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researcher

Anant Paradkar

Professor of Pharmaceutical Engineering

Faculty/Dept/School School of Pharmacy and Medical Sciences
(Faculty of Life Sciences)
Emaila.paradkar1@bradford.ac.uk
Telephone +441274 233900

Biography

Professor Anant Paradkar holds an Interdisciplinary Chair in Pharmaceutical Engineering Science and is Director of the Centre for Pharmaceutical Engineering Science. He completed his PhD in Pharmaceutics and joined Bradford following a 20 year academic career in India. He has worked on various interdisciplinary collaborative research projects in the areas of process development and crystal and particle engineering, developing techniques such as crystallo-co-agglomeration, melt granulation, sono-crystallisation, spray drying of low Tg materials and liquid crystal precursors. He is currently working on the application of hot melt extrusion and sono-crystallisation to generate co-crystals and has been awarded a EPSRC funding and Yorkshire Enterprise Fellowship to strengthen exploitation and impact of this work. In India, he received research funding from the All India Council for Technical Education, University Grants Commission, Department of Science and Technology and the Ministry of Defence. He has received an India-JSPS International Joint project on liquid crystalline systems, UK-India Education and Research Initiative (UKIERI) Fellowship and a Royal Society UK-India Science Network award He has supervised 10 PhD and 45 MPharm candidates and published over 90 research papers. Currently, he is supervising/ co-supervising 15 PhD students in various areas of research. Awards and Recognition: 2010: Business Innovation Award, University of Bradford 2010: Finalist, Yorkshire Forward Innovator10 Award 2009: Yorkshire Enterprise Fellowship 2009: Research and Knowledge Transfer Showcase Award for interdisciplinary research presentation 2007: UK India Education and Research Initiative (UKIERI) Fellowship 2006: Bharati Vidyapeeth Best Employee of the University 2005: Indo-UK Science Network Scheme (Royal Society and DST, India) 2005: India-JSPS funded India-Japan Cooperation Programme (IJCP) 2005: Young Pharmacy Teacher Award by Association of Pharmaceutical Teachers of India (APTI) Professor Anant Paradkar holds an Interdisciplinary Chair in Pharmaceutical Engineering Science and is Director of the Centre for Pharmaceutical Engineering Science. He completed his PhD in Pharmaceutics and joined Bradford following a 20 year academic career in India. He has worked on various interdisciplinary collaborative research projects in the areas of process development and crystal and particle engineering, developing techniques such as crystallo-co-agglomeration, melt granulation, sono-crystallisation, spray drying of low Tg materials and liquid crystal precursors. He is currently working on the application of hot melt extrusion and sono-crystallisation to generate co-crystals and has been awarded a EPSRC funding and Yorkshire Enterprise Fellowship to strengthen exploitation and impact of this work. In India, he received research funding from the All India Council for Technical Education, University Grants Commission, Department of Science and Technology and the Ministry of Defence. He has received an India-JSPS International Joint project on liquid crystalline systems, UK-India Education and Research Initiative (UKIERI) Fellowship and a Royal Society UK-India Science Network award He has supervised 10 PhD and 45 MPharm candidates and published over 90 research papers. Currently, he is supervising/ co-supervising 15 PhD students in various areas of research. Awards and Recognition: 2010: Business Innovation Award, University of Bradford 2010: Finalist, Yorkshire Forward Innovator10 Award 2009: Yorkshire Enterprise Fellowship 2009: Research and Knowledge Transfer Showcase Award for interdisciplinary research presentation 2007: UK India Education and Research Initiative (UKIERI) Fellowship 2006: Bharati Vidyapeeth Best Employee of the University 2005: Indo-UK Science Network Scheme (Royal Society and DST, India) 2005: India-JSPS funded India-Japan Cooperation Programme (IJCP) 2005: Young Pharmacy Teacher Award by Association of Pharmaceutical Teachers of India (APTI)

