Dr. Gisela Helfer
Information about Dr. Gisela Helfer at the University of Bradford.
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Biography
Dr Gisela Helfer studied Biology and Zoology at the Universityof Salzburg, Austria. During her Master’s studies at the University ofSalzburg, she investigated the neurobiology of learning and imprintingbehaviour of Japanese quail chicks. After graduating, she moved to the MaxPlanck Institute for Ornithology in Andechs, Germany, where she initially workedon the hippocampal formation of migratory birds with Prof Ebo Gwinner and lateron circadian rhythms in vertebrates. Here, Gisela found her love for science ingeneral and chronobiology (the study of biological rhythms) in particular. FromAndechs, she started her northwards journey, first to do a PhD at theUniversity of Birmingham (UK) to work on circadian rhythms in birds and then totrain as a postdoctoral fellow at the Rowett Institute of Nutrition and Healthat the University of Aberdeen (UK) with Prof Peter Morgan. At the Rowett Institute,she established novel concepts in molecular mechanisms and pathways regulatingseasonal physiology. By combining in vivo studies with molecular biologyincluding neuron-targeted viral gene delivery, she characterised and identifiedfor the first-time pathways in the hypothalamus that control energy homeostasisand appetite regulation. Her work discovered a new role forVitamin A in the brain. Downstream of Vitamin A signalling she identified anovel neuroendocrine role for the adipokine chemerin in cellular remodellingand neuronal plasticity within the hypothalamus. Six years of postdocing, three moves and two childrenlater, she joined the University of Bradford, where she is now an AssociateProfessor in Physiology and Metabolism. In 2015, Gisela enjoyed sabbatical researchat the Centre of Ornithology, University of Otago (NZ) and in 20018, she visitedthe Department of Physiology, University of Ontario, Canada to work with ProfDenise Belsham. As independent research group leader at theUniversity of Bradford, she continues to work on chemerin molecular physiologyin the hypothalamus and investigates circadian rhythms in energy balanceregulation which has recently generated significant international recognition.Research
Dr Helfer’s main interests and areas of expertise are in neuroendocrinology and chronobiology. Her research so far has centred on the control of circadian rhythms and seasonality in vertebrates and this has recently led to investigations in the central regulation of growth and energy balanceProfessional activities
Information about education, employment and areas of particular interest for Dr. Gisela Helfer is as follows:
Employment
- University of Bradford, UK - Lecturer in Biomedical Science in the year 2016 (specified as 01/03/2016)
- Rowett Institute of Nutrition and Health, University of Aberdeen, UK - Research Fellow in the year 2009 (specified as 01/07/2009)
- School of Science and the Environment, University of Worcester, UK - Teaching Fellow in the year 2009 (specified as 01/01/2009)
- University of Birmingham, UK - Research Fellow in the year 2007 (specified as 01/01/2007)
- Max Planck Institute for Ornithology, Seewiesen, Germany - Research Assistant in the year 2001 (specified as 01/01/2001)
Education
- University of Birmingham, UK - PhD
- University of Salzburg, Austria - MSc (Mag.rer.nat.)
- University of Salzburg, Austria - BSc
- University of Bradford - FHEA
Publications
There are 24 publications involving or that are attributed to Dr. Gisela Helfer. They are listed as:
- peer reviewed journal (23)
- reviews (1)
Peer Reviewed Journal
Title | Year | Publication name | Journal | Volume | Pages | Authors | Editors | ISSN | Publisher | DOI | Location |
---|---|---|---|---|---|---|---|---|---|---|---|
A neuroendocrine role for chemerin in hypothalamic remodelling and photoperiodic control of energy balance | 2016 | Helfer, Gisela; Ross, A.W.; Thomson, L.M.; Mayer, C.D.; Stoney, P.N.; McCaffery, P.J.; Morgan, P.J. | |||||||||
Hypothalamic Wnt signalling and its role in energy balance regulation | 2016 | Helfer, Gisela; Tups, A. | |||||||||
Photoperiod Regulates Lean Mass Accretion, but Not Adiposity, in Growing F344 Rats Fed a High Fat Diet | 2015 | Ross, A.W.; Russell, L.; Helfer, Gisela; Thomson, L.M.; Dalby, M.J.; Morgan, P.J. | |||||||||
Photoperiodic Effects on Seasonal Physiology, Reproductive Status and Hypothalamic Gene Expression in Young Male F344 Rats | 2015 | Tavolaro, F.M.; Thomson, L.M.; Ross, A.W.; Morgan, P.J.; Helfer, Gisela | |||||||||
