Dr Farshid Sefat
Associate Professor
| Faculty/Dept/School | Faculty of Eng & Digital Technologies |
|---|---|
| f.sefat1@bradford.ac.uk | |
| Telephone | +441274 233679 |
Biography
Dr Farshid Sefat is Associate Professor and Programme Leader in Biomedical and Electronic Engineering Department at the University of Bradford (UK) and previously was head of Biomedical Engineering Department at King Faisal University (Saudi Arabia) and also a Visiting Professor at Stevens Institute of Technology (New Jersey, USA). He completed his post doctorate research assistant at University of Sheffield (UK) in the area of cornea tissue engineering. He received his Ph.D. (2011) and BEng. (2005) degrees from University of Bradford (UK) both in Biomedical Engineering mainly focus on bone cell engineering. He also obtained his MSc. (2006) in Cell and Tissue Engineering from Keele University (UK).
His research is based on developing biomaterials to control cellular behaviour with particular emphasis in developing engineered materials for various tissue engineering applications. He is an author on >100 peer-reviewed journal articles, editorials and review papers and >30 book chapters/edited books. He is on the editorial boards and reviewer of >30 numerous journals including Materials Today, Acta Biomaterialia, IEEE, Bone, MDPI, Journal of Orthopaedics & Rheumatology, Materials Science and Engineering C, Journal of Biomechanics and many more.
Research
Key areas of research interest: 1. Skin, Hair, Breast and Cornea Tissue Engineering 2. Oral/Dental Tissue Engineering 3. Bone and Cartilage Cell Engineering 4. Dental Biomaterials 5. Biomaterials Fabrication & Characterization 6. Effect of Mechanical Stimulation on Bone Cell Behaviour 7. Effects of Growth Factors on Cell Behaviour (Cell Signalling) 8. Synthesis of Antibacterial Peptides for Dental Implant Modification Current research areas include: 1. Optimisation of layer-by-layer 3D scaffold for dermal wound healing 2. Fabrication and characterisation of biodegradable scaffolds for cornea tissue engineering 3. Cell signalling pathways of Transforming Growth Factor Beta (TGF-β isomers) 4. Investigating breast cancer behaviour using tissue engineering scaffolds 5. Electrospun nanofibers for vascular tissue engineeringTeaching
Teaching interests
Regenerative Medicine
Biomaterials
Scaffold for Tissue Engineering
Mathematics for Clinical Technologies
Cell culture Techniques
Cell and Tissue Biology
Design, Build, Test
Radiology and Radiation Engineering
Teaching highlights
Skills of Biomedical Engineering
Materials Technology and Structural Mechanics
Anatomy & Physiology
Infection Control
Professional activities
- 01-JAN-18: MeDe UK Best Video Award
- 01-JAN-13: Best Paper award for 4th International Conference on Biotech
- 01-JAN-11: Best Paper award for 13th Annual White Rose Meeting, Biomate
- 01-JAN-10: Best paper award of World Congress of Engineering (WCE 2010)
- 01-JAN-10: Best paper award of World Congress of Engineering (WCE 2010)
- 01-JAN-09: Best paper award of World Congress of Engineering (WCE 2009)
- 01-JAN-09: Best paper award of World Congress of Engineering (WCE 2009)
Publications
| Title | Comparison of biophysical properties characterized for microtissues cultured using microencapsulation and liquid crystal based 3D cell culture techniques (2018) |
|---|---|
| Authors | Soon C.;Tee K.;Wong S.;Nayan N.;Sargunan Sundra;Ahmad M.;Sefat F.;Sultana N.;Youseffi M. |
| Journal | Cytotechnology |
| DOI | 10.1007/s10616-017-0168-2 |
| Title | Synthesis of Indolo[3,2-b]carbazoles via an Anomeric-Based Oxidation Process: A Combined Experimental and Computational Strategy (2018) |
| Authors | Zolfigol, M.A.; Khazaei, A.; Karimitabar, F.; Hamidi, M.; Maleki, F.; Aghabarari, B.; Sefat, Farshid; Mozafari, M. |
| Title | Transplantation of adipose tissue-derived stem cells into brain through cerebrospinal fluid in rat models: Protocol development and initial outcome data. (2018) |
| Authors | Amini N;Vousooghi N;Alizade A;Ramezani S;Joghataei MT;Milan PB;Mehrabi S;Ababzadeh S;Sefat F;Mozafari M; |
| Journal | Current Stem Cell Research and Therapy |
| DOI | 10.2174/1574888X13666180720112322 |
| Title | Shape-controlled silver NPs for shape-dependent biological activities (2017) |
| Authors | Sadeghi, F.; Yazdanpanah, A.; Abrishamkar, A.; Moztarzadeh, F.; Ramedani, A.; Pouraghaie, S.; Shirinzadeh, H.; Samadikuchaksaraei, A.; Chauhan, N.P.S.; Hopkinson, L.; Sefat, Farshid; Mozafari, M. |
| Title | Fabrication and Characterisations of Hydrogels for Cartilage Repair (2017) |
| Authors | 11. Kaur, P., Khaghani, S.A., Oluwadamilola, A., Khurshid, Z., Zafar, M.S., Mozafari, M., Youseffi, M and Sefat, F |