Research

Process Development: Currently my research focus is on non-infringing processing technologies for pharmaceuticals with special emphasis on Hot Melt Extrusion ( HME) and Ultrasound Assisted processing. Our interdisciplinary team has developed application of HME for co-crystallization. This solvent free continuous technology offers many advantages and easy for scale-up and commercialization. In process development we also focus on process optimization and characterization of process related properties like extensional rheology. In this area our group has linkages with Professor Guos group at Sichuan University, China and Dr. Kumarswamy and Dr. Suresh Bhat at National Chemical Laboratory, India. Technology Opportunity Solvent-Free Continuous Technology for Co-crystallization Formulation Development: In the area of formulation development my focus is poorly soluble drug and nutraceutical molecules. Development of amorphous systems and liquid crystalline systems are adopted for different purposes. The novel drug delivery concepts are also extended to molecules from natural products. We are developing nanoparticulate delivery systems for treatment of neurodegenerative conditions, cancers and endometriosis. METRC Process Analytical Technology: The interdisciplinary group provides us with strong engineering expertise required for process analytics. Application of in-line measurement systems are being used to understand the mechanisms of novel products developed and process optimization. Solid State Pharmaceutics: Crystal and Particle Engineering: Green technologies for particle engineering including Extrusion, ultrasound and microwaves Amorphous State Pharmaceuticals: Hot Melt Extrusion, Spray Drying especially low Tg drugs and stabilization using amphiphilic lipids Molecular Pharmaceutics: Rheological basis for process and formulation performance Molecular aspects in biopharmaceutical performance of targeted systems Molecular basis for stabilized amorphous systems Role of extensional rheology in melt extrusion Novel Drug Delivery Systems: Polymeric controlled release systems. Major focus on transdermal drug delivery system Microneedle and Magnetic Microarray Technologies for transdermal drug delivery Liquid crystalline phases and their solid state precursors Inhaled drug delivery systems Moulded tablets, Porous polymer matrices Nanoparticulate delivery systems Phytopharmaceuticals and Nutraceuticals: Applications of modern principles in design of extraction processes and delivery systems for phytochemicals and nutraceuticals QbD and Process Analytical Technology (PAT): In –line rheology, spectroscopy (NIR, Raman) and ultrasound transmission Advanced statistical techniques: DoE, modelling, response surface methods Computational and Predictive Pharmaceutics: ANN, Neurofuzzy logic, Mesoscale simulations Process Development: Currently my research focus is on non-infringing processing technologies for pharmaceuticals with special emphasis on Hot Melt Extrusion ( HME) and Ultrasound Assisted processing. Our interdisciplinary team has developed application of HME for co-crystallization. This solvent free continuous technology offers many advantages and easy for scale-up and commercialization. In process development we also focus on process optimization and characterization of process related properties like extensional rheology. In this area our group has linkages with Professor Guos group at Sichuan University, China and Dr. Kumarswamy and Dr. Suresh Bhat at National Chemical Laboratory, India. Technology Opportunity Solvent-Free Continuous Technology for Co-crystallization Formulation Development: In the area of formulation development my focus is poorly soluble drug and nutraceutical molecules. Development of amorphous systems and liquid crystalline systems are adopted for different purposes. The novel drug delivery concepts are also extended to molecules from natural products. We are developing nanoparticCurrent Projects A Novel Continuous Method for Co-crystal Formation, EPSRC (EP/J003360/1) Development of Propolis Products, Technology Strategy Board KTP Scheme Nanoparticulate Curcumin System with enhancers from Traditional Chinese Medicine (TCM) for treatment of Alzheimers, Changzhou People’s Hospital

Publications

Peer Reviewed Journal
TitleUnderstanding Matrix Assisted Continuous Cocrystallisation using Data Mining approach in Quality by Design (QbD)* (2020)
AuthorsBilly Chabalenge, Sachin Korde, Adrian L Kelly, Daniel Neagu and Anant Paradkar
JournalCrystal Growth and Design
PublisherACS
DOIhttps://doi.org/10.1021/acs.cgd.0c00338
 
TitleImproving Stability of Effervescent Products by Co-Crystal Formation: A Novel Application of Crystal Engineered Citric Acid (2020)
AuthorsPagire, SK; Seaton, CC; Paradkar, A
JournalCrystal Growth and Design
PublisherACS
DOIhttps://doi.org/10.1021/acs.cgd.0c00616
 
TitleHot-melt extrusion process impact on polymer choice of glyburide solid dispersions: The effect of wettability and dissolution. (2019)
AuthorsAlshafiee M;Aljammal MK;Markl D;Ward A;Walton K;Blunt L;Korde S;Pagire SK;Kelly AL;Paradkar A;Conway BR;Asare-Addo K;
JournalInternational Journal of Pharmaceutics
DOI10.1016/j.ijpharm.2019.01.038
 
TitleGaps in Propolis Research: Challenges Posed to Commercialisation and the Need for an Holistic Approach (2019)
AuthorsKatekhaye, S.; Fearnley, H.; Fearnley, J.; Paradkar, Anant R.
 
