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Dr. Arathyram Ramachandra Kurup Sasikala,
Assitant Professor in Formulation Science

Information about Dr. Arathyram Ramachandra Kurup Sasikala at the University of Bradford.

Norcroft Building
(University of Bradford)
Email:
a.ramachandrakurupsasikala@bradford.ac.uk
Telephone:
+44 1274 238049
Photo of Dr. Arathyram Ramachandra Kurup Sasikala

Biography

Dr. Arathyram Ramachandra Kurup Sasikala is an Assistant Professor at the Centre for Pharmaceutical Engineering Science and Institute of Cancer Therapeutics at the Faculty of Life Sciences.Her vision is to develop next-generation nanotherapeutics for human diseases with unmet clinical needs through non-invasive approaches.She is an interdisciplinary biomaterial scientist who completed her master’s degree in Physics and continued her journey toward nanomedicine research and worked on the interface between materials science and biology.After receiving her doctorate from the Department of Bionanosystem Engineering, Jeonbuk National University (JBNU) South Korea, she was quickly recognised for her work with a three-year Young Investigator Award from the National Research Foundation of Korea. Meanwhile, she's taken a position as an Assistant Research Professor at the JBNU. Her role as an independent PI allowed her to serve as Primary Supervisor for two master's theses and as Co-supervisor for one doctoral thesis.To further develop her career as an independent research leader in next-generation biomaterials, she moved to the University of Birmingham as a Marie Curie Fellow, where she investigated a new strategy for the non-invasive modulation of the Blood-Brain Barrier to overcome the unmet need for delivering drugs to the brain.Arathyram is passionate about communicating her research to the public and patients through PPI meetings and various outreach activities like European Researchers Night, Nottingham Soapbox Science, Pint of Science etc. She is the Outreach, Collaborations, and Dissemination Lead of the Centre for Pharmaceutical Engineering Science.

Research

I have a strong interest in thedevelopment and translation of next-generation nanotherapeutics to addressbreakthrough healthcare challenges. I have always tried to broaden my horizonsthrough interdisciplinary research and partnerships since receiving my Ph.D. andthroughout my academic career. Our group is focused on developing innovativeways for producing smart and hybrid organic-inorganic nanomaterials withdesirable properties to be used as targeted drug delivery carriers, non-invasiveanticancer agents, tissue regeneration matrices, and bioimaging platforms. Inour research, we use a highly interdisciplinary approach and work at theintersection of materials science, engineering, and biology.Some ongoing research areasinclude:

1. Synthesis of multifunctional nanomaterialsfor cancer theranostics Application

  • Magnetichyperthermia
  • MagneticResonance Imaging
  • Photothermaltherapy
  • Photodynamictherapy
  • SecondHarmonic Generation Imaging
2. Development of non-invasive BloodBrain Barrier modulators for targeted drug delivery to the brain

  • Nanoelectroporation
  • PiezoMagneticnanoparticles
  • Carbonnanoneedles

3. Remotely controlled stimuli-responsiveDrug Delivery systems

  • PH sensitive
  • Ultrasound sensitive
  • Magnetic field sensitive
  • Light Sensitive

4. Development of ImplantableAnticancer Devices (IADs)

  • Electrospun nanofiber-based IADs
  • Hydrogels based IADs
  • Microneedle based IADs

5. Biomimetic nanomaterials forregenerative medicine Application

  • Piezoelectricwhitlockite nanoparticles

  • PiezoelectricNerve conduits

  • PiezoelectricBone implants

  • PiezoelectricWound dressing patches

Professional activities

Information about education, employment and areas of particular interest for Dr. Arathyram Ramachandra Kurup Sasikala is as follows:

Employment

  • Jeonbuk National University, South Korea - Assistant Research Professor in the year 2016 (specified as 01/12/2016)
  • National Remote Sensing Centre, Indian Space Research Organisation, India - Junior Research Fellow in the year 2011 (specified as 14/07/2011)
  • University of Birmingham - Marie Curie Individual Fellow in the year 2020 (specified as 21/09/2020)