Title | Glycosyl disulfides: importance, synthesis and application to chemical and biological systems (2021) |
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Authors | Ribeiro Morais, G.; Falconer, R.A. |
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Journal | Organic and Biomolecular Chemistry |
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DOI | 10.1039/D0OB02079F |
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Title | Progress towards a clinically-successful ATR inhibitor for cancer therapy (2021) |
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Authors | Barnieh, F.M.; Loadman, P.M.; Falconer, R.A. |
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Journal | Current Research in Pharmacology and Drug Discovery |
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DOI | 10.1016/j.crphar.2021.100017 |
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Title | An assay for quantitative analysis of polysialic acid expression in cancer cells (2021) |
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Authors | Guo, X.; Elkashef, S.M.; Patel, A.; Ribeiro Morais, G.; Shnyder S.D.; Loadman, P.M.; Patterson, L.H.; Falconer, R.A. |
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Journal | Carbohydrate Polymers |
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DOI | 10.1016/j.carbpol.2021.117741 |
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Title | An efficient assay for identification and quantitative evaluation of potential polysialyltransferase inhibitors. (2020) |
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Authors | Guo X; Malcolm J.R.; Ali M.M.; Ribeiro Morais G; Shnyder S.D.; Loadman P.M.; Patterson L.H.; Falconer R.A. |
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Journal | ANALYST (PRINT) |
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DOI | 10.1039/d0an00721h |
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Title | Novel Ran-RCC1 inhibitory peptide-loaded nanoparticles have anti-cancer efficacy in vitro and in vivo (2019) |
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Authors | Haggag, Y.A.; Matchett, K.B.; Falconer, R.A.; Isreb, M.; Jones, J.; Faheem, A.; McCarron, P.; El-Tanani, Mohamed |
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Journal | Cancers |
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DOI | 10.3390/cancers11020222 |
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Title | Recent advances in the analysis of polysialic acid from complex biological systems (2019) |
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Authors | Guo, X.; Elkashelf, S.M.; Loadman, P.M.; Patterson, L.H.; Falconer, R.A. |
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Journal | Carbohydrate Polymers |
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DOI | 10.1016/j.carbpol.2019.115145 |
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Title | Theranostic nanoparticles enhance the response of glioblastomas to radiation (2019) |
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Authors | Wu, W.; Klockow, J.L.; Mohanty, S.; Ku, K.S.; Aghighi, M.; Melemenidis, S.; Chen, Z.; Li, K.; Ribeiro Morais, Goreti; Zhao, N.; Schlegel, J.; Graves, E.E.; Rao, J.; Loadman, Paul M.; Falconer, R.A.; Mukherjee, S.; Chin, F.T.; Daldrup-Link, H.E. |
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Journal | Nanotheranostics |
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DOI | 10.7150/ntno.35342 |
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Title | Membrane-type matrix metalloproteinases: expression, roles in metastatic prostate cancer progression and opportunities for drug targeting (2017) |
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Authors | Falconer, R.A.; Loadman, P.M. |
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Journal | Journal of Cancer Metastasis and Treatment |
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DOI | 10.20517/2394-4722.2017.40 |
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Title | Rationalized Computer-Aided Design of Matrix-Metalloprotease-Selective Prodrugs (2017) |
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Authors | Jain, M.; Harburn, J.J.; Gill, J.H.; Loadman, P.M.; Falconer, R.A.; Mooney, C.A.; Cobb, S.L.; Berry, David J. |
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Journal | Journal of Medicinal Chemistry |
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DOI | 10.1021/acs.jmedchem.6b01472 |
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Title | A novel theranostic strategy for MMP-14 expressing glioblastomas impacts survival (2017) |
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Authors | Mohanty, S.; Chen, Z.; Li, K.; Ribeiro Morais, G.; Klockow, J.; Yerneni, K.; Pasani, L.; Chin, F.T.; Mitra, S.; Cheshier, S.; Chang, E.; Gambhir, S.S.; Rao, J.; Loadman, P.M.; Falconer, R.A.; Daldrup-Link, H.E. |
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Journal | Molecular Cancer Therapeutics |
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DOI | 10.1158/1535-7163.MCT-17-0022 |
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Title | Exploring and Exploiting Acceptor Preferences of the Human Polysialyltransferases as a Basis for an Inhibitor Screen (2017) |
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Authors | Ehrit, J.; Keys, T.G.; Sutherland, Mark H.; Wolf, S.; Meier, C.; Falconer, R.A.; Gerardy-Schahn, R. |
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Journal | ChemBioChem |
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DOI | 10.1002/cbic.201700157 |
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Title | Polysialic acid sustains cancer cell survival and migratory capacity in a hypoxic environment (2016) |
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Authors | Elkashef, Sara M.; Allison, Simon J.; Sadiq, Maria; Basheer, Haneen A.; Ribeiro Morais, Goreti; Loadman, Paul M.; Pors, Klaus; Falconer, Robert A. |
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Journal | Scientific Reports |
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DOI | 10.1038/srep33026 |
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Title | The use of thermographic imaging to evaluate therapeutic response in human tumour xenograft models (2016) |
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Authors | Hussain, Nosheen; Connah, David; Ugail, Hassan; Cooper, Patricia A.; Falconer, Robert A.; Patterson, Laurence H.; Shnyder, Steven D. |
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Journal | Scientific Reports |
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DOI | 10.1038/srep31136 |
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Title | The Effect of Polysialic Acid Expression on Glioma Cell Nano-mechanics (2016) |
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Authors | Grant, Colin A.; Twigg, Peter C.; Saeed, Rida F.; Lawson, G.; Falconer, Robert A.; Shnyder, Steven D. |
