Dr. Peter Nicholls

Biography
Teaching
Modules
- Practical Molecular Biology - BIS7027-B
- Molecular Genetics - BIS5014-B
- Molecular Biology - BIS5020-B
Professional activities
Awards (4)
- Hope Funds for Cancer Research Postdoctoral Research Fellowship (1 January 2015)
- NH&MRC CJ Martin Early Career Fellowship (1 January 2012)
- SRB New Investigator Award (1 January 2010)
- Australian Postgraduate Award (1 January 2008)
Education (5)
- Monash University - PhD
- Monash University (Australia) - Bachelor of Biomedical Science Honours
- Monash University (Australia) - Bachelor of Biomedical Sciences
- AdvanceHE - FHEA
- Marine Biological Laboratory, Woods Hole MA - Frontiers In Reproduction
Employment (2)
- University of Bradford - Lecturer in Molecular Biology (1 December 2020)
- Whitehead Institute (USA) - Postdoctoral Research Fellow (28 January 2013)
Publications
Peer reviewed journal (30)
Analysis of a mouse germ cell tumor model establishes pluripotency-associated miRNAs as conserved serum biomarkers for germ cell cancer detection
Amanda R Loehr;Dennis M Timmerman;Michelle Liu;Ad J Gillis;Melia Matthews;Jordana C Bloom;Peter K Nicholls;David C Page;Andrew D Miller;Leendert H J Looijenga;Robert S Weiss (2025) Scientific Reports. 15
A gene deriving from the ancestral sex chromosomes was lost from the X and retained on the Y chromosome in eutherian mammals.
Hughes JF;Skaletsky H;Nicholls PK;Drake A;Pyntikova T;Cho TJ;Bellott DW;Page DC; (2022) BMC Biology. 20
Advancing clinical and translational research in germ cell tumours (GCT): recommendations from the Malignant Germ Cell International Consortium.
Fonseca A;Lobo J;Hazard FK;Gell J;Nicholls PK;Weiss RS;Klosterkemper L;Volchenboum SL;Nicholson JC;Frazier AL;Amatruda JF;Bagrodia A;Lockley M;Murray MJ; (2022) British Journal of Cancer. 127
Germ cell determination and the developmental origin of germ cell tumors.
Nicholls PK;Page DC; (2021) Development - Company of Biologists. 148
DAZL mediates a broad translational program regulating expansion and differentiation of spermatogonial progenitors.
Mikedis MM;Fan Y;Nicholls PK;Endo T;Jackson EK;Cobb SA;de Rooij DG;Page DC; (2020) eLife. 9
GCNA Interacts with Spartan and Topoisomerase II to Regulate Genome Stability.
Dokshin GA;Davis GM;Sawle AD;Eldridge MD;Nicholls PK;Gourley TE;Romer KA;Molesworth LW;Tatnell HR;Ozturk AR;de Rooij DG;Hannon GJ;Page DC;Mello CC;Carmell MA; (2020) Developmental Cell. 52
Mammalian germ cells are determined after PGC colonization of the nascent gonad.
Nicholls PK;Schorle H;Naqvi S;Hu YC;Fan Y;Carmell MA;Dobrinski I;Watson AL;Carlson DF;Fahrenkrug SC;Page DC; (2019) Proceedings of the National Academy of Sciences of the United States of America. 116
Retinoic Acid and Germ Cell Development in the Ovary and Testis.
Endo T;Mikedis MM;Nicholls PK;Page DC;de Rooij DG; (2019) Biomolecules. 9
Locating and Characterizing a Transgene Integration Site by Nanopore Sequencing.
Nicholls PK;Bellott DW;Cho TJ;Pyntikova T;Page DC; (2019) G3: Genes, Genomes, Genetics. 9
Suppression of Sertoli cell tumour development during the first wave of spermatogenesis in inhibin α-deficient mice.
Haverfield JT;Stanton PG;Loveland KL;Zahid H;Nicholls PK;Olcorn JS;Makanji Y;Itman CM;Simpson ER;Meachem SJ; (2017) Reproduction, Fertility and Development. 29
A mitotic SKAP isoform regulates spindle positioning at astral microtubule plus ends.
Kern DM;Nicholls PK;Page DC;Cheeseman IM; (2016) Journal of Cell Biology. 213
Licensing of primordial germ cells for gametogenesis depends on genital ridge signaling.
Hu YC;Nicholls PK;Soh YQ;Daniele JR;Junker JP;van Oudenaarden A;Page DC; (2015) PLoS Genetics. 11
The E2 ubiquitin-conjugating enzyme UBE2J1 is required for spermiogenesis in mice.