TitlePolymorphs of Curcumin and Its Cocrystals With Cinnamic Acid (2019)
AuthorsRathi, N.; Paradkar, Anant R.; Gaikar, V.G.
 
TitleDevelopment and evaluation of nanoemulsion and microsuspension formulations of curcuminoids for lung delivery with a novel approach to understanding the aerosol performance of nanoparticles (2019)
AuthorsAl Ayoub, Yuosef; Gopalan, Rajendran C.; Najafzadeh, Mojgan; Mohammad, Mohammad A.; Anderson, Diana; Paradkar, Anant R.; Assi, Khaled H.
 
TitleDevelopment and evaluation of nanoemulsion and microsuspension formulations of curcuminoids for lung delivery with a novel approach to understanding the aerosol performance of nanoparticles (2019)
AuthorsAl ayoub Y.;Gopalan R.;Najafzadeh M.;Mohammad M.;Anderson D.;Paradkar A.;Assi K.
JournalInternational Journal of Pharmaceutics
DOI10.1016/j.ijpharm.2018.12.042
 
TitleInjection Moulded Controlled Release Amorphous Solid Dispersions: Synchronized Drug and Polymer Release for Robust Performance. (2019)
AuthorsDeshmukh S;Paradkar A;Abrahmsén-Alami S;Govender R;Viridén A;Winge F;Matic H;Booth J;Kelly A;
JournalInternational Journal of Pharmaceutics
DOI10.1016/j.ijpharm.2019.118908
 
TitlePolymorphs of Curcumin and Its Cocrystals With Cinnamic Acid (2019)
AuthorsRathi N.;Paradkar A.;Gaikar V.
JournalJournal of Pharmaceutical Sciences
DOI10.1016/j.xphs.2019.03.014
 
TitleApplication of hot melt extrusion for improving bioavailability of artemisinin a thermolabile drug (2018)
AuthorsKulkarni C.;Kelly A.;Gough T.;Jadhav V.;Singh K.;Paradkar A.
JournalDrug Development and Industrial Pharmacy
DOI10.1080/03639045.2017.1386200
 
TitleCombined Virtual/Experimental Multicomponent Solid Forms Screening of Sildenafil: New Salts, Cocrystals and Hybrid Salt-Cocrystals (2018)
AuthorsRafael Barbas, Merce Font-Bardia, Anant Paradkar, Christopher A. Hunter, and Rafel Prohens
JournalCRYSTAL GROWTH & DESIGN (ONLINE)
PublisherACS
DOI10.1021/acs.cgd.8b01413
 
TitleNovel nicotinamide skin-adhesive hot melt extrudates for treatment of acne (2018)
AuthorsNasr M.;Karandikar H.;Abdel-Aziz R.;Moftah N.;Paradkar A.
JournalEXPERT OPINION ON DRUG DELIVERY
DOI10.1080/17425247.2018.1546287
 
TitleNovel nicotinamide skin-adhesive hot melt extrudates for treatment of acne (2018)
AuthorsMaha Nasr, Hrushikesh Karandikar, Rasha T.A. Abdel-Aziz, Noha Moftah, Anant Paradkar
JournalEXPERT OPINION ON DRUG DELIVERY
PublisherTaylor and Francis
DOI10.1080/17425247.2018.154628
 
TitleNovel nicotinamide skin-adhesive hot melt extrudates for treatment of acne (2018)
AuthorsNasr, M.; Karandikar, H.; Abdel-Aziz, R.T.A.; Moftah, N.; Paradkar, Anant R.
 
TitleCombined virtual/experimental multicomponent solid forms screening of sildenafil: new salts, cocrystals, and hybrid salt-cocrystals (2018)
AuthorsBarbas, R.; Font-Bardia, M.; Paradkar, Anant R.; Hunter, C.A.; Prohens, R.
 
TitleContinuous Manufacturing of Cocrystals Using Solid State Shear Milling Technology (2018)
AuthorsKorde, Sachin A.; Pagire, Sudhir K.; Pan, H.; Seaton, Colin C.; Kelly, Adrian L.; Chen, Y.; Wang, Q.; Coates, Philip D.; Paradkar, Anant R.
 
TitleIn-process rheometry as a PAT tool for hot melt extrusion (2018)
AuthorsKelly, Adrian L.; Gough, Timothy D.; Isreb, Mohammad; Dhumal, Ravindra S.; Jones, J.W.; Nicholson, S.; Dennis, A.B.; Paradkar, Anant R.
 
