Dr Adrian Kelly
- Title: Reader in Polymer Engineering
- Email: A.L.Kelly@Bradford.ac.uk
- Extension: 4532
- Room No. Richmond WG29B
- Additional Role: Industrial Placements Tutor
- Additional Role: Chemical Engineering Stage III Tutor
- Additional Role: Extrusion Manager, IRC in Polymer Engineering
- Research Groups: Advanced Materials Engineering
- Research Groups: Centre for Pharmaceutical Engineering Science
BIOGRAPHY +
Adrian Kelly BEng (Hons) PhD CEng MIMechE PgCHEP FHEA
Dr Kelly graduated in Mechanical Engineering and was awarded a PhD in 1997 for industrially sponsored research into process rheometry of extrusion compounding. He then took up a post doctoral post in the IRC Polymer Engineering research group at the University of Bradford working on a range of polymer processing based research projects. In 2003 Dr Kelly managed a WRAP funded project to investigate recycling of PVC-rich waste and in 2005 he was awarded funding from the DTI for a research project aimed at encouraging the UK polymer industry to adopt process metrology.
Dr Kelly became a Research Investment Lecturer in 2005 and was promoted to Senior Lecturer in Polymer Engineering in 2011. He teaches in materials, thermodynamics, polymer engineering and computer monitoring and instrumentation at undergraduate and MSc level. He is the Placements Tutor for the School of Engineering. His current research interests include process monitoring, thermal optimisation, pharmaceutical polymer engineering, nanocomposites, biopolymers, recyclates and fuel cells. In 2010 he co-founded the Centre for Pharmaceutical Engineering Science with colleagues in Engineering and Life Sciences; he is also active in the Centre of Advanced Materials Engineering and the the Centre for Polymer Micro and Nano Technology.
GRANTS +
Current, and significant recent, funded projects
Innovate UK (KTP with AstraZeneca) Hot Melt Extrusion (£90k) 2015-2017
EPSRC Graphene-Polypropylene Composite Nets for Filtration (£100k) 2016-2017
UKIERI (British Council) Structuring of polymeric matrices for controlled drug release (£27.5k) 2014-2015
Innovate UK (KTP with Corrosion Resistant Products Ltd) Corrosion Resistant Fluoropolymers (£125k) 2013-2015
EPSRC Novel Continuous Method for Co-crystal Formation (£550k) 2011-2014
EPSRC Thermal Management of Polymer Processing (£225k) 2010-2013
TSB High Volume Production of Membrane Electrode Assembly Fuel Cells (£235k) 2009-2012
EU FP7 PolySense Ultrasonic Monitoring of Polymer Processing (£220k) 2011-2012
RESEARCH STAFF +
Dr Eleni Moschopoulou - Graphene based nanocomposites for filtration media
RESEARCH STUDENTS +
Completed PhD Students
Gulstan Ezat - Dispersion and orientation of carbon nanotubes in polypropylene (May 2012)
Chaitrali Kulkarni - Melt extruded formulations of Artermisinin (Feb 2014)
Prafulla Apshingekar - Ultrasonic characterisation of pharmaceutical polymer formulations (Nov 2014)
Rohan Ambardekar - Solid phase orientation of pharmaceutical polymer systems (May 2015)
Javier Vera Sorroche - Thermal optimisation of single screw extrusion (May 2015)
Sachin Korde - Pharmaceutical solid dispersions (July 2015)
Shivprasad Deshmukh - Injection moulding of pharmaceuticals (Aug 2015)
Basak Tuna - Reactive extrusion of polyamide nanocomposite (Oct 2016)
Clive Wood - Continuous cocrystallisation (Dec 2016)
Current Research Students
Abdolati Alwati - Ultrasonic cocrystallisation
Cayetano Martinez Alcaraz - Ultrasonic characterisation of filled polymers
Aniket Sabnis - Hot melt extrusion of pharmaceuticals
Banah Shriky - Hydrogels for drug delivery applications
Millan-John Gilson - Injection moulding of long fibre composites
Nikolaos Kassos - Development of biobased polymers
Vasiliki Papadopolou - Polymer gel electrolytes for lithium ion batteries
Azad Mohammed - Pharmaceutical granulation
Asim Sajid - Pharmaceutical crystal engineering
Mohammad Salhab - Drug delivery systems to target postoperative pain in orthopaedic surgery
PUBLICATIONS
Journal Publications +
-
Meng L., Wu D., Kelly A., Woodhead M. and Liu Y. (2017): "Geometry dependence of the elongation behavior of a polypropylene melt through a micro die" Polymer Testing, 59 185-192.
