Module code: BIS4007-B
To provide an introduction to the major classes of biomolecules involved in storing or deriving energy and to consider the processes of metabolism. To promote an understanding of how these molecules function in an integrated manner in the living body and to learn some of the fundamental biochemical principles of reaction kinetics, equilibrium and imaging techniques. To learn how biochemistry is applied in the modern world – from clinic to research.
Introduction, aims and relevance; Block 1: Molecules of Life: Covalent, and non-covalent bonding in biomolecules, basic structure and function of nucleotides and nucleic acids; carbohydrates, fatty acids and amino acids, Buffers and equilibria; Block 2: Energy generation and metabolism: Enzyme structure, factors affecting catalysis, enzyme kinetics, co-factors, inhibition and regulation, Energy generation via TCA cycle and Electron transport chain, Glycogen metabolism, Amino acid metabolism and Urea cycle, Lipid metabolism. Block 3: Studying biomolecules: biochemistry applied in the modern world from clinic to research, basic principles of imaging techniques used in biochemistry, introduction into biochemistry in disease.
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