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Biography

Pete Twigg heads the Clinical Technology programme at Bradford, which he initially developed in collaboration with local hospitals.  He is deeply involved with the development of healthcare science and technology education programmes at a national level. His research interests lie in the application of mechanical analysis to biological systems, ranging from cells to human movement. The biomaterials aspects of this work often build on his experience of micro- and nano-characterisation, making use of atomic force microscopy, nanoindentation and other engineering techniques, combined with biological and scientific techniques.  This has led to him heading national and international research projects. Current projects include the development of soft tissue substitute materials, tissue fixation devices, tissue engineering and tissue characterisation. He also works with medical devices to develop "smart" solutions, such as instrumented walking aids for rehabilitation.

Research

Research Groups: Advanced Materials Engineering Research Groups: Advanced Materials Engineering Orthopaedics and prosthetics mechanics have been a research interest for some time, including joint replacement, fracture fixation, orthotics and lower limb prosthetics. Techniques vary from friction and wear simulation and testing, through pseudo-static and dynamic mechanical testing, to 3D kinetic analysis. The kinematic and kinetic work is largely done using an 8 camera Vicon motion capture system, which has also been applied to pre and post-operative clinical subjects and investigation of the role of vision in negotiating obstacles, among other studies. Physiological measurement, such as electromyography, has also been linked to some kinetic studies, such as the investigation of fatigue effects. Orthopaedics and prosthetics mechanics have been a research interest for some time, including joint replacement, fracture fixation, orthotics and lower limb prosthetics. Techniques vary from friction and wear simulation and testing, through pseudo-static and dynamic mechanical testing, to 3D kinetic analysis. The kinematic and kinetic work is largely done using an 8 camera Vicon motion capture system, which has also been applied to pre and post-operative clinical subjects and investigation of the role of vision in negotiating obstacles, among other studies. Physiological measurement, such as electromyography, has also been linked to some kinetic studies, such as the investigation of fatigue effects.

Professional activities

  • Surrey - BEng
  • Newcastle - PhD
  • 01-SEP-16: Cardiff University - External Examiner
  • 01-JAN-18: Leeds University - External Examiner
  • 01-SEP-18: Engineering and Informatics Faculty Board,
  • 01-SEP-16: HEFCE MedTech Catalyst Executive Board,
  • 01-SEP-11: University Council,
  • 01-SEP-09: University Senate,
  • 01-SEP-09: Biomedical, Natural and Physical Sciences Research Ethics Panel,
  • Employer Engagement
  • Medical and Healthcare Technology
  • Programme Leader: Clinical Technology BSc
  • EPSRC Associate Peer Review College member:
  • Person Designate, Human Tissue Authority:

Publications

Peer Reviewed Journal
TitleIn Situ Cross-Linking of Poly(vinyl alcohol)/Graphene Oxide-Polyethylene Glycol Nanocomposite Hydrogels as Artificial Cartilage Replacement: Intercalation Structure, Unconfined Compressive Behavior, and Biotribological Behaviors (2018)
AuthorsMeng Y.;Ye L.;Coates P.;Twigg P.
JournalJournal of Physical Chemistry C
DOI10.1021/acs.jpcc.7b12465
 
TitleIn Situ Cross-Linking of Poly(vinyl alcohol)/Graphene Oxide–Polyethylene Glycol Nanocomposite Hydrogels as Artificial Cartilage Replacement: Intercalation Structure, Unconfined Compressive Behavior, and Biotribological Behaviors (2018)
AuthorsMeng, Y.; Coates, Philip D.; Twigg, Peter C.
 
TitleMechanism of hydrogen-bonded complex formation between ibuprofen and nanocrystalline hydroxyapatite (2017)
AuthorsRyabenkova, Yulia; Jadav, Niten B.; Conte, M.; Hippler, M.F.A.; Reeves-McLaren, N.; Coates, Philip D.; Twigg, Peter C.; Paradkar, Anant R.
 
TitleThe Effect of Polysialic Acid Expression on Glioma Cell Nano-mechanics (2016)
AuthorsGrant, Colin A.; Twigg, Peter C.; Saeed, Rida F.; Lawson, G.; Falconer, Robert A.; Shnyder, Steven D.
JournalBioNanoScience
 
TitleTattoo ink nanoparticles in skin tissue and fibroblasts (2015)
AuthorsGrant, Colin A.; Twigg, Peter C.; Baker, Richard; Tobin, Desmond J.
 
TitleNano-scale temperature dependent visco-elastic properties of polyethylene terephthalate (PET) using atomic force microscope (AFM) (2013)
AuthorsGrant, Colin A.; Al-Fouzan, Abdulrahman M.; Gough, Timothy D.; Twigg, Peter C.; Coates, Philip D.
 
TitlePseudostatic and dynamic nanomechanics of the tunica adventitia in elastic arteries using atomic force microscopy (2013)
AuthorsGrant, Colin A.; Twigg, Peter C.
 
TitleEstimating the mechanical properties of retinal tissue using contact angle measurements of a spreading droplet (2013)
AuthorsGrant, Colin A.; Twigg, Peter C.; Savage, M.D.; Woon, W.H.; Wilson, M.C.T.; Greig, D.
 