For more information see: http://www.sciencedirect.com/science/article/pii/S0142941816313484 -
Meng L., Wu D., Kelly A., Woodhead M. and Liu M. (2017): "Comparisons of the rheological behaviours of polypropylene and polymethyl methacrylate in a capillary die" Journal of Applied Polymer Science, 134 (12).
For more information see: http://onlinelibrary.wiley.com/doi/10.1002/app.44617/abstract -
Laske S., Paudel A., Scheibelhofer O., Sacher S. and Kelly A. (2017): "A review of PAT strategies in secondary solid oral dosage manufacturing of small molecules" Journal of pharmaceutical sciences, 106 (3): 667-712.
For more information see: http://www.sciencedirect.com/science/article/pii/S0022354916418496 -
Apshingekar P.P., Aher S., Kelly A.L., Brown E.C. and Paradkar A. (2017): "Synthesis of Caffeine/Maleic Acid Co-crystal by Ultrasound-assisted Slurry Co-crystallization" Journal of pharmaceutical sciences, 106 (1): 66-70.
For more information see: http://www.sciencedirect.com/science/article/pii/S002235491641703X -
Abeykoon C., Kelly A.L., Brown E.C. and Coates P.D. (2016): "Process Settings and Screw Geometry on Energy Consumption and Melt Temperature in Single Screw Extrusion" Applied Energy, 180 172-181.
For more information see: http://www.sciencedirect.com/science/article/pii/S0306261916309552 -
Wood C., Alwati A.A., Halsey S.A., Gough T. and Kelly A.L. (2016): "Near infra red spectroscopy as a multivariate process analytical tool for predicting pharmaceutical co-crystal concentration" Journal of Pharmaceutical and Biomedical Analysis, 129 172-181.
For more information see: http://www.sciencedirect.com/science/article/pii/S0731708516303272 -
Meng L., Wu D., Kelly A., Woodhead M. and Liu Y. (2016): "Experimental investigation of the rheological behaviours of polypropylene in a capillary flow" Journal of Applied Polymer Science, 133 (22).
For more information see: http://onlinelibrary.wiley.com/doi/10.1002/app.43459/full -
Kulkarni C., Wood C., Kelly A.L., Gough T. and Paradkar T. (2015): "Stoichiometric Control of Co-Crystal Formation by Solvent Free Continuous Co-Crystallization (SFCC)" Crystal Growth and Design, 15 (12): 5648-5651.
For more information see: http://pubs.acs.org/doi/abs/10.1021/acs.cgd.5b00806 -
Kelly A.L., Halsey S.A., Bottom R.A., Korde S. and Gough S. (2015): "A Novel Transflectance Near Infrared Spectroscopy Technique for Monitoring Hot Melt Extrusion" International Journal of Pharmaceutics, 496 (1): 117-123.
For more information see: http://www.sciencedirect.com/science/article/pii/S0378517315300442 -
Vera Sorroche J., Kelly A.L., Brown E.C. and Coates P.D. (2015): "Infrared Melt Temperature Measurement of Single Screw
Extrusion" Polymer Engineering and Science, 55 (5): 1059-1066.
For more information see: http://onlinelibrary.wiley.com/doi/10.1002/pen.23976/abstract -
Karandikar H., Ambardekar R., Kelly A., Gough T. and Paradkar T. (2015): "Systematic identification of thermal degradation products of HPMCP
during hot melt extrusion process" International Journal of Pharmaceutics, 486 252-258.
For more information see: http://www.sciencedirect.com/science/article/pii/S0378517315003142 -
Abeykoon C., Vera Sorroche J., Kelly A.L., Brown E.C. and Coates P.D. (2014): "Process Efficiency in Polymer Extrusion: Correlation between the Energy Demand and Melt Thermal Stability" Applied Energy, 135 560-571.
For more information see: http://www.sciencedirect.com/science/article/pii/S030626191400909X -
Vera Sorroche J., Kelly A.L., Brown E.C., Gough T. and Abeykoon C. (2014): "The Effect of Melt Viscosity on Thermal Efficiency for Single Screw Extrusion of HDPE" Chemical Engineering Research and Design, 92 (11): 2404-2412.