TitleDevelopment of stability-enhanced ternary solid dispersions via combinations of HPMCP and Soluplus®processed by hot melt extrusion (2017)
AuthorsAlbadarin A.;Potter C.;Davis M.;Iqbal J.;Korde S.;Pagire S.;Paradkar A.;Walker G.
JournalInternational Journal of Pharmaceutics
DOI10.1016/j.ijpharm.2017.09.035
 
TitleProfessor Peter York—A Distinguished Career in Powders, Processing, and Particle Design (2017)
AuthorsTaylor L.;Rantanen J.;Paradkar A.;Kawashima Y.;Zhang J.
JournalJournal of Pharmaceutical Sciences
DOI10.1016/j.xphs.2016.09.006
 
TitleSynthesis of caffeine/maleic acid co-crystal by ultrasound assisted slurry co-crystallization (2017)
AuthorsApshingekar, Prafulla P.; Aher, Suyog; Kelly, Adrian L.; Brown, Elaine C.; Paradkar, Anant R.
 
TitleThermodynamic investigation of carbamazepine-saccharin co-crystal polymorphs (2017)
AuthorsPagire, Sudhir K.; Jadav, Niten B.; Vangala, Venu R.; Whiteside, Benjamin R.; Paradkar, Anant R.
 
TitleMechanism of hydrogen-bonded complex formation between ibuprofen and nanocrystalline hydroxyapatite (2017)
AuthorsRyabenkova, Yulia; Jadav, Niten B.; Conte, M.; Hippler, M.F.A.; Reeves-McLaren, N.; Coates, Philip D.; Twigg, Peter C.; Paradkar, Anant R.
 
TitleApplication of hot melt extrusion for improving bioavailability of artemisinin a thermolabile drug (2017)
AuthorsKulkarni, Chaitrali S.; Kelly, Adrian L.; Gough, Timothy D.; Jadhav, V.; Singh, K.; Paradkar, Anant R.
 
TitleUltrasound-assisted preparation of novel ibuprofen-loaded excipient with improved compression and dissolution properties (2016)
AuthorsGandhi P.;Patil S.;Aher S.;Paradkar A.
JournalDrug Development and Industrial Pharmacy
DOI10.3109/03639045.2016.1151035
 
TitleDesign, synthesis, pharmacological evaluation and molecular docking studies of substituted oxadiazolyl-2-oxoindolinylidene propane hydrazide derivatives (2016)
AuthorsKerzare D.;Chikhale R.;Bansode R.;Amnerkar N.;Karodia N.;Paradkar A.;Khedekar P.
JournalJournal of the Brazilian Chemical Society
DOI10.5935/0103-5053.20160090
 
TitleCoformer Replacement as an Indicator for Thermodynamic Instability of Cocrystals: Competitive Transformation of Caffeine:Dicarboxylic Acid (2016)
AuthorsAlsirawan, M.H.D. Bashir; Vangala, Venu R.; Kendrick, John; Leusen, Frank J.J.; Paradkar, Anant R.
DOIAlsirawan MHD B, Vangala VR, Kendrick J, Leusen FJJ and Paradkar A (2016) Coformer Replacement as an Indicator for Thermodynamic Instability of Cocrystals: Competitive Transformation of Caffeine:Dicarboxylic Acid. Crystal growth & design. Online before print, May 2016. DOI http://dx.doi.org/10.1021/acs.cgd.6b00458
 
TitleTracing the architecture of caffeic acid phenethyl ester cocrystals: studies on crystal structure, solubility, and bioavailability implications (2016)
AuthorsKetkar, S.S.; Pagire, Sudhir K.; Goud, N.R.; Mahadik, K.R.; Nangia, A.; Paradkar, Anant R.
 
TitleNear infra red spectroscopy as a multivariate process analytical tool for predicting pharmaceutical co-crystal concentration (2016)
AuthorsWood, Clive; Alwati, Abdolati; Halsey, S.A.; Gough, Timothy D.; Brown, Elaine C.; Kelly, Adrian L.; Paradkar, Anant R.
 