| Journal | Journal of tissue engineering and regenerative medicine |
| Title | Biosynthetic PCL-graft-collagen bulk material for tissue engineering applications (2017) |
| Authors | Gentile, P.; McColgan-Bannon, K.; Gianone, N.C.; Sefat, Farshid; Dalgarno, K.; Ferreira, A.M. |
| Title | The Effect of WIN55, 212-2 on Protein S100, Matrix Metalloproteinase-2 and Nitric Oxide Expression of Chondrocyte Monolayer (2017) |
| Authors | Abdeldayem A, Youseffi M, Sefat F, Genedy M, Abdul Jamil, M.M., Javid F. |
| Journal | Journal of Biomedical Engineering |
| Title | Improved cell infiltration of electrospun nanofiber mats for layered tissue constructs (2016) |
| Authors | Mahjour, S.B.; Sefat, Farshid; Polunin, Y.; Wang, L.; Wang, H. |
| Title | Effect of transforming growth factor-β on up/down regulation of integrin-β1 in primary chondrocyte culture (2016) |
| Authors | Khaghani, Seyed A.; Sefat, Farshid; Youseffi, Mansour; Rehman, R.; Soon, Chin Fhong; Akbarova, G. |
| Title | Dental Applications of Nanodiamonds (2016) |
| Authors | Najeeb, S.; Khurshid, Z.; Agwan, A.S.; Zafar, M.S.; Alrahabi, M.; Bin Qasim, S.; Sefat, Farshid |
| Title | Effect of Transforming Growth Factor-β3 on mono and multilayer chondrocytes (2016) |
| Authors | Sefat, Farshid; Youseffi, Mansour; Khaghani, Seyed A.; Soon, Chin Fhong; Javid, Farideh A. |
| Title | Histatin peptides: Pharmacological functions and their applications in dentistry (2016) |
| Authors | Khurshid, Z.; Najeeb, S.; Mali, M.; Moin, S.F.; Raza, S.Q.; Zohaib, S.; Sefat, Farshid; Zafar, M.S. |
| Title | Potential of electrospun nanofibers for biomedical and dental applications (2016) |
| Authors | Zafar, M.S.; Najeeb, S.; Khurshid, Z.; Vazirzadeh, M.; Zohaib, S.; Najeeb, B.; Sefat, Farshid |
| Title | Rocking Media Over Ex Vivo Corneas Improves This Model and Allows the Study of the Effect of Proinflammatory Cytokines on Wound Healing (2015) |
| Authors | Deshpande, P.; Ortega, Í.; Sefat, Farshid; Sangwan, V.S.; Green, N.H.; Claeyssens, F.; MacNeil, S. |
| Title | Transforming growth factor beta (TGF-β) isomers influence cell detachment of MG-63 bone cells (2015) |
| Authors | Sefat, Farshid; Khaghani, Seyed A.; Nejatian, T.; Genedy, Mohamed A.; Abdeldayem, Ali I.A.; Moghaddam, Z.S.; Denyer, Morgan C.T.; Youseffi, Mansour |
| Title | Impact of packing and processing technique on mechanical properties of acrylic denture base materials (2015) |
| Authors | Nejatian, T.; Sefat, Farshid; Johnson, T. |
| Title | Rapid creation of skin substitutes from human skin cells and biomimetic nanofibers for acute full-thickness wound repair (2015) |
| Authors | Mahjour, S.B.; Fu, X.; Yang, X.; Fong, J.; Sefat, Farshid; Wang, H. |
| Title | Transforming Growth Factor Beta (TGF-β): Natural Curing Agents for Repair (2014) |
| Authors | Sefat, Farshid |
| Title | Development of a Basement Membrane Substitute Incorporated Into an Electrospun Scaffold for 3D Skin Tissue Engineering (2014) |
| Authors | Bye, F.J.; Bullock, A.J.; Singh, R.; Sefat, Farshid; Roman, S.; MacNeil, S. |
| Title | Effects of different transforming growth factor beta (TGF-β) isomers on wound closure of bone cell monolayers (2014) |
| Authors | Sefat, Farshid; Denyer, Morgan C.T.; Youseffi, Mansour |
| Title | Combination of Microstereolithography and Electrospinning to Produce Membranes Equipped with Niches for Corneal Regeneration (2014) |
| Authors | Ortega, Í.; Sefat, Farshid; Deshpande, P.; Paterson, T.; Ramachandran, C.; Ryan, A.J.; MacNeil, S.; Claeyssens, F. |
| Title | Increasing elastin fibre production in a tissue engineered mesh for pelvic floor surgery (2014) |
| Authors | Osman, N.; Roman, S.; Sefat, Farshid; Bullock, A.J.; Chapple, C.R. |
| Title | Production, Sterilisation and Storage of Biodegradable Electrospun PLGA Membranes for Delivery of Limbal Stem Cells to the Cornea (2013) |
| Authors | Sefat, F., McKean, R., Deshpande, P., Ramachandran, C., Hill, C., Sangwan, V., Ryan, A. and MacNeil, S. |
| Journal | Procedia Engineering |
| Title | Simplifying corneal surface regeneration using a biodegradable synthetic membrane and limbal tissue explants. (2013) |
| Authors | Deshpande P;Ramachandran C;Sefat F;Mariappan I;Johnson C;McKean R;Hannah M;Sangwan VS;Claeyssens F;Ryan AJ;MacNeil S; |
| Journal | Biomaterials |
| DOI | 10.1016/j.biomaterials.2013.03.064 |
| Title | Imaging via widefield surface plasmon resonance microscope for studying bone cell interactions with micropatterned ECM proteins (2011) |
| Authors | Sefat F.;Denyer M.;Youseffi M. |
| Journal | Journal of Microscopy |
| DOI | 10.1111/j.1365-2818.2010.03430.x |