For more information see: http://www.sciencedirect.com/science/article/pii/S0263876213005431 -
Abeykoon C., Kelly A.L., Brown E.C., Vera-Sorroche J. and Coates P.D. (2014): "Investigation of the Temperature Homogeneity of Die Melt Flows in Polymer Extrusion" Polymer Engineering and Science, 54 (10): 2430-2440.
For more information see: http://onlinelibrary.wiley.com/doi/10.1002/pen.23784/abstract -
Lin X., Kelly A., Woodhead M., Ren D. and Wang K. (2014): "Capillary Study on Geometrical Dependence of Shear Viscosity of Polymer Melts" Journal of Applied Polymer Science, 131 (6).
For more information see: http://onlinelibrary.wiley.com/doi/10.1002/app.39982/abstract -
Abeykoon C., Li K., Martin P.J. and Kelly A.L. (2014): "Dynamic modelling of die melt temperature profile in polymer extrusion: Effects of process settings, screw geometry and material" Applied Mathematical Modelling, 38 1224-1236.
For more information see: http://www.sciencedirect.com/science/article/pii/S0307904X1300509X -
Mahmah O., Tabbakh R., Kelly A. and Paradkar A. (2014): "A comparative study of the effect of spray drying and hot melt extrusion on the properties of amorphous solid dispersions containing felodipine" Journal of Pharmacy and Pharmacology, 66 (2): 275-284 .
For more information see: http://onlinelibrary.wiley.com/doi/10.1111/jphp.12099/abstract -
Deng J., Li K., Harkin-Jones E., Price M. and Kelly A. (2014): "Low-cost process monitoring for polymer extrusion" Transactions of the Institute of Measurement and Control, 36 (3): 382-390.
For more information see: http://tim.sagepub.com/content/early/2013/09/26/0142331213502696.abstract?rss=1 -
Deng J., Li K., Harkin-Jones E., Price M. and Kelly A.L. (2014): "Energy monitoring and quality control of a single screw extruder" Applied Energy, 113 1775-1785.
For more information see: http://www.sciencedirect.com/science/article/pii/S0306261913007289 -
Abeykoon C., Kelly A.L., Brown E.C., Vera Sorroche J. and Coates P.D. (2014): "Investigation of the Process Energy Demand in Polymer Extrusion: A Brief Review and an Experimental Study" Applied Energy, 136 726-737.
For more information see: http://www.sciencedirect.com/science/article/pii/S0306261914009714 -
Bao W., Wu H., Guo S., Paradkar A. and Kelly A. (2014): "Effect of Ultrasound on Molecular Structure Development of Poly-Lactide Acid" Polymer - Plastics Technology and Engineering, 53 (9): 927-934.
For more information see: http://www.tandfonline.com/doi/abs/10.1080/03602559.2014.886062 -
Lin X., Kelly A., Woodhead M., Ren D. and Wang D. (2013): "Geometrical dependence of Viscosity of Polymethylmethacrylate Melt in Capillary Flow" Journal of Applied Polymer Science, 130 (5): 3384-3394.
For more information see: http://onlinelibrary.wiley.com/doi/10.1002/app.39591/abstract -
Kulkarni C., Kelly A., Kendrick J., Gough T. and Paradkar A. (2013): "Mechanism of polymorphic transformation of artemisinin during high temperature extrusion" Crystal Growth and Design, 13 (12): 5157-5161 .
For more information see: http://pubs.acs.org/doi/abs/10.1021/cg400891b -
Vera-Sorroche J., Kelly A., Brown E., Coates P. and Karnachi P. (2013): "Thermal Optimisation of Polymer Extrusion using In-process Monitoring Techniques" Applied Thermal Engineering, 53 (2): 405-413.
For more information see: http://www.sciencedirect.com/science/article/pii/S1359431112002566 -
Kulkarni C., Kendrick J., Kelly A., Gough T. and Paradkar A. (2013): "Polymorphic transformation of artemisinin by high temperature extrusion" CrystEngComm, 15 (32): 6297-6300.
For more information see: http://pubs.rsc.org/en/Content/ArticleLanding/2013/CE/c3ce40726h#!divAbstract -
Ezat G.S., Kelly A.L., Mitchell S.C., Youseffi M. and Coates P.D. (2012): "Effect of maleic anhydride grafted polypropylene compatibiliser on the morphology and properties of polypropylene/multiwalled carbon nanotube composite" Polymer Composites, 33 (8): 1376-1386.