TitleDesign, synthesis and pharmacological evaluation of pyrimidobenzothiazole-3-carboxylate derivatives as selective L-type calcium channel blockers (2016)
AuthorsChikhale, R.; Thorat, S.; Pant, A.; Jadhav, A.; Thatipamula, K.C.; Bansode, Ratnadeep V.; Bhargavi, G.; Karodia, Nazira; Rajasekharan, M.V.; Paradkar, Anant R.; Khedekar, Pramod
 
TitleDesign, synthesis and pharmacological evaluation of pyrimidobenzothiazole-3-carboxylate derivatives as selective L-type calcium channel blockers (2015)
AuthorsChikhale R.;Thorat S.;Pant A.;Jadhav A.;Thatipamula K.;Bansode R.;Bhargavi G.;Karodia N.;Rajasekharan M.;Paradkar A.;Khedekar P.
JournalBioorganic and Medicinal Chemistry
DOI10.1016/j.bmc.2015.09.009
 
TitleLiquid crystalline phase as a probe for crystal engineering of lactose: Carrier for pulmonary drug delivery (2015)
AuthorsPatil S.;Mahadik K.;Paradkar A.
JournalEuropean Journal Of Pharmaceutical Sciences
DOI10.1016/j.ejps.2014.11.007
 
TitleAlleviating exercise-induced muscular stress using neat and processed bee pollen: oxidative markers, mitochondrial enzymes, and myostatin expression in rats (2015)
AuthorsKetkar, S.S.; Rathore, A.S.; Kandhare, A.; Lohidasan, S.; Bodhankar, S.; Paradkar, Anant R.; Mahadik, K.R.
 
TitleExploring Microstructural Changes in Structural Analogues of Ibuprofen-Hosted In Situ Gelling System and Its Influence on Pharmaceutical Performance (2015)
AuthorsPatil, S.S.; Venugopal, E.; Bhat, S.; Mahadik, K.R.; Paradkar, Anant R.
 
TitleCan green synthesized propolis loaded silver nanoparticulate gel enhance wound healing caused by burns? (2015)
AuthorsPatil, S.S.; Desai, N.; Mahadik, K.R.; Paradkar, Anant R.
 
TitleControlled release floating multiparticulates of metoprolol succinate by hot melt extrusion (2015)
AuthorsMalode, V.N.; Paradkar, Anant R.; Devarajan, P.V.
 
TitleInvestigation of Plasma Treatment on Micro-Injection Moulded Microneedle for Drug Delivery (2015)
AuthorsNair, Karthik Jayan; Whiteside, Benjamin R.; Grant, Colin A.; Patel, Rajnikant; Tuinea-Bobe, Cristina-Luminita; Norris, Keith; Paradkar, Anant R.
 
TitleStoichiometric control of co-crystal formation by solvent free continuous co-crystallization (SFCC). (2015)
AuthorsKulkarni, Chaitrali S.; Wood, Clive; Kelly, Adrian L.; Gough, Timothy D.; Blagden, Nicholas; Paradkar, Anant R.
 
TitleA novel transflectance near infrared spectroscopy technique for monitoring hot melt extrusion (2015)
AuthorsKelly, Adrian L.; Halsey, S.A.; Bottom, R.A.; Korde, Sachin A.; Gough, Timothy D.; Paradkar, Anant R.
 
TitleDevelopment of selective DprE1 inhibitors: Design, synthesis, crystal structure and antitubercular activity of benzothiazolylpyrimidine-5-carboxamides (2015)
AuthorsChikhale, R.; Menghani, S.; Babu, R.; Bansode, Ratnadeep V.; Bhargavi, G.; Karodia, Nazira; Rajasekharan, M.V.; Paradkar, Anant R.; Khedekar, Pramod
 
TitleSystematic identification of thermal degradation products of HPMCP during hot melt extrusion process (2015)
AuthorsKarandikar, Hrushikesh M.; Ambardekar, Rohan; Kelly, Adrian L.; Gough, Timothy D.; Paradkar, Anant R.
 
TitleA comparative study of the effect of spray drying and hot-melt extrusion on the properties of amorphous solid dispersions containing felodipine (2014)
AuthorsMahmah, O.; Tabbakh, R.; Kelly, Adrian L.; Paradkar, Anant R.
 
TitleEffect of Ultrasound on Molecular Structure Development of Polylactide (2014)
AuthorsBao, W.; Wu, H.; Guo, S.; Paradkar, Anant R.; Kelly, Adrian L.; Brown, Elaine C.; Coates, Philip D.
 
TitleExtrusion-Spheronization of Talc using Microcrystalline Cellulose as a Pellet Aid: Part I (2014)
AuthorsJadhav, N.; Gade, M.; Salunkhe, N.; Paradkar, Anant R.
 
TitleInvestigation of the nutraceutical potential of monofloral Indian mustard bee pollen (2014)
AuthorsKetkar, S.S.; Rathore, A.S.; Lohidasan, S.; Rao, L.; Paradkar, Anant R.; Mahadik, K.R.
 