Koenig PA;Nicholls PK;Schmidt FI;Hagiwara M;Maruyama T;Frydman GH;Watson N;Page DC;Ploegh HL; (2014) Journal of Biological Chemistry. 289
Differential permeability of the blood-testis barrier during reinitiation of spermatogenesis in adult male rats.
Haverfield JT;Meachem SJ;Nicholls PK;Rainczuk KE;Simpson ER;Stanton PG; (2014) Endocrinology. 155
Retinoic acid promotes Sertoli cell differentiation and antagonises activin-induced proliferation.
Nicholls PK;Harrison CA;Rainczuk KE;Wayne Vogl A;Stanton PG; (2013) Molecular and Cellular Endocrinology. 377
A novel subcellular machine contributes to basal junction remodeling in the seminiferous epithelium.
Du M;Young J;De Asis M;Cipollone J;Roskelley C;Takai Y;Nicholls PK;Stanton PG;Deng W;Finlay BB;Vogl AW; (2013) Biology of Reproduction. 88
Proprotein convertases in post-menopausal endometrial cancer: distinctive regulation and non-invasive diagnosis.
Singh H;Heng S;Nicholls PK;Li Y;Tai LT;Jobling T;Salamonsen LA;Nie G; (2012) Biochemical and Biophysical Research Communications. 419
Androgen initiates Sertoli cell tight junction formation in the hypogonadal (hpg) mouse.
McCabe MJ;Allan CM;Foo CF;Nicholls PK;McTavish KJ;Stanton PG; (2012) Biology of Reproduction. 87
Activin signaling regulates Sertoli cell differentiation and function.
Nicholls PK;Stanton PG;Chen JL;Olcorn JS;Haverfield JT;Qian H;Walton KL;Gregorevic P;Harrison CA; (2012) Endocrinology. 153
Lentiviral transduction of rat Sertoli cells as a means to modify gene expression.
Nicholls PK;Stanton PG;Rainczuk KE;Qian H;Gregorevic P;Harrison CA; (2012) Spermatogenesis. 2
Hormonal regulation of sertoli cell micro-RNAs at spermiation.
Nicholls PK;Harrison CA;Walton KL;McLachlan RI;O'Donnell L;Stanton PG; (2011) Endocrinology. 152
Spermiation: The process of sperm release.
O'Donnell L;Nicholls PK;O'Bryan MK;McLachlan RI;Stanton PG; (2011) Spermatogenesis. 1
Embryo implantation is closely associated with dynamic expression of proprotein convertase 5/6 in the rabbit uterus.
Nicholls PK;Sun Z;Heng S;Li Y;Wang J;Nie G; (2011) Reproductive biology and endocrinology : RB&E. 9
Interleukin 11 is upregulated in uterine lavage and endometrial cancer cells in women with endometrial carcinoma.
Yap J;Salamonsen LA;Jobling T;Nicholls PK;Dimitriadis E; (2010) Reproductive biology and endocrinology : RB&E. 8
Post-translational modifications and protein-specific isoforms in endometriosis revealed by 2D DIGE.
Stephens AN;Hannan NJ;Rainczuk A;Meehan KL;Chen J;Nicholls PK;Rombauts LJ;Stanton PG;Robertson DM;Salamonsen LA; (2010) Journal of Proteome Research. 9
Loss of betaglycan contributes to the malignant properties of human granulosa tumor cells.
Bilandzic M;Chu S;Farnworth PG;Harrison C;Nicholls P;Wang Y;Escalona RM;Fuller PJ;Findlay JK;Stenvers KL; (2009) Molecular Endocrinology. 23
Extra-ovarian expression and activity of growth differentiation factor 9.
Wang Y;Nicholls PK;Stanton PG;Harrison CA;Sarraj M;Gilchrist RB;Findlay JK;Farnworth PG; (2009) Journal of Endocrinology. 202
Growth differentiation factor 9 is a germ cell regulator of Sertoli cell function.
Nicholls PK;Harrison CA;Gilchrist RB;Farnworth PG;Stanton PG; (2009) Endocrinology. 150
Proteomic characterization of midproliferative and midsecretory human endometrium.
Chen JI;Hannan NJ;Mak Y;Nicholls PK;Zhang J;Rainczuk A;Stanton PG;Robertson DM;Salamonsen LA;Stephens AN; (2009) Journal of Proteome Research. 8
Expression of nodal signalling components in cycling human endometrium and in endometrial cancer.
Papageorgiou I;Nicholls PK;Wang F;Lackmann M;Makanji Y;Salamonsen LA;Robertson DM;Harrison CA; (2009) Reproductive biology and endocrinology : RB&E. 7