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Dr Karthik Nair

Dr Karthik Nair

BIOGRAPHY +

Dr Nair graduated from Bharathi Vidyapeeth College of Pharmacy (India) with a Bachelor Degree in Pharmacy and he gained a PGDip in pharmacology from Nottingham Trent University. He also has an MSc in drug delivery from Aston University, Birmingham. In 2014 he completed his PhD in Pharmaceutical Engineering from Polymer IRC, University of Bradford and since then he is working as a Post-Doctoral Researcher on Healthcare Impact Partnership project on Smart Manufacturing of Medical Devices for soft tissue fixation (e.g. rotator cuff and anterior cruciate ligament repairs; fixations for fracture (including intramedullary nails) and knee joint replacements). The aim of this collaborative project is to exploit unique capabilities in shape memory polymers and biomaterials for enhanced biomedical cementless fixations using controlled shape reversion, in clinically relevant timescales, and open up opportunities for new solutions in orthopaedic repairs, which will have a defined route to regulatory certification and a clear patent pathway.

Main research projects include:

Healthcare: bioresorbable shape memory materials for bone and soft tissue fixation, novel extrusion manufacturing of drugs, drug delivery devices, metered dose inhalers, microneedles, drug-eluting implants and medical devices.

Basic science: Molecular architecture effects on processing, ultra-high strain rate rheometry, AFM of polymers, biomedical materials and nanocomposites.

Novel & efficient processing: Micro-injection moulding, ultrasound moulding solid phase orientation processing, die drawing, extrusion, quality control and additives compounding.


Research and Areas of Expertise:

Drug-eluting devices
Extrusion
Microneedles
Injection moulding
Ultrasound moulding
Soft tissue fixation of medical devices
Die drawing/solid phase orientation
Nanostructures with antibacterial properties
Particle engineering,Spray drying


Existing collaborations
UK: University of Loughborough, Nottingham University, Cardiff
University and University of Leeds (MeDe).
India: Indian Institute of Science Bangalore, Institute of Chemical
Technology Mumbai and Mahatma Gandhi university Kerala.
China: Institute of Applied Chemistry CAS, Changchun and Shanghai
Institute of Material Medica, Shanghai.
Industry: SABIC (Netherlands), Renephra Ltd (Manchester), Innovate
orthopaedics and Smith & Nephew.


AWARDS AND RECOGNITION +

An associate fellow of the higher education academy.

Aston University Life & Health Sciences Scholarship Award 2009.

Reckitt Benckiser Open Minds Winner 2011.
RB open minds is a competition for PhD students to come up with a
formulation and business ideas to increase the sales of already
established products in the market.

BBSRC Biotechnology YES (Young Entrepreneurs Scheme) participant
2012 (Represented University of Bradford)
The Biotechnology Young Entrepreneurs Scheme (Biotechnology YES) is
an innovative competition for postgraduate researchers and
postdoctoral scientists which raise awareness of the
commercialisation of ideas from the biosciences. The competition is
organised jointly by UNIEI " The Haydn Green Institute Innovation
Skills Group and BBSRC.

RECENT PUBLICATIONS +

Uppuluri C, Shaik AS, Han T, Nayak A, Nair KJ, Whiteside BR, Nalluri BN & Das D; Effect of Microneedle Type on Transdermal Permeation of Rizatriptan, AAPS PharmSciTech, (2017);18(5):1495-1506.

Nalluri BN, Uppuluri C, Devineni J, Nayak A, Nair KJ, Whiteside BR & Das D, Effect of microneedles on transdermal permeation enhancement of amlodipine, Drug Deliv Transl Res, (2017) 3;7(3):383-394.

Uppuluri C, Devineni J, Tao H, Nayak A, Nair KJ, Whiteside BR, Das & Nalluri BN, Microneedle-assisted transdermal delivery of Zolmitriptan: effect of microneedle geometry, in vitro permeation experiments, scaling analyses and
numerical simulations. Drug Dev Ind Pharm, (2017) (8):1292-1303.

Nair K, Grant C, Whiteside B, Bobe C, Patel R, Norris K & Paradkar A, Investigation of plasma treatment on polymeric micro-injection moulded microneedle for protein drug delivery, Pharmaceutics 2015, 7(4), 471-485.

Jadhav N and Nair K, Glass transition temperature: Basics and application in the pharmaceutical sector. Asian Journal of Pharmaceutics, 2009, 2(3).85-89.

Profile last updated on: 06-11-2018