TitleMicrowave assisted synthesis of caffeine/maleic acid co-crystals: The role of the dielectric and physicochemical properties of the solvent (2013)
AuthorsPagire S.;Korde S.;Ambardekar R.;Deshmukh S.;Dash R.;Dhumal R.;Paradkar A.
JournalCrystEngComm
DOI10.1039/c3ce40292d
 
TitleMapping ion-induced mesophasic transformation in lyotropic in situ gelling system and its correlation with pharmaceutical performance (2013)
AuthorsPatil S.;Venugopal E.;Bhat S.;Mahadik K.;Paradkar A.
JournalPharmaceutical Research
DOI10.1007/s11095-013-1033-4
 
TitleAdsorption studies of bromhexine hydrochloride on talc (2013)
AuthorsJadhav N.;Paradkar A.;Shah G.
JournalResearch Journal of Pharmacy and Technology
 
TitleEnhanced brain targeting of curcumin by intranasal administration of a thermosensitive poloxamer hydrogel (2013)
AuthorsChen X.;Zhi F.;Jia X.;Zhang X.;Ambardekar R.;Meng Z.;Paradkar A.;Hu Y.;Yang Y.
JournalJournal of Pharmacy and Pharmacology
DOI10.1111/jphp.12043
 
TitleIsolation, biochemical and genetic characterizations of alcohol-producing yeasts from the flowers of Woodfordia fruticosa (2013)
AuthorsManwar J.;Mahadik K.;Paradkar A.;Sathiyanarayanan L.;Vohra M.;Patil S.
JournalJournal of Young Pharmacists
DOI10.1016/j.jyp.2013.11.007
 
TitlePolymorphic transformation of artemisinin by high temperature extrusion (2013)
AuthorsKulkarni, Chaitrali S.; Kendrick, John; Kelly, Adrian L.; Gough, Timothy D.; Dash, Radha C.; Paradkar, Anant R.
 
TitleA quality by design approach using artificial intelligence techniques to control the critical quality attributes of ramipril tablets manufactured by wet granulation (2013)
AuthorsAksu, B.; Paradkar, Anant R.; de Matas, Marcel; Özer, Ö.; Güneri, T.; York, Peter
 
TitleEffect of cocrystallization techniques on compressional properties of caffeine/oxalic acid 2:1 cocrystal (2013)
AuthorsAher, Suyog; Dhumal, Ravindra S.; Mahadik, K.R.; Ketolainen, J.; Paradkar, Anant R.
 
TitleSpherical Crystallization of Carbamazepine/Saccharin Co-Crystals: Selective Agglomeration and Purification through Surface Interactions (2013)
AuthorsPagire, Sudhir K.; Korde, Sachin A.; Whiteside, Benjamin R.; Kendrick, John; Paradkar, Anant R.
 
TitleMechanism for Polymorphic Transformation of Artemisinin during High Temperature Extrusion (2013)
AuthorsKulkarni, Chaitrali S.; Kelly, Adrian L.; Kendrick, John; Gough, Timothy D.; Paradkar, Anant R.
 
TitleYeast consortium isolated from Woodfordia fruticosa flowers proved to be instrumental for traditional Ayurvedic fermentation (2013)
AuthorsBhondave, P.; Burase, R.; Takale, S.; Paradkar, Anant R.; Patil, S.; Mahadik, K.R.; Harsulkar, A.
 
TitleEnhancement of hepatoprotective efficacy of propolis by fabrication of liposomes, as a platform nano-formulation for multi-component natural medicine (2012)
AuthorsAmbardekar R.;Mahadik K.;Paradkar A.;Harsulkar A.
JournalCurrent Drug Delivery
DOI10.2174/156720112802650653
 
TitleApoE3 mediated polymeric nanoparticles containing curcumin: Apoptosis induced in vitro anticancer activity against neuroblastoma cells (2012)
AuthorsMulik R.;Mönkkönen J.;Juvonen R.;Mahadik K.;Paradkar A.
JournalInternational Journal of Pharmaceutics
DOI10.1016/j.ijpharm.2012.07.062
 
TitleCharacterization of Cashew nut gum as a binder in tablet formulation (2012)
AuthorsWairkar S.;Ambike A.;Paradkar A.
JournalJournal of International Pharmaceutical Research
 
TitleMonitoring ibuprofen-nicotinamide cocrystal formation during solvent free continuous cocrystallization (SFCC) using near infrared spectroscopy as a PAT tool (2012)
AuthorsKelly, Adrian L.; Gough, Timothy D.; Dhumal, Ravindra S.; Halsey, S.A.; Paradkar, Anant R.
 
