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New computer-aided model may help predict sepsis


Can a computer-aided model predict life-threatening sepsis? A UK-developed model that uses routinely collected data to identify early symptoms of sepsis, published in CMAJ (Canadian Medical Association Journal), shows promise.

Sepsis is a major cause of death in hospitals and early detection is key to preventing deaths. Every hour of delay is linked to a 7% reduction in survival but delays in detection are common. Several scores exist to help identify patients with sepsis, including the National Early Warning Score (NEWS) now used in about two-thirds of the United Kingdom's National Health Service hospitals.

Researchers in the UK developed a computer-aided National Early Warning Score (cNEWS) to determine if it could enhance the accuracy of predicting sepsis.

"The main advantage of these computer models is that they are designed to incorporate data that exists in the patient record, can be easily automated and place no extra burden on the clinician to collect additional information," says Dr. Mohammed Mohammed, University of Bradford.

The cNEWS score can trigger screening for sepsis usually within 30 minutes of admission once routinely collected information has been electronically entered into the patient's medical record.

"These risk scores should support, rather than replace, clinical judgement. We hope they will heighten awareness of sepsis with additional information on this serious condition," says Dr. Mohammed.

cNEWS may now be carefully introduced into hospitals with appropriate infrastructure and evaluated.

Computer aided National Early Warning Score to predict the risk of sepsis following emergency medical admission to hospital: a model development and external validation study was published April 8, 2019.