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Professor Stephen Rimmer

PositionHead of School of Chemistry and Forensic Sciences, and Professor of Chemistry
LocationM15, Richmond building
Department or DivisionChemistry and Forensic Sciences
Telephone+44 (0) 1274 233787
EmailS.Rimmer@bradford.ac.uk

Research Interests (key words only)

Polymers, Biomaterials, Radical Polymerisation, Cationic Polymerisation, Polyurethanes, Emulsion Polymerisation, Smart Polymers, Anti-microbial agents, Tissue Engineering, Drug delivery

Study History

1988: BSc (Hons) Polymer Science and Technology-Chemistry, University of Manchester

1992: PhD/DIC, Imperial College London

1992-1995: Post-Doctoral work, University of Lancaster

1995-2000: Lecturer-Senior Lecturer, University of Lancaster

2000-2012: Reader, University of Sheffield

2012-2015: Professor, University of Sheffield

2015 - present: Professor of Chemistry and Head of School of Chemistry and Forensic Sciences, University of Bradford

Also spent seven years in industrial research.

Professional Activities

Fellow of Royal Society of Chemistry (RSC).

Research Areas

Our work is focused on the synthesis and properties of functional polymers. We enjoy good collaborative relationships with large sections of the polymers and biomedical devices industry. Functional polymers are produced using a variety of methods including radical, cationic and ring-opening polymerisations as well as step-growth techniques such as polyurethane synthesis. We also make extensive use of polymerisations in disperse media; such as emulsion polymerisations.

Recently, one of our focuses has been on producing functional hydrogels to support cells for applications in tissue engineering. Here our aim is to control cells as they develop and grow and to examine how the structure of the materials affects performance and cell compatibility. Another strong theme is to use functional polymers to detect pathogens in infective diseases and here we are developing unique medical devices for use at the point of care. Many of the polymers are complex materials and analysis is difficult. To achieve full characterization we use a great deal of expertise in chromatographic techniques, advanced mass spectrometry and nuclear magnetic resonance spectroscopies; often coupling these techniques together.

Publications

"Nerve Guides Manufactured from Photocurable Polymers to aid Peripheral Nerve Repair" C. Pateman, A, Harding, A. Glen, C. Taylor, S. Rimmer, F. Boissonade, F. Claeyssens and J W Haycock Biomaterials 49 77 (2015)

"Amine functional hydrogels as selective substrates for corneal epithelialization" E. Hassan, P. Deshpande, F. Claeyssens, S. Rimmer, S. MacNeil Acta Biomater. 10 3029 (2014)

"Glucomannan-poly(N-vinyl pyrrolidinone) bicomponent hydrogels for wound healing" M. Shahbuddin, A.J. Bullock, S. MacNeil, S. Rimmer J. Mater. Chem.-B 2 727 (2014)

"Controlled delivery of cytokine growth factors mediated by core-shell particles with poly(acrylamidomethylpropane sulphonate) shells" L. Platt, L. Kelly, S. Rimmer J.Mater. Chem.-B 2 494 (2014)

"Arginine functionalisation of hydrogels for heparin binding – a supramolecular approach to developing a pro-angiogenic biomaterial" L. Gilmore, S. Rimmer, S.L. McArthur, S. Mittar, D. Sun, S. MacNeil, Biotech. Bioeng. 110 296 (2013)

"Thermally-reversible colloidal gels for 3D chondrocyte culture" J.W Lapworth, R. L. Goodchild, P.V Hatton, S. Rimmer, Roy. Soc. Interface, 9 362 (2012)

"Highly-branched polymers with polymyxin end groups responsive to Pseudomonas aeruginosa" P. Sarker, J. Shepherd, K. Swindells, I. Douglas, S. MacNeil, L. Swanson, S. Rimmer, Biomacromolecules, 12 1 (2011)

"Hyperbranched poly(NIPAM) polymers modified with antibiotics can both bind bacteria and reduce Gram-negative and Gram-positive bacterial burden in infected human tissue engineered skin" J. Shepherd, P. Sarker, S. Rimmer, L. Swanson, S. MacNeil, I. Douglas, Biomaterials, 32 258 (2011)

"Synthesis of Chain End Functionalized Linear and Branched Polymers by Non-Living Radical Polymerization in the Presence of a Silyl Enol Ether" R.M. England, S. Rimmer Chem. Commun., 46 5767 (2010)

"Binding bacteria to highly branched poly(N-isopropyl acrylamide) modified with vancomycin induces the coil-to-globule transition" J. Shepherd, P. Sarker, K. Swindells, I. Douglas, S. MacNeil, L. Swanson, S. Rimmer, J. Am. Chem. Soc., 132 1736 (2010)

 

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