Module code: PHA4009-C
To introduce students to new concepts of drug discovery, design and synthesis, through the fundamental molecular structure and the chemistry of essential reactions to the drug molecules passage through the body. This is illustrated using the concepts of Absorption, Distribution, Metabolism and Excretion (ADME). To explore the drug development cycle and manufacturing regulations to ensure the safe and effective production, storage, packaging and environmentally appropriate disposal of medicines and drug delivery systems.
To introduce and familiarise students with the processes and procedures of drug development from plant to patient by exploring the principles of:
Origins of drugs, drug discovery process and drug synthesis.
Molecular structure and functional groups and their interplay.
Principles of drug design and structure-activity relationships.
Different drug delivery systems.
Drug packaging and safe storage.
Theories of drug administration and absorption including physicochemical properties of drug molecules.
Processes of drug distribution, metabolism and excretion including essential reactions.
Medicines disposal and their effect on the environment.
Clinical trials process and the regulatory framework around the testing of medicines to assure their quality, safety and efficacy including an introduction to the aseptic preparation of medicines.