Dual signal transduction pathways activated by TSH receptors in rat primary 1 tanycyte cultures | 2015 | Bolborea, M.; Helfer, Gisela; Ebling, F.J.P.; Barrett, P. | |||||||||
Thyroid hormone activation of retinoic acid synthesis in hypothalamic tanycytes | 2016 | Stoney, P.N.; Helfer, Gisela; Rodrigues, D.; Morgan, P.J.; McCaffery, P.J. | |||||||||
A seasonal switch in histone deacetylase gene expression in the hypothalamus and their capacity to modulate nuclear signaling pathways | 2016 | Stoney, P.N.; Rodrigues, D.; Helfer, Gisela; Khatib, T.; Ashton, A.; Hay, E.A.; Starr, R.; Kociszewska, D.; Morgan, P.J.; McCaffery, P.J. | |||||||||
Chemerin: A multifaceted adipokine involved in metabolic disorders | 2018 | Helfer, Gisela; Wu, Q-F. | |||||||||
Neuromedin U partly mimics thyroid-stimulating hormone and triggers Wnt/β-catenin signalling in the photoperiodic response of F344 rats. | 2013 | Journal of Neuroendocrinology | 25 | Helfer G;Ross AW;Morgan PJ; | 1365-2826 | 10.1111/jne.12116 | |||||
Photoperiod regulates vitamin A and Wnt/β-catenin signaling in F344 rats. | 2012 | Endocrinology | 153 | Helfer G;Ross AW;Russell L;Thomson LM;Shearer KD;Goodman TH;McCaffery PJ;Morgan PJ; | 1945-7170 | 10.1210/en.2011-1792 | |||||
Photoperiodic expression of two RALDH enzymes and the regulation of cell proliferation by retinoic acid in the rat hypothalamus. | 2012 | Journal of Neurochemistry | 122 | Shearer KD;Stoney PN;Nanescu SE;Helfer G;Barrett P;Ross AW;Morgan PJ;McCaffery P; | 1471-4159 | 10.1111/j.1471-4159.2012.07824.x | |||||
Melatonin receptor expression in the zebra finch brain and peripheral tissues. | 2012 | Chronobiology International | 29 | Jones C;Helfer G;Brandstätter R; | 1525-6073 | 10.3109/07420528.2011.642912 | |||||
Thyroid hormone signalling genes are regulated by photoperiod in the hypothalamus of F344 rats. | 2011 | PLoS ONE | 6 | Ross AW;Helfer G;Russell L;Darras VM;Morgan PJ; | 1932-6203 | 10.1371/journal.pone.0021351 | |||||
Molecular analysis of clock gene expression in the avian brain. | 2006 | Chronobiology International | 23 | Helfer G;Fidler AE;Vallone D;Foulkes NS;Brandstaetter R; | 0742-0528 | 10.1080/07420520500521871 | |||||
Photoperiodic and Diurnal Regulation of WNT Signaling in the Arcuate Nucleus of the Female Djungarian Hamster, Phodopus sungorus. | 2016 | Endocrinology | 157 | Boucsein A;Benzler J;Hempp C;Stöhr S;Helfer G;Tups A; | 1945-7170 | 10.1210/en.2015-1708 | |||||
A unifying hypothesis for control of body weight and reproduction in seasonally breeding mammals | 2019 | Helfer, Gisela; Barrett, P.; Morgan, P.J. | |||||||||
Pleiotropic effects of proopiomelanocortin and VGF nerve growth factor inducible neuropeptides for the long-term regulation of energy balance. | 2020 | Molecular and Cellular Endocrinology | Helfer G;Stevenson TJ; | 1872-8057 | 10.1016/j.mce.2020.110876 | ||||||
Pleiotropic effects of proopiomelanocortin and VGF nerve growth factor inducible neuropeptides for the long-term regulation of energy balance | 2020 | Molecular and Cellular Endocrinology | 514 | Helfer G.;Stevenson T.J. | 0303-7207 | 10.1016/j.mce.2020.110876 | |||||
The effect of photoperiod and high fat diet on the cognitive response in photoperiod-sensitive F344 rats. | 2021 | Physiology and Behavior | McLean SL;Yun H;Tedder A;Helfer G; | 1873-507X | 10.1016/j.physbeh.2021.113496 | ||||||
Hypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice. | 2021 | Nature Communications | 12 | Mu W;Li S;Xu J;Guo X;Wu H;Chen Z;Qiao L;Helfer G;Lu F;Liu C;Wu QF; | 2041-1723 | 10.1038/s41467-021-22640-z | |||||
The Chemerin-CMKLR1 Axis is Functionally important for Central Regulation of Energy Homeostasis | 2022 | Frontiers in Physiology | 30 May 2022 | Yun, H: Dumbell, R: Hanna, K: Bowen, J; McLean, SL; Kantamneni, S; Pors, K; Wu, QF; Helfer, G | https://doi.org/10.3389/fphys.2022.897105 | ||||||
Editorial: Women in integrative physiology: 2021. | 2022 | Frontiers in Physiology | 13 | Helfer G;Kadmiel M;Jethwa PH; | 1664-042X | 10.3389/fphys.2022.1036614 | |||||
Cherries with different geographical origins regulate neuroprotection in a photoperiod-dependent manner in F344 rats | 2024 | Antioxidants | 13 | Francesca Manocchio, Francisca Isabel Bravo, Gisela Helfer, Begona Muguerza | MDPI | 10.3390/antiox13010072 |
Reviews
Title | Year | Publication name | Journal | Volume | Pages | Authors | Editors | ISSN | Publisher | DOI | Location |
---|---|---|---|---|---|---|---|---|---|---|---|
Endocrine drivers of photoperiod response | 2020 | 11 | 49 - 54 | Helfer G.;Dumbell R. | 2451-9650 | 10.1016/j.coemr.2020.01.001 |