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researcher

Talat Nasim

Senior Lecturer in Therapeutics

Faculty/Dept/School School of Pharmacy and Medical Sciences
(Faculty of Life Sciences)
Emailt.nasim@bradford.ac.uk
Telephone +441274 236076

Biography

Currently Dr. Nasim is a Senior Lecturer in Therapeutics at the School of Pharmacy and Medical Sciences, the University of Bradford, UK. He is an Executive Member, Research and Knowledge Transfer Committee, Faculty of Life Sciences, University of Bradford, Local Ambassador, the Biochemical Society, United Kingdom, Adviser, the Commonwealth Scholarship Commission, United Kingdom, Executive Member, Global Network of Bangladeshi Biotechnologists (GNOBB). He has been the member of Editorial Boards of a number of international journals including Journal of Bioscience, International Journal of Perception in Public Health and acted as a Guest Editor for the journal Pain Research and Management.  
His research interests focus in the broader areas of Translational Medicine (gene identification to drug discovery).  He has identified a few key genes that cause disorders such as Pulmonary Hypertension and blood cancer and identified novel diagnostics and therapeutics. Importantly, his discoveries are being taught at the university level and he is the inventor of a number of diagnostic and therapeutic patents.
His contributions to science include publications in scientific journals, articles to local and national Bangladeshi daily newspapers and intellectual supports to scientific community around the world. He has published 70 articles including research papers in journals like Nature Genetics, Nature Protocols, Nature Communications, Nucleic Acids Research, Human Molecular Genetics. His research has been extensively highlighted in news media across the globe as evidenced in his interviews with CBA News (USA), Labmate https://www.labmate-online.com/news/news-and-views/5/university-of-bradford/diagnostic-clues-found-for-pah/48687 (UK) and Daily Prothom-alo (Bangladesh). He writes regularly in newspapers including the daily Jugantor, Daily Prothom-alo and Lalmonirhat Barta and edited books inaugurated by the Prime Minister of the Peoples Republic of Bangladesh.  
He has been promoting science in Bangladesh. He is the founder and Chief Adviser of the organization called Centre for Health Agriculture and Socio-economic Advancements (CHASA), which was incepted in 2008 at Lalmonirhat, Bangladesh. Since its inception, CHASA has provided more than 150 scholarships to local students at various levels from primary to college and supported research projects at universities which resulted in a few scientific publications.  
Dr. Nasim received his Ph.D degree from the University of Manchester Institute of Science and Technology (UMIST), UK. In his student life, he received 18 scholarships from various countries including Bangladesh, Switzerland, USA and UK. In fact, he is the first ever Bangladeshi student who received the Swiss Govt. Scholarship.  
Dr. Nasim was a co-recipient of the Best Scientist Award 2008 of Lalmonirhat Municipality (Bangladesh) and received nomination for the ‘Best Non-resident Bangladeshi Scientist-2019’ of Global Network of Bangladeshi Biotechnologists (GNOBB).

Professional activities

  • 01-JAN-13: King’s College London - Visiting Senior Research Fellow
  • 01-JAN-08: Agriculture and Socio-economic Advancements (CHASA), Bangladesh - Founder and Chief Adviser (Honorary)
  • 01-JAN-08: King’s College London - Senior Research Fellow
  • 01-JAN-06: King’s College London - Research Associate
  • 01-JAN-06: University of Leicester - Research Associate
  • 01-JAN-00: University of Leicester - Research Associate
  • 01-JAN-94: University of Geneva - Post-graduate Research Fellow
  • Academic Adviser: Commonwealth Scholarship Commission
  • Executive Member: Global Network of Bangladeshi Biotechnologists (GNOBB)
  • Life Member: Global Network of Bangladeshi Biotechnologists (GNOBB)
  • The Biochemical Society, UK
  • Journal of Bioscience
  • , Member: American Thoracic Society
  • , Member: Biochemical Society (UK)
  • Research and Knowledge Transfer, Faculty of Life Sciences,
  • 01-JAN-00: University of Manchester - PhD
  • 01-JAN-08: - Best Scientist Award
  • 01-JAN-19: - Outstanding Non-Resident Bangladeshi Scientists (Nomination)
  • English
  • Bengali

Publications

Peer Reviewed Journal
TitleBMPRII deficiency impairs apoptosis via the BMPRII-ALK1-BclX-mediated pathway in pulmonary arterial hypertension (2019)
AuthorsChowdhury H.;Sharmin N.;Yuzbasioglu Baran M.;Long L.;Morrell N.;Trembath R.;Nasim M.
JournalHuman Molecular Genetics
DOI10.1093/hmg/ddz047
 
