity to crystal structure similarity' in multicomponent forms of analgesic drugs tolfenamic and mefenamic acid
Ranjan S.;Devarapalli R.;Kundu S.;Saha S.;Deolka S.;Vangala V.R.;Reddy C.M. (2020) Iucrj. 7, 173-183.
Nitrofurantoin-melamine monohydrate (cocrystal hydrate): Probing the role of H-bonding on the structure and properties using quantum chemical calculations and vibrational spectroscopy
Khan E.;Shukla A.;Jhariya A.;Tandon P.;Vangala V. (2019) Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy. 221
Structural and reactivity analyses of nitrofurantoin 4 dimethylaminopyridine salt using spectroscopic and density functional theory calculations
Khan E; Shukla A; Srivastava K; Gangopadhyay D; Assi K; Tandon P; Vangala V (2019) Crystals. 9
Thermodynamic investigation of carbamazepine-saccharin co-crystal polymorphs
Pagire, Sudhir K.; Jadav, Niten B.; Vangala, Venu R.; Whiteside, Benjamin R.; Paradkar, Anant R. (2017)
Three new hydrochlorothiazide cocrystals: Structural analyses and solubility studies
Ranjan, S.; Devarapalli, R.; Kundu, S.; Vangala, Venu R.; Ghosh, A.; Reddy, C.A. (2017)
Study of molecular interactions and chemical reactivity of the nitrofurantoin-3-aminobenzoic acid cocrystal using quantum chemical and spectroscopic (IR, Raman,13C SS-NMR) approaches
Shukla A.;Khan E.;Srivastava K.;Sinha K.;Tandon P.;Vangala V. (2017) CrystEngComm. 19, 3921-3930.
Study of molecular structure, chemical reactivity and H-bonding interactions in the cocrystal of nitrofurantoin with urea
Khan, E.; Shukla, A.; Jadav, Niten B.; Telford, Richard; Ayala, A.P.; Tandon, P.; Vangala, Venu R. (2017)
Thermal and in situ x-ray diffraction analysis of a dimorphic co-crystal 1:1 caffeine-glutaric acid
Vangala, Venu R.; Chow, P.S.; Schreyer, M.; Lau, G.; Tan, R.B.H. (2015)
Reviews (1)
Pharmaceutical Cocrystals: Molecules, Crystals, Formulations, Medicines
Yousef M.;Vangala V. (2019) Crystal Growth and Design.