Skip to content

PHD Studentship: Adaptation and community dynamics of the human oral microbiome over centuries of evolution

No longer applicable

This scholarship is no longer available due to the passing deadline, or it was for a previous academic year.

The scholarship may be available in future academic years, but this may not always be the case. Please make sure you check the relevant academic year for more information.

Note: This page remains online for information purposes only.

The human microbiome is composed of two categories of microbes: commensals (beneficial to the host) and pathogens (detrimental to host health). While we know quite a lot about modern microbiomes in terms of what bacteria live there, how they enter the body and how the specific body site select for certain bacteria, little is known about the historical evolution of the human microbiome. How have commensals and pathogens interacted over the past thousand years in and on our bodies? What bacteria rely on what other bacteria for survival and has this changed over time?

Understanding three core aspects of the human microbiome (evolution, adaptation and interconnectedness) would better allow us to examine the effect of diet and human health on our resident microbes and in turn understand how shaping the microbial community in our bodies could better benefit our health.

This project aims to address these questions, focussing on the human oral cavity microbiome. Using dental calculus microbiome whole genome data collected over 5000 years from Yorkshire archaeological skeletons, we will reconstruct the evolution of the human oral microbiome in Northern England and examine the influence of diet, antibiotic exposure and urbanisation on this community. Next, by combining this dataset with modern global samples, we can extensively explore the human oral microbiome community ecology, including genetic exchange and metabolic handovers. This will allow us to investigate whether modern microbiomes interact and respond to change better than historical counterparts.

Study level:
Postgraduate Research
Academic entry year:
2021/22
Attendance of study:
full-time
Available to:
prospective students
Scholarships available:
This scholarship or bursary is only available to one successful applicant.

Eligiblity

This type of historical and wide-ranging investigation of the community dynamics of the oral microbiome has never been performed and will extensively advance our understanding of this crucial aspect of human health with high relevance to the local Bradford community. We are looking for an enthusiastic PhD candidate, preferably with a background in some (but not necessarily all) of the following topics: bioinformatics, molecular evolution, microbial ecology, phylogenetics