TitleApoptosis-induced anticancer effect of transferrin-conjugated solid lipid nanoparticles of curcumin (2012)
AuthorsMulik R.;Mönkkönen J.;Juvonen R.;Mahadik K.;Paradkar A.
JournalCancer Nanotechnology
DOI10.1007/s12645-012-0031-2
 
TitleProbing influence of mesophasic transformation on performance of self-emulsifying system: effect of ion (2012)
AuthorsPatil, S.S.; Venugopal, E.; Bhat, S.; Mahadik, K.R.; Paradkar, Anant R.
 
TitleMicrostructural elucidation of self-emulsifying system: effect of chemical structure (2012)
AuthorsPatil, S.S.; Venugopal, E.; Bhat, S.; Mahadik, K.R.; Paradkar, Anant R.
 
TitleQuality by design approach: Application of artificial intelligence techniques of tablets manufactured by direct compression (2012)
AuthorsAksu B.;Paradkar A.;De Matas M.;Özer O.;Güneri T.;York P.
JournalAAPS PharmSciTech
DOI10.1208/s12249-012-9836-x
 
TitleEvaluation of local drug-delivery system containing 2% whole turmeric gel used as an adjunct to scaling and root planing in chronic periodontitis: A clinical and microbiological study (2011)
AuthorsBehal R.;Mali A.;Gilda S.;Paradkar A.
JournalJournal of Indian Society of Periodontology
DOI10.4103/0972-124X.82264
 
TitleCharacterization of thermal and rheological properties of zidovidine, lamivudine and plasticizer blends with ethyl cellulose to assess their suitability for hot melt extrusion (2011)
AuthorsMaru S.;De Matas M.;Kelly A.;Paradkar A.
JournalEuropean Journal Of Pharmaceutical Sciences
DOI10.1016/j.ejps.2011.09.003
 
TitlePreparation and evaluation of talc agglomerates obtained by wet spherical agglomeration as a substrate for coating (2011)
AuthorsJadhav N.;Pawar A.;Paradkar A.
JournalPharmaceutical Development and Technology
DOI10.3109/10837450903544567
 
TitleDevelopment and validation of a densitometric HPTLC method for simultaneous analysis of wedelolactone and asiaticoside in a polyherbal formulation (2010)
AuthorsSathiyanarayanan L.;Paradkar A.;Mahadik K.
JournalActa Chromatographica
DOI10.1556/AChrom.22.2010.4.13
 
TitleTransferrin mediated solid lipid nanoparticles containing curcumin: Enhanced in vitro anticancer activity by induction of apoptosis (2010)
AuthorsMulik R.;Mönkkönen J.;Juvonen R.;Mahadik K.;Paradkar A.
JournalInternational Journal of Pharmaceutics
DOI10.1016/j.ijpharm.2010.07.021
 
TitleEffect of drug content and agglomerate size on tabletability and drug release characteristics of bromhexine hydrochloridetalc agglomerates prepared by crystallo-co-agglomeration (2010)
AuthorsJadhav N.;Pawar A.;Paradkar A.
JournalActa Pharmaceutica
DOI10.2478/v10007-010-0002-2
 
TitleCocrystalization and simultaneous agglomeration using hot melt extrusion (2010)
AuthorsDhumal, Ravindra S.; Kelly, Adrian L.; York, Peter; Coates, Philip D.; Paradkar, Anant R.
 
TitleStudy of polymorphs of progesterone by novel melt sonocrystallization technique: A technical note (2010)
AuthorsTripathi R.;Biradar S.;Mishra B.;Paradkar A.
JournalAAPS PharmSciTech
DOI10.1208/s12249-010-9508-7
 
TitleApoE3 mediated poly(butyl) cyanoacrylate nanoparticles containing curcumin: study of enhanced activity of curcumin against beta amyloid induced cytotoxicity using in vitro cell culture model (2010)
AuthorsMulik, R.S.; Monkkonen, J.; Juvonen, R.O.; Mahadik, K.R.; Paradkar, Anant R.
 
