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Particle Size Reduction

Particle size reduction provides a number of attractions to the pharmaceutical formulator for the enhanced delivery of drugs with low aqueous solubility, primarily it markedly increases in surface area to volume ratio.

Lena V1000
  • Small Scale Micronisation- CPES offers lab scale micronisation minimum requirement 2g.
  • High Pressure Homogenistion-Preparation of liquid/solid dosage forms.
  • Nanoprocessing- Wet Bead Milling; Preparation of liquid /solid dosage forms of nanoparticulate suspensions/solids.
 

Through our partners Lena Nanoceutics Ltd CPES can offer access to proven, cost effective, rapid and consistent particle size reduction technology that has been shown to produce nanoparticles (in the range 200-400nm) in aqueous suspension.

 

Microniser Controlled stability studies have proven that the suspensions are stable over a period of 6 months. These nanoparticles have successfully been incorporated into solid dosage forms to provide enhanced in-vivo dissolution and absorption for drugs with low aqueous solubility.