For more information see: http://onlinelibrary.wiley.com/doi/10.1002/pc.22264/abstract -
Abeykoon C., Martin P.J., Kelly A.L. and Brown E.C. (2012): "A review and evaluation of melt temperature sensors for polymer extrusion" Sensors and Actuators A-Physical, 182 16-27.
For more information see: http://www.sciencedirect.com/science/article/pii/S0924424712002658 -
Kelly A.L., Gough T., Dhumal R.S., Halsey S.A. and Paradkar A. (2012): "Monitoring ibuprofen-nicotinamide cocrystal formation during solvent free continuous cocrystallisation (SFCC) using near infrared spectroscopy as a PAT tool" International Journal of Pharmaceutics, 426 (1-2): 15-20.
For more information see: http://www.sciencedirect.com/science/article/pii/S0378517311011598 -
Abeykoon C., McAfee M., Li K., Martin P.J. and Kelly A.L. (2011): "The inferential monitoring of screw load torque to predict process fluctuations in polymer extrusion" Journal of Materials Processing Technology, 211 (12): 1907-1918.
For more information see: http://www.sciencedirect.com/science/article/pii/S092401361100135X -
Rides M., Kelly A.L. and Allen C.R. (2011): "An investigation of high rate capillary extrusion rheometry of thermoplastics" Polymer Testing, 30 (8): 916-924.
For more information see: http://www.sciencedirect.com/science/article/pii/S0142941811001437 -
Maru S.M., de Matas M., Kelly A. and Paradkar A. (2011): "Characterization of thermal and rheological properties of zidovidine, lamivudine and plasticizer blends with ethyl cellulose to assess their suitability for hot melt extrusion" European Journal of Pharmaceutical Sciences, 44 (4): 471-478.
For more information see: http://www.ncbi.nlm.nih.gov/pubmed/21925600 -
Ezat G., Kelly A., Mitchel S., Youseffi M. and Coates P.D. (2011): "Influence of maleic anhydride compatibiliser on properties of polypropylene/multiwalled carbon nanotube composites" Plastics Rubber and Composites, 40 (9): 438-448.
For more information see: http://www.maneyonline.com/doi/abs/10.1179/1743289810Y.0000000043 -
Kelly A.L., Mulvaney-Johnson L., Beechey R. and Coates P.D. (2011): "The Effect of Copper Alloy Mold Tooling on the Performance of the Injection Molding Process" Polymer Engineering and Science, 51 (9): 1837-1847.
For more information see: http://onlinelibrary.wiley.com/doi/10.1002/pen.21975/abstract -
Abeykoon C., Li K., McAfee M., Martin P.J. and Kelly A.L. (2011): "A new model based approach for the prediction and optimisation of thermal homogeneity in single screw extrusion" Control Engineering Practice, 19 (8): 862-874.
For more information see: http://www.sciencedirect.com/science/article/pii/S0967066111000815 -
Dhumal R.S., Kelly A.L., York P., Coates P.D. and Paradkar A. (2010): "Cocrystalization and Simultaneous Agglomeration using Hot Melt Extrusion" Pharmaceutical Research, 27 (12): 2725-2733.
For more information see: http://link.springer.com/article/10.1007%2Fs11095-010-0273-9#page-1 -
Kelly A.L., Gough T., Whiteside B.R. and Coates P.D. (2009): "High Strain Rate Rheometry of Polymer Melts" Journal of Applied Polymer Science, 114 864-873.
For more information see: http://onlinelibrary.wiley.com/doi/10.1002/app.30552/pdf -
Villanueva M.P., Cabedo L., Giminez E., Laragon J.M. and Kelly J.M. (2009): "Study of the Dispersion of Nanoclays in a LDPE Matrix Using Microscopy and In-Process Ultrasonic Monitoring" Polymer Testing, 28 277-287.
For more information see: http://www.sciencedirect.com/science/article/pii/S0142941808002146 -
Paradkar A., Kelly A., Coates P. and York P. P.(2009): "Shear and Extensional Rheology of Hydroxypropyl Cellulose Melt Using Capillary Rheometry" Journal of Pharmaceutical and Biomedical Analysis, 49 (2): 304-310.
For more information see: http://www.sciencedirect.com/science/article/pii/S0731708508006249