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Journal | BioNanoScience |
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DOI | 10.1007/s12668-016-0192-2 |
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Title | An optimised assay for quantitative, high-throughput analysis of polysialyltransferase activity (2016) |
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Authors | Elkashef, Sara M.; Sutherland, Mark H.; Patterson, Laurence H.; Loadman, Paul M.; Falconer, Robert A. |
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Journal | ANALYST (PRINT) |
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DOI | 10.1039/c6an01073c |
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Title | Novel strategies for the synthesis of unsymmetrical glycosyl disulfides (2016) |
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Authors | Ribeiro Morais, Goreti; Springett, Bradley R.; Pauze, Martin; Schröder, Lisa; Northrop, Matthew; Falconer, Robert A. |
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Journal | Organic and Biomolecular Chemistry |
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DOI | 10.1039/c6ob00230g |
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Title | Tumor-Targeted Prodrug ICT2588 Demonstrates Therapeutic Activity Against Solid Tumors and Reduced Potential For Cardiovascular Toxicity (2014) |
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Authors | Gill, Jason H.; Loadman, Paul M.; Shnyder, Steven D.; Cooper, Patricia A.; Atkinson, Jennifer M.; Ribeiro Morais, Goreti; Patterson, Laurence H.; Falconer, Robert A. |
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Journal | Molecular Cancer Therapeutics |
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DOI | 10.1021/mp400760b |
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Title | Development of Novel Tumor-Targeted Theranostic Nanoparticles Activated by Membrane-Type Matrix Metalloproteinases for Combined Cancer Magnetic Resonance Imaging and Therapy (2014) |
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Authors | Ansari, C.; Tikhomirov, G.A.; Hong, S.H.; Falconer, Robert A.; Loadman, Paul M.; Gill, Jason H.; Castaneda, R.; Hazard, F.K.; Tong, L.; Lenkov, O.D.; Felsher, D.W.; Rao, J.; Daldrup-Link, H.E. |
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Journal | Small |
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DOI | 10.1002/smll.201301456 |
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Title | Carbohydrate-based molecules for Molecular Imaging in Nuclear Medicine (2013) |
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Authors | Ribeiro Morais G.;Falconer R.;Santos I. |
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Journal | European Journal of Organic Chemistry |
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DOI | 10.1002/ejoc.201201457 |
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Title | NCAM polysialylation during adherence transitions: Live cell monitoring using an antibody-mimetic EGFP-endosialidase and the viability dye DRAQ7 (2013) |
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Authors | Smith P.;Furon E.;Wiltshire M.;Chappell S.;Patterson L.;Shnyder S.;Falconer R.;Errington R. |
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Journal | Cytometry Part A |
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DOI | 10.1002/cyto.a.22306 |
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Title | Pharmacological Inhibition of polysialyltransferase ST8SiaII Modulates Tumour Cell Migration (2013) |
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Authors | Al-Saraireh, Yousef M.J.; Sutherland, Mark H.; Springett, Bradley R.; Freiberger, F.; Ribeiro Morais, Goreti; Loadman, Paul M.; Errington, R.J.; Smith, P.J.; Fukuda, M.; Gerardy-Schahn, R.; Patterson, Laurence H.; Shnyder, Steven D.; Falconer, Robert A. |
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Journal | PLoS ONE |
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DOI | 10.1371/journal.pone.0073366 |
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Title | Micro-community cytometry: Sensing changes in cell health and glycoconjugate expression by imaging and flow cytometry (2013) |
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Authors | Smith P.;Falconer R.;Errington R. |
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Journal | Journal of Microscopy |
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DOI | 10.1111/jmi.12060 |
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Title | Synthesis and biological evaluation of colchicine C-ring analogues tethered with aliphatic linkers suitable for prodrug derivatisation (2012) |
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Authors | Fournier-Dit-Chabert J.;Vinader V.;Santos A.;Redondo-Horcajo M.;Dreneau A.;Basak R.;Cosentino L.;Marston G.;Abdel-Rahman H.;Loadman P.;Shnyder S.;Díaz J.;Barasoain I.;Falconer R.;Pors K. |
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Journal | Bioorganic and Medicinal Chemistry Letters |
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DOI | 10.1016/j.bmcl.2012.09.104 |
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Title | An optimized method for the synthesis of amino-functionalized phosphatidylcholine (2012) |
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Authors | Kong F.;Morais G.;Falconer R.;Sutton C. |
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Journal | Tetrahedron Letters |
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DOI | 10.1016/j.tetlet.2011.11.100 |
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Title | Polysialyltransferase: A new target in metastatic cancer (2012) |
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Authors | Falconer R.;Errington R.;Shnyder S.;Smith P.;Patterson L. |
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Journal | Current Cancer Drug Targets |
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DOI | 10.2174/156800912803251225 |
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Title | Identification of an acetyl disulfide derivative in the synthesis of thiosialosides (2010) |
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Authors | Morais G.;Oliveira I.;Humphrey A.;Falconer R. |
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Journal | Carbohydrate Research |
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DOI | 10.1016/j.carres.2009.10.017 |
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Title | Development of a novel tumor-targeted vascular disrupting agent activated by membrane-type matrix metalloproteinases (2010) |
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Authors | Atkinson J.;Falconer R.;Edwards D.;Pennington C.;Siller C.;Shnyder S.;Bibby M.;Patterson L.;Loadman P.;Gill J. |
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Journal | Cancer Research |
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DOI | 10.1158/0008-5472.CAN-10-1440 |
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