  • Afghanistan
  • Aland Islands
  • Albania
  • Algeria
  • American Samoa
  • Andorra
  • Angola
  • Anguilla
  • Antigua & Barbuda
  • Antilles (Netherlands)
  • Argentina
  • Armenia
  • Aruba
  • Australia
  • Austria
  • Azerbaijani Republic, The
  • Bahamas, The
  • Bahrain
  • Bangladesh
  • Barbados
  • Belarus
  • Belgium
  • Belize
  • Benin
  • Bermuda
  • Bhutan
  • Bolivia
  • Bonaire, Sint Eustatius and Saba
  • Bosnia And Herzegovina
  • Botswana
  • Bouvet Island
  • Brazil
  • British Antarctic Territories
  • British Indian Ocean Territory
  • British Virgin Islands
  • Brunei Darussalam
  • Burkina Faso; Also Upper Volta
  • Bulgaria
  • Burundi
  • Myanmar
  • Cameroon
  • Canada
  • Cape Verde Islands
  • Cayman Islands
  • Canary Islands
  • Central African Republic
  • Chad
  • Channel Islands, not elsewhere specified
  • Chile
  • China
  • Christmas Island
  • Cocos (Keeling) Islands
  • Colombia
  • Comoros
  • Congo (Peoples Republic)
  • Congo, Democratic Republic
  • Cook Islands
  • Costa Rica
  • Croatia
  • Cuba
  • Cura
  • Cyprus (European Union)
  • Cyprus (Non-European Union)
  • Czech Republic
  • Denmark
  • Djibouti
  • Dominica
  • Dominican Republic
  • Timor Leste (East Timor)
  • Ecuador
  • Egypt, United Arab Republic of
  • El Salvador
  • England
  • Equatorial Guinea
  • Eritrea
  • Estonia
  • Ethiopia
  • Falkland Islands (Malvinas)
  • Faroe Islands
  • Fiji
  • Finland
  • France
  • French Guiana
  • French Polynesia
  • Gabon
  • Gambia, The Republic of The
  • Georgia
  • Germany
  • Ghana
  • Gibraltar
  • Greece
  • Greenland
  • Grenada
  • Guadeloupe
  • Guam
  • Guatemala
  • Guernsey
  • Guinea
  • Guinea Bissau
  • Guyana
  • Haiti
  • Honduras
  • Hong Kong
  • Hungary
  • Iceland
  • India
  • Indonesia
  • Iran
  • Iraq
  • Ireland, the Republic of
  • Isle of Man (The)
  • Israel
  • Italy
  • Cote D'Ivoire (Ivory Coast)
  • Jamaica
  • Japan
  • Jersey
  • Jordan
  • Cambodia
  • Kazakhstan
  • Kenya
  • Kiribati (The Gilbert Islands)
  • Korea (North), Democratic Peoples Republic of
  • Korea (South), Republic of
  • Kosovo
  • Kuwait
  • Kyrgyzstan
  • Laos People's Democratic Republic
  • Latvia
  • Lebanon
  • Lesotho
  • Liberia
  • Libya
  • Liechtenstein
  • Lithuania
  • Luxembourg
  • Macao (Special Administrative Region of China)
  • Macedonia
  • Madagascar
  • Malawi
  • Malaysia
  • Maldive Islands
  • Mali
  • Malta
  • Martinique
  • Mauritania
  • Mauritius
  • Mayotte (French Territorial Collectivity)
  • Mexico
  • Moldova, Republic of
  • Monaco
  • Mongolia
  • Montenegro
  • Montserrat
  • Morocco
  • Mozambique
  • Namibia
  • Nauru
  • Nepal
  • Netherlands
  • New Caledonia, also French Overseas Territori
  • New Zealand
  • Nicaragua
  • Niger
  • Nigeria
  • Niue
  • Norfolk Island
  • Northern Ireland
  • Northern Mariana Islands
  • Norway
  • Oman
  • Pakistan
  • Palau
  • Palestine; West Bank; Gaza Strip inc E Jerusa
  • Panama
  • Papua New Guinea
  • Paraguay
  • Peru
  • Philippines
  • Pitcairn, Henderson, Ducie and Oenno Islands
  • Poland
  • Portugal
  • Puerto Rico
  • Qatar
  • Reunion
  • Romania
  • Russia
  • Rwanda
  • Samoa, Independent State of
  • San Marino
  • Sao Tome & Principe
  • Saudi Arabia
  • Scotland
  • Senegal
  • Serbia
  • Seychelles
  • Sierra Leone
  • Singapore
  • Sint Maarten (Dutch part)
  • Slovakia
  • Slovenia
  • Solomon Islands
  • Somalia
  • South Africa
  • South Sudan
  • Spain
  • Sri Lanka
  • St Helena, Ascension and Tristan da Cunha
  • St Pierre and Miquelon
  • St.Kitts and Nevis
  • St.Lucia
  • St.Vincent and the Grenadines
  • Sudan
  • Suriname
  • Svalbard and Jan Mayen
  • Swaziland
  • Sweden
  • Switzerland
  • Syrian Arab Republic
  • Taiwan
  • Tajikistan
  • Tanzania, United Republic of
  • Thailand
  • Togo
  • Tokelau
  • Tonga
  • Trinidad & Tobago
  • Tunisia
  • Türkiye
  • Turkmenistan
  • Turks & Caicos Islands
  • Tuvalu
  • Uganda
  • Ukraine
  • United Arab Emirates
  • United States of America
  • United States Virgin Islands
  • Uruguay
  • Uzbekistan
  • Vanuatu
  • Vatican City, Holy See Vatican City State
  • Venezuela
  • Vietnam
  • Wales
  • Wallis and Futuna
  • Western Sahara
  • Windward Islands (not otherwise specified)
  • Yemen, Republic of
  • Zambia
  • Zimbabwe

Payment amount & frequency

This project has full funding for UK students, which will cover tuition and bench fees, and a stipend for living costs. Non-UK students, including those from EU countries, may be considered but would need to self-fund the difference between UK and International fees

How to apply

Applicants should apply via the following link

Application deadline: 26 March 2021

Further information about this scholarship

For informal enquiries, please contact: research@bradford.ac.uk