TitleBMPRII deficiency impairs apoptosis via the BMPRII-ALK1-BclX-mediated pathway in pulmonary arterial hypertension (PAH) (2019)
AuthorsChowdhury, H.M.; Sharmin, N.; Yuzbasioglu Baran, M.; Long, L.; Morrell, N.W.; Trembath, R.C.; Nasim, Md. Talat
 
TitleAminoglycoside-mediated promotion of translation readthrough occurs through a non-stochastic mechanism that competes with translation termination (2018)
AuthorsChowdhury H.;Siddiqui M.;Kanneganti S.;Sharmin N.;Chowdhury M.;Nasim M.
JournalHuman Molecular Genetics
DOI10.1093/hmg/ddx409
 
TitleAminoglycoside-mediated promotion of translation readthrough occurs through a non-stochastic mechanism that competes with translation termination (2017)
AuthorsChowdhury, H.M.; Siddiqui, M.A.; Kanneganti, S.; Sharmin, N.; Chowdhury, M.W.; Nasim, Md. Talat
 
TitleAKAP95 regulates splicing through scaffolding RNAs and RNA processing factors (2016)
AuthorsHu, J.; Khodadadi-Jamayran, A.; Mao, M.; Shah, K.; Yang, Z.; Nasim, Md. Talat; Wang, Z.; Jiang, H.
 
TitleProteomics of tissue factor silencing in cardiomyocytic cells reveals a new role for this coagulation factor in splicing machinery control (2015)
AuthorsLento, S.; Brioschi, M.; Barcella, S.; Nasim, Md. Talat; Ghilardi, S.; Barbieri, S.S.; Tremoli, E.; Banfi, C.
 
TitleData for proteomic analysis of murine cardiomyocytic HL1 cells treated with siRNA against tissue factor (2015)
AuthorsBrioschi, M.; Lento, S.; Barcella, S.; Nasim, Md. Talat; Tremoli, E.; Banfi, C.
 
TitleInhibition of Overactive Transforming Growth Factor–β Signaling by Prostacyclin Analogs in Pulmonary Arterial Hypertension (2013)
AuthorsOgo, T.; Chowdhury, H.M.; Yang, J.; Long, T.; Li, X.; Torres Cleuven, Y.N.; Morrell, N.W.; Schermuly, R.T.; Trembath, R.C.; Nasim, Md. Talat
 
TitlePulmonary arterial hypertension: molecular genetic basis and emerging treatments (2012)
AuthorsSiddiqui, M.A.; Ogo, T.; Nasim, Md. Talat
 
TitleBMPR-II deficiency elicits pro-proliferative and anti-apoptotic responses through the activation of TGFbeta-TAK1-MAPK pathways in PAH (2012)
AuthorsNasim, Md. Talat; Ogo, T.; Chowdhury, H.M.; Zhao, L.; Chen, C-n.; Rhodes, C.; Trembath, R.C.
 
TitleRecurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes (2012)
AuthorsGraubert, T.A.; Shen, D.; Ding, L.; Okeyo-Owuor, T.; Lunn, C.L.; Shao, J.; Krysiak, K.; Harris, C.C.; Koboldt, D.C.; Larson, D.E.; McLellan, M.D.; Dooling, D.J.; Abbott, R.M.; Fulton, R.S.; Schmidt, H.; Kalicki-Veizer, J.; O'Laughlin, M.; Grillot, M.; Baty, J.; Heath, S.; Frater, J.L.; Nasim, Md. Talat; Link, D.C.; Tomasson, M.H.; Westervelt, P.; DiPersio, J.F.; Mardis, E.R.; Ley, T.J.; Wilson, R.K.; Walter, M.J.
 
TitleMolecular genetic characterization of SMAD signaling molecules in pulmonary arterial hypertension (2011)
AuthorsNasim, Md. Talat; Ogo, T.; Ahmed, Mohammed I.; Randall, R.; Chowdhury, H.M.; Snape, K.M.; Bradshaw, T.Y.; Southgate, L.; Lee, G.J.; Jackson, I.; Lord, G.M.; Gibbs, J.S.; Wilkins, M.R.; Ohta-Ogo, K.; Nakamura, K.; Girerd, B.; Coulet, F.; Soubrier, F.; Humbert, M.; Morrell, N.W.; Trembath, R.C.; Machado, R.D.
 
TitleStoichiometric imbalance in the receptor complex contributes to dysfunctional BMPR-II mediated signalling in pulmonary arterial hypertension (2008)
AuthorsNasim, Md. Talat; Ghouri, A.; Patel, B.; James, V.; Rudarakanchana, N.; Morrell, N.W.; Trembath, R.C.
 
Other Publication
Other typeReviews
TitleTargeting SOCS Proteins to Control JAK-STAT Signalling in Disease (2019)
AuthorsDurham G.;Williams J.;Nasim M.;Palmer T.
JournalTrends in Pharmacological Sciences
DOI10.1016/j.tips.2019.03.001