Molecular Mechanisms of Toxicity

Module code: INC7009-B

Module Aims 

To develop a critical evaluative understanding of the molecular mechanism underlying cellular toxicity.

Emphasis is placed on emerging concepts that reflect the changing nature of modern drug development. The module will address the mechanisms responsible for drug target toxicity and the evolution of new preclinical strategies to identify and predict such mechanisms.

The module is structured as a combination of lectures, tutorials, student-led seminars and laboratory investigation, plus student directed learning.

The student led seminars consist of the preparation and delivery of a drug profile presentation, where students indvidually review and present a selected drug profile with an emphasis on toxicity and in vitro screening methods as an alternative to in vivo toxicology. The laboratory investigation includes the preparation of a detailed experimental report covering methods, data collection and data analysis and interpretation.

The acquired knowledge will be assessed by coursework evaluation and examination at the end of the semester.

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