TitleUltrasound assisted cocrystallization from solution (USSC) containing a non-congruently soluble cocrystal component pair: Caffeine/maleic acid (2010)
AuthorsAher S.;Dhumal R.;Mahadik K.;Paradkar A.;York P.
JournalEuropean Journal Of Pharmaceutical Sciences
DOI10.1016/j.ejps.2010.08.012
 
TitleParticle engineering using sonocrystallization: Salbutamol sulphate for pulmonary delivery (2009)
AuthorsDhumal R.;Biradar S.;Paradkar A.;York P.
JournalInternational Journal of Pharmaceutics
DOI10.1016/j.ijpharm.2008.10.006
 
TitleNootropic activity of lipid-based extract of Bacopa monniera Linn. compared with traditional preparation and extracts (2009)
AuthorsLohidasan S.;Paradkar A.;Mahadik K.
JournalJournal of Pharmacy and Pharmacology
DOI10.1211/jpp/61.11.0014
 
TitleNovel pepper extract for enhanced P-glycoprotein inhibition (2009)
AuthorsAher S.;Biradar S.;Gopu C.;Paradkar A.
JournalJournal of Pharmacy and Pharmacology
DOI10.1211/jpp.61.09.0007
 
TitleCefuroxime axetil solid dispersion with polyglycolized glycerides for improved stability and bioavailability (2009)
AuthorsDhumal R.;Biradar S.;Aher S.;Paradkar A.
JournalJournal of Pharmacy and Pharmacology
DOI10.1211/jpp.61.06.0006
 
TitleShear and extensional rheology of hydroxypropyl cellulose melt using capillary rheometry (2009)
AuthorsParadkar, Anant R.; Kelly, Adrian L.; Coates, Philip D.; York, Peter
 
TitleFree radical scavenging and anti-inflammatory activity of Indian propolis (2009)
AuthorsAmbardekar R.;Gilda S.;Mahadik K.;Harsulkar A.;Paradkar A.
JournalPharmacologyonline
 
TitleDevelopment of curcuminoids loaded poly(butyl) cyanoacrylate nanoparticles: Physicochemical characterization and stability study (2009)
AuthorsMulik R.;Mahadik K.;Paradkar A.
JournalEuropean Journal Of Pharmaceutical Sciences
DOI10.1016/j.ejps.2009.03.009
 
TitleStudy on mechanism for amorphous drug stabilization using Gelucire 50/13 (2009)
AuthorsShimpi S.;Mahadik K.;Paradkar A.
JournalChemical and Pharmaceutical Bulletin
DOI10.1248/cpb.57.937
 
TitleRheological investigation of self-emulsification process: Effect of co-surfactant (2009)
AuthorsBiradar S.;Dhumal R.;Paradkar A.
JournalJournal of Pharmacy and Pharmaceutical Sciences
 
TitlePreparation of amorphous cefuroxime axetil nanoparticles by sonoprecipitation for enhancement of bioavailability (2008)
AuthorsDhumal R.;Biradar S.;Yamamura S.;Paradkar A.;York P.
JournalEuropean Journal of Pharmaceutics and Biopharmaceutics
DOI10.1016/j.ejpb.2008.04.001
 
TitleDesign and evaluation of celecoxib porous particles using melt sonocrystallization. (2006)
AuthorsParadkar, Anant R.; Maheshwari, M.; Kamble, R.; Grimsey, Ian M.; York, Peter
 
Book Chapters
TitleAerosols in pharmaceutical product development (2019)
AuthorsDeb P.K.;Abed S.N.;Maher H.;Al-Aboudi A.;Paradkar A.;Bandopadhyay S.;Tekade R.K.
JournalDrug Delivery Systems
DOI10.1016/B978-0-12-814487-9.00011-9
 
TitleImpact of the Polymorphic Form of Drugs/NCEs on Preformulation and Formulation Development (2019)
AuthorsMHD Bashir Alsirawan, Anant Paradkar
JournalInnovative Dosage Forms: Design and Development at Early Stage
PublisherWiley‐VCH
DOIhttps://doi.org/10.1002/9783527812172.ch1
 
TitleProtein/peptide drug delivery systems: Practical considerations in pharmaceutical product development (2018)
AuthorsDeb P.K.;Al-Attraqchi O.;Chandrasekaran B.;Paradkar A.;Tekade R.K.
JournalBasic Fundamentals of Drug Delivery
DOI10.1016/B978-0-12-817909-3.00016-9
 
TitlePharmaceutical and biomedical applications of polymers (2018)
AuthorsDeb P.K.;Kokaz S.F.;Abed S.N.;Paradkar A.;Tekade R.K.
JournalBasic Fundamentals of Drug Delivery
DOI10.1016/B978-0-12-817909-3.00006-6