TitleMechanical investigations on agar gels using atomic force microscopy: Effect of deuteration (2012)
AuthorsGrant C.;Twigg P.;Savage M.;Woon W.;Greig D.
JournalMacromolecular Materials and Engineering
DOI10.1002/mame.201100164
 
TitleStatic and dynamic nanomechanical properties of human skin tissue using atomic force microscopy: Effect of scarring in the upper dermis. (2012)
AuthorsGrant, Colin A.; Twigg, Peter C.; Tobin, Desmond J.
 
TitleMechanical Investigations on Agar Gels Using Atomic Force Microscopy: Effect of Deuteration. (2011)
AuthorsGrant, Colin A.; Twigg, Peter C.; Savage, M.D.; Woon, W.H.; Greig, D.
 
TitleHigh resolution imaging of bio-molecular binding studies using a widefield surface plasmon microscope (2008)
AuthorsJamil, M. Mahadi Abdul; Youseffi, Mansour; Twigg, Peter C.; Britland, Stephen T.; Liu, S.; See, C.W.; Zhang, J.; Somekh, M.G.; Denyer, Morgan C.T.
 
TitleAFM relative stiffness measurement of the plasticising effect of a non-ionic surfactant on plant leaf wax (2008)
AuthorsGrant, Colin A.; Twigg, Peter C.; Bell, G.; Lu, J.R.
 
TitleA comparative study of wire fixation and screw fixation in arthrodesis for the correction of hallux rigidus using an in vitro biomechanical model (2007)
AuthorsFaraj A.;Naraen A.;Twigg P.
JournalFoot and Ankle International
DOI10.3113/FAI.2007.0016
 
TitleThe mechanics of landing when stepping down in unilateral lower-limb amputees (2006)
AuthorsTwigg, Peter C.; Jones, S.F.; Scally, Andy J.; Buckley, John G.
 
TitleThe role of the surface amorphous layer of articular cartilage in joint lubrication (2006)
AuthorsGraindorge S.;Ferrandez W.;Ingham E.;Jin Z.;Twigg P.;Fisher J.
JournalProceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine
DOI10.1243/09544119JEIM122
 
TitlePoly(vinyl alcohol) hydrogel as a biocompatible viscoelastic mimetic for articular cartilage. (2006)
AuthorsBritland, Stephen T.; Eagland, D.; Smith, Annie G.; Twigg, Peter C.; Grant, Colin A.; Egan, A.; Moody, A.; Crowther, N.J.
 
TitleThe effects of blurred vision on the mechanics of landing during stepping down by the elderly (2005)
AuthorsBuckley, John G.; Heasley, Karen J.; Twigg, Peter C.; Elliott, David B.
 
TitleBiphasic surface amorphous layer lubrication of articular cartilage (2005)
AuthorsGraindorge S.;Ferrandez W.;Jin Z.;Ingham E.;Grant C.;Twigg P.;Fisher J.
JournalMedical Engineering and Physics
DOI10.1016/j.medengphy.2005.05.001
 
TitleFalls in older people: effects of age and blurring vision on the dynamics of stepping (2005)
AuthorsHeasley, Karen; Buckley, John G.; Scally, Andy J.; Twigg, Peter C.; Elliott, David B.
 
TitleThe gait initiation process in unilateral lower-limb amputees when stepping up and stepping down to a new level (2005)
AuthorsTwigg, Peter C.; Buckley, John G.; Jones, S.F.; Scally, Andy J.
 
TitleFunctional outcome following bone transport reconstruction of distal tibial defects (2005)
AuthorsTwigg, Peter C.; Buckley, John G.; Giannikas, K.A.; Wilkes, R.A.
 
TitleStepping up to a new level: effects of blurring vision in the elderly (2004)
AuthorsHeasley, Karen; Buckley, John G.; Scally, Andy J.; Twigg, Peter C.; Elliott, David B.
 
TitleWet Erosive Wear of Alumina Densified with Magnesium Silicate Additions (2001)
AuthorsGalusek D.;Brydson R.;Twigg P.;Riley F.;Atkinson A.;Zhang Y.
JournalJournal of the American Ceramic Society
 
Book Chapter
TitleHandbook of Tissue Engineering Scaffolds (2019)
AuthorsO. Agbabiaka, S. Yousaf, M. Zare, M. Mozafari, M. Youseffi, P. Twigg and F. Sefat
JournalHandbook of Tissue Engineering Scaffolds
PublisherElsevier
DOIhttps://doi.org/10.1016/B978-0-08-102563-5.00014-9
 
TitleNano-Scale Observations of Tattoo Pigments in Skin by Atomic Force Microscopy (2015)
AuthorsGrant, Colin A.; Twigg, Peter C.; Tobin, Desmond J.
 
Conference Contribution
TitleProceedings of the International Conference on Multi-Material Mico Manufacture (4M) (2015)
AuthorsK.J. Nair, B.R.Whiteside, C. Tuinea-Bobe, P.Twigg, K.Norris, A. R.Paradkar
 
Other Publication
Other typeArticle
TitleNano-scale observations of tattoo pigments in skin by atomic force microscopy (2015)
AuthorsGrant C.;Twigg P.;Tobin D.
JournalCurrent Problems in Dermatology - Basel
DOI10.1159/000369187
 
Title Author(s)
2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology (2005)Marlafeka S.;Liu S.;Mahadi Abdul Jamil M.;Twigg P.;Britland S.;Denyer M.;See